Pesquisa | Secretaria de Estado da Saúde

1.

The big brain aquaporin is required for endosome maturation and notch receptor trafficking.

Kanwar, Ritu; Fortini, Mark E.

Cell ; 133(5): 852-63, 2008 May 30.

Artigo Inglês | MEDLINE | ID: mdl-18510929

2.

Protein trafficking abnormalities in Drosophila tissues with impaired activity of the ZIP7 zinc transporter Catsup.

Groth, Casper; Sasamura, Takeshi; Khanna, Mansi R; Whitley, Michael; Fortini, Mark E.

Development ; 140(14): 3018-27, 2013 Jul.

Artigo Inglês | MEDLINE | ID: mdl-23785054

3.

Disruption of Drosophila melanogaster lipid metabolism genes causes tissue overgrowth associated with altered developmental signaling.

Sasamura, Takeshi; Matsuno, Kenji; Fortini, Mark E.

PLoS Genet ; 9(11): e1003917, 2013 Nov.

Artigo Inglês | MEDLINE | ID: mdl-24244188

4.

Deficient Notch signaling associated with neurogenic pecanex is compensated for by the unfolded protein response in Drosophila.

Yamakawa, Tomoko; Yamada, Kenta; Sasamura, Takeshi; Nakazawa, Naotaka; Kanai, Maiko; Suzuki, Emiko; Fortini, Mark E; Matsuno, Kenji.

Development ; 139(3): 558-67, 2012 Feb.

Artigo Inglês | MEDLINE | ID: mdl-22190636

5.

Therapeutic approaches to modulating Notch signaling: current challenges and future prospects.

Groth, Casper; Fortini, Mark E.

Semin Cell Dev Biol ; 23(4): 465-72, 2012 Jun.

Artigo Inglês | MEDLINE | ID: mdl-22309842

6.

Pharmacological and genetic reversal of age-dependent cognitive deficits attributable to decreased presenilin function.

McBride, Sean M J; Choi, Catherine H; Schoenfeld, Brian P; Bell, Aaron J; Liebelt, David A; Ferreiro, David; Choi, Richard J; Hinchey, Paul; Kollaros, Maria; Terlizzi, Allison M; Ferrick, Neal J; Koenigsberg, Eric; Rudominer, Rebecca L; Sumida, Ai; Chiorean, Stephanie; Siwicki, Kathleen K; Nguyen, Hanh T; Fortini, Mark E; McDonald, Thomas V; Jongens, Thomas A.

J Neurosci ; 30(28): 9510-22, 2010 Jul 14.

Artigo Inglês | MEDLINE | ID: mdl-20631179

7.

gamma-cleavage-independent functions of presenilin, nicastrin, and Aph-1 regulate cell-junction organization and prevent tau toxicity in vivo.

Doglio, Laura E; Kanwar, Ritu; Jackson, George R; Perez, Mar; Avila, Jesús; Dingwall, Colin; Dotti, Carlos G; Fortini, Mark E; Feiguin, Fabián.

Neuron ; 50(3): 359-75, 2006 May 04.

Artigo Inglês | MEDLINE | ID: mdl-16675392

8.

Pharmacological analysis of Drosophila melanogaster gamma-secretase with respect to differential proteolysis of Notch and APP.

Groth, Casper; Alvord, W Gregory; Quiñones, Octavio A; Fortini, Mark E.

Mol Pharmacol ; 77(4): 567-74, 2010 Apr.

Artigo Inglês | MEDLINE | ID: mdl-20064975

9.

Inheritance of susceptibility to induction of nephroblastomas in the Noble rat.

Diwan, Bhalchandra A; Timofeeva, Olga; Rice, Jerry M; Yang, Yili; Sharma, Nirmala; Fortini, Mark E; Wang, Honghe; Perantoni, Alan O.

Differentiation ; 77(4): 424-32, 2009 Apr.

Artigo Inglês | MEDLINE | ID: mdl-19281789

10.

Introduction--Notch in development and disease.

Fortini, Mark E.

Semin Cell Dev Biol ; 23(4): 419-20, 2012 Jun.

Artigo Inglês | MEDLINE | ID: mdl-22425963

11.

Modeling clinically heterogeneous presenilin mutations with transgenic Drosophila.

Seidner, Glen A; Ye, Yihong; Faraday, Martha M; Alvord, W Gregory; Fortini, Mark E.

Curr Biol ; 16(10): 1026-33, 2006 May 23.

Artigo Inglês | MEDLINE | ID: mdl-16713961

12.

Nicastrin is required for gamma-secretase cleavage of the Drosophila Notch receptor.

Hu, Yue; Ye, Yihong; Fortini, Mark E.

