Detalhe da pesquisa