RESUMO
Radopholus Similis (R. Similis) or burrowing nematode, is one of the most damaging and widespread nematodes attacking bananas, causing toppling or blackhead disease. A mathematical model for the population dynamics of R. Similis is considered, with the aim of investigating the impact of climatic factors on the growth of R. Similis. In this paper, based on the life cycle of R. Similis, we first propose a mathematical model to study and control the population dynamics of this banana pest. We show also how control terms based on biological and chemical controls can be integrated to reduce the population of R. Similis within banana-plantain roots. Sensitivity analysis was performed to show the most important parameters of the model. We present the theoretical analysis of the model. More precisely, we derive a threshold parameter [Formula: see text], called the basic offspring number and show that the trivial equilibrium is globally asymptotically stable whenever [Formula: see text], while when [Formula: see text], the non trivial equilibrium is globally asymptotically stable. After, we extend the proposed model by taking account climatic factors that influence the growth of this pest. Biological and chemical controls are now introduced through impulsive equations. Threshold and equilibria are obtained and global stabilities have been studied. The theoretical results are supported by numerical simulations. Numerical results of model with biological and chemical controls reveal that biological methods are more effective than chemical methods. We also found that the month February is the best time to apply these controls.
Assuntos
Musa , Plantago , Tylenchoidea , Animais , Raízes de Plantas , Dinâmica PopulacionalRESUMO
Entamoeba histolytica, is a human pathogen which is endemic in tropical areas. The most common extra-intestinal locations for disease after the liver are pleural and pulmonary. Although the outcome of pleural and pulmonary amoebiasis is generally favourable, it is important to note that a significant proportion of patients do develop pleural and pulmonary after-effects. We report a case of pleural and pulmonary amoebiasis where the evolution of a massive pleural effusion and 3 associated liver abscesses was spectacular. The surgical management of pleural, pulmonary and liver amoebiasis is discussed.
Assuntos
Entamoeba histolytica , Entamebíase/diagnóstico , Abscesso Hepático Amebiano/diagnóstico , Pneumopatias Parasitárias/diagnóstico , Derrame Pleural/parasitologia , Adulto , Animais , Antibacterianos/uso terapêutico , Antiprotozoários/uso terapêutico , Diagnóstico Diferencial , Quimioterapia Combinada , Entamoeba histolytica/isolamento & purificação , Entamebíase/tratamento farmacológico , Entamebíase/parasitologia , Humanos , Abscesso Hepático Amebiano/tratamento farmacológico , Abscesso Hepático Amebiano/parasitologia , Pneumopatias Parasitárias/tratamento farmacológico , Pneumopatias Parasitárias/parasitologia , Masculino , Metronidazol/uso terapêutico , Derrame Pleural/diagnóstico , Resultado do TratamentoRESUMO
A new sulfur-containing guanidino derivative, halichondria sulfonic acid (1) showing anti-HIV-1 activity, and halistanol trisulfate (2) with anti-tumor activity have been isolated from the marine sponge Halichondria rugosa Ridley & Dendy collected in the Chinese Southern Sea. The structure of 1 was elucidated by analysis of spectroscopic and crystal data.
Assuntos
Fármacos Anti-HIV/química , Guanidinas/química , HIV-1/efeitos dos fármacos , Poríferos/química , Esteróis/química , Ácidos Sulfônicos/química , Animais , Fármacos Anti-HIV/isolamento & purificação , Fármacos Anti-HIV/toxicidade , Linhagem Celular , Sobrevivência Celular/efeitos dos fármacos , China , Cristalografia por Raios X , Ensaio de Imunoadsorção Enzimática , Guanidinas/isolamento & purificação , Guanidinas/toxicidade , Concentração Inibidora 50 , Estrutura Molecular , Oceanos e Mares , Espectrofotometria Infravermelho , Análise Espectral , Esteróis/isolamento & purificação , Esteróis/toxicidade , Ácidos Sulfônicos/isolamento & purificação , Ácidos Sulfônicos/toxicidade , Sais de Tetrazólio , TiazóisRESUMO
The present study was designed to assess the value of self reported hematuria and dysuria in the diagnosis of urinary schistosomiasis at the individual level. A sample of 964 school children of grade 5 and 6 from 15 schools of the French speaking educational system in the Sudano-sahelian zone of northern Cameroon were submitted to a questionnaire related to hematuria and dysuria; and provided a urine sample each. The urine samples were processed using the dip stick and sedimentation methods; and the degree of microhematuria and oviuria determined. In all 964 questionnaires were collected; 843 urine samples examined for microhematuria and 871 for oviuria. The percentage of children reporting hematuria increased with the degree of microhematuria and the intensity of infection. Among the various indicators of urinary schistosome infection; microhematuria had the highest sensitivity (76); followed by self reported hematuria or dysuria (65); and dysuria (52). The specificity was highest for self reported hematuria; and lowest for self reported hematuria or dysuria. The efficiency of self reported hematuria or dysuria increased with the intensity of infection and was highest (100) for heavy infections ( 400 eggs/ml g urine). We advocate the use of self reported hematuria or dysuria for the assessment of S. haematobium at the individual level