Dev Cell ; 2(1): 69-78, 2002 Jan.

Artigo Inglês | MEDLINE | ID: mdl-11782315

13.

Different cofactor activities in gamma-secretase assembly: evidence for a nicastrin-Aph-1 subcomplex.

Hu, Yue; Fortini, Mark E.

J Cell Biol ; 161(4): 685-90, 2003 May 26.

Artigo Inglês | MEDLINE | ID: mdl-12771124

14.

A role for presenilin in post-stress regulation: effects of presenilin mutations on Ca2+ currents in Drosophila.

Lu, Yisheng; Lv, Yubing; Ye, Yihong; Wang, Yalin; Hong, Yu; Fortini, Mark E; Zhong, Yi; Xie, Zuoping.

FASEB J ; 21(10): 2368-78, 2007 Aug.

Artigo Inglês | MEDLINE | ID: mdl-17428965

15.

Notch signaling: a different sort makes the cut.

Kanwar, Ritu; Fortini, Mark E.

Curr Biol ; 14(24): R1043-5, 2004 Dec 29.

Artigo Inglês | MEDLINE | ID: mdl-15620635

16.

gamma-cleavage-independent functions of presenilin, nicastrin, and Aph-1 regulate cell-junction organization and prevent tau toxicity in vivo.

Dotti, Carlos G; Feiguin, Fabian; Fortini, Mark E.

Neuron ; 53(3): 463, 2007 Feb 01.

Artigo Inglês | MEDLINE | ID: mdl-17326324

17.

Neurobiology: double trouble for neurons.

Fortini, Mark E.

Nature ; 425(6958): 565-6, 2003 Oct 09.

Artigo Inglês | MEDLINE | ID: mdl-14534567

18.

Transcriptomic Analysis of Drosophila Mushroom Body Neurons Lacking Amyloid-ß Precursor-Like Protein Activity.

Khanna, Mansi R; Fortini, Mark E.

J Alzheimers Dis ; 46(4): 913-28, 2015.

Artigo Inglês | MEDLINE | ID: mdl-26402626

19.

In vivo reconstitution of gamma-secretase in Drosophila results in substrate specificity.

Stempfle, Denise; Kanwar, Ritu; Loewer, Alexander; Fortini, Mark E; Merdes, Gunter.

Mol Cell Biol ; 30(13): 3165-75, 2010 Jul.

Artigo Inglês | MEDLINE | ID: mdl-20421416

20.

Notch signaling: the core pathway and its posttranslational regulation.

Fortini, Mark E.

Dev Cell ; 16(5): 633-47, 2009 May.

Artigo Inglês | MEDLINE | ID: mdl-19460341

Secretaria de Estado da Saúde - BVS

Rede de Informação e Conhecimento

Sua seleção (0)

Formato de exportação:

Exportar:

The big brain aquaporin is required for endosome maturation and notch receptor trafficking.

Protein trafficking abnormalities in Drosophila tissues with impaired activity of the ZIP7 zinc transporter Catsup.

Disruption of Drosophila melanogaster lipid metabolism genes causes tissue overgrowth associated with altered developmental signaling.

Deficient Notch signaling associated with neurogenic pecanex is compensated for by the unfolded protein response in Drosophila.

Therapeutic approaches to modulating Notch signaling: current challenges and future prospects.

Pharmacological and genetic reversal of age-dependent cognitive deficits attributable to decreased presenilin function.

gamma-cleavage-independent functions of presenilin, nicastrin, and Aph-1 regulate cell-junction organization and prevent tau toxicity in vivo.

Pharmacological analysis of Drosophila melanogaster gamma-secretase with respect to differential proteolysis of Notch and APP.

Inheritance of susceptibility to induction of nephroblastomas in the Noble rat.

Introduction--Notch in development and disease.

Modeling clinically heterogeneous presenilin mutations with transgenic Drosophila.

Nicastrin is required for gamma-secretase cleavage of the Drosophila Notch receptor.

Different cofactor activities in gamma-secretase assembly: evidence for a nicastrin-Aph-1 subcomplex.

A role for presenilin in post-stress regulation: effects of presenilin mutations on Ca2+ currents in Drosophila.

Notch signaling: a different sort makes the cut.

gamma-cleavage-independent functions of presenilin, nicastrin, and Aph-1 regulate cell-junction organization and prevent tau toxicity in vivo.

Neurobiology: double trouble for neurons.

Transcriptomic Analysis of Drosophila Mushroom Body Neurons Lacking Amyloid-ß Precursor-Like Protein Activity.

In vivo reconstitution of gamma-secretase in Drosophila results in substrate specificity.

Notch signaling: the core pathway and its posttranslational regulation.