Detalhe da pesquisa
1.
Targeting the Actions of Muscarinic Receptors on Dopamine Systems: New Strategies for Treating Neuropsychiatric Disorders.
Annu Rev Pharmacol Toxicol
; 64: 277-289, 2024 Jan 23.
Artigo
Inglês
| MEDLINE | ID: mdl-37552895
2.
Ventral Tegmental Area M5 Muscarinic Receptors Mediate Effort-Choice Responding and Nucleus Accumbens Dopamine in a Sex-Specific Manner .
J Pharmacol Exp Ther
; 385(2): 146-156, 2023 05.
Artigo
Inglês
| MEDLINE | ID: mdl-36828630
3.
Activation of the mGlu1 metabotropic glutamate receptor has antipsychotic-like effects and is required for efficacy of M4 muscarinic receptor allosteric modulators.
Mol Psychiatry
; 25(11): 2786-2799, 2020 11.
Artigo
Inglês
| MEDLINE | ID: mdl-30116027
4.
Bile diversion, a bariatric surgery, and bile acid signaling reduce central cocaine reward.
PLoS Biol
; 16(7): e2006682, 2018 07.
Artigo
Inglês
| MEDLINE | ID: mdl-30048457
5.
High density is a property of slow-cycling and treatment-resistant human glioblastoma cells.
Exp Cell Res
; 378(1): 76-86, 2019 05 01.
Artigo
Inglês
| MEDLINE | ID: mdl-30844389
6.
Activity in LIP, But not V4, Matches Performance When Attention is Spread.
Cereb Cortex
; 28(12): 4195-4209, 2018 12 01.
Artigo
Inglês
| MEDLINE | ID: mdl-29069324
7.
Allosteric activation of M4 muscarinic receptors improve behavioral and physiological alterations in early symptomatic YAC128 mice.
Proc Natl Acad Sci U S A
; 112(45): 14078-83, 2015 Nov 10.
Artigo
Inglês
| MEDLINE | ID: mdl-26508634
8.
M5 receptor activation produces opposing physiological outcomes in dopamine neurons depending on the receptor's location.
J Neurosci
; 34(9): 3253-62, 2014 Feb 26.
Artigo
Inglês
| MEDLINE | ID: mdl-24573284
9.
LIP activity in the interstimulus interval of a change detection task biases the behavioral response.
J Neurophysiol
; 114(5): 2637-48, 2015 Nov.
Artigo
Inglês
| MEDLINE | ID: mdl-26334012
10.
Activation of Metabotropic Glutamate Receptor 3 Modulates Thalamo-accumbal Transmission and Rescues Schizophrenia-like Physiological and Behavioral Deficits.
Biol Psychiatry
; 2023 Dec 05.
Artigo
Inglês
| MEDLINE | ID: mdl-38061467
11.
Muscarinic receptors: from clinic to bench to clinic.
Trends Pharmacol Sci
; 43(6): 461-463, 2022 06.
Artigo
Inglês
| MEDLINE | ID: mdl-35101279
12.
Cannabinoid type-2 receptors: An emerging target for regulating schizophrenia-relevant brain circuits.
Front Neurosci
; 16: 925792, 2022.
Artigo
Inglês
| MEDLINE | ID: mdl-36033626
13.
A retrospective observational study of patient analgesia outcomes when regional anaesthesia procedures are performed by consultants versus supervised trainees.
Anaesth Intensive Care
; 50(3): 197-203, 2022 May.
Artigo
Inglês
| MEDLINE | ID: mdl-35301865
14.
Sphingosine Kinase 2 Inhibitors: Rigid Aliphatic Tail Derivatives Deliver Potent and Selective Analogues.
ACS Bio Med Chem Au
; 2(5): 469-489, 2022 Oct 19.
Artigo
Inglês
| MEDLINE | ID: mdl-36281302
15.
mGlu1-mediated restoration of prefrontal cortex inhibitory signaling reverses social and cognitive deficits in an NMDA hypofunction model in mice.
Neuropsychopharmacology
; 47(10): 1826-1835, 2022 09.
Artigo
Inglês
| MEDLINE | ID: mdl-35643819
16.
Development of VU6019650: A Potent, Highly Selective, and Systemically Active Orthosteric Antagonist of the M5 Muscarinic Acetylcholine Receptor for the Treatment of Opioid Use Disorder.
J Med Chem
; 65(8): 6273-6286, 2022 04 28.
Artigo
Inglês
| MEDLINE | ID: mdl-35417155
17.
Targeting muscarinic receptors to treat schizophrenia.
Behav Brain Res
; 405: 113201, 2021 05 07.
Artigo
Inglês
| MEDLINE | ID: mdl-33647377
18.
Genome-wide CRISPR interference screen identifies long non-coding RNA loci required for differentiation and pluripotency.
PLoS One
; 16(11): e0252848, 2021.
Artigo
Inglês
| MEDLINE | ID: mdl-34731163
19.
Discovery of the First Selective M4 Muscarinic Acetylcholine Receptor Antagonists with in Vivo Antiparkinsonian and Antidystonic Efficacy.
ACS Pharmacol Transl Sci
; 4(4): 1306-1321, 2021 Aug 13.
Artigo
Inglês
| MEDLINE | ID: mdl-34423268
20.
Receptor regulation of osmolyte homeostasis in neural cells.
J Physiol
; 588(Pt 18): 3355-64, 2010 Sep 15.
Artigo
Inglês
| MEDLINE | ID: mdl-20498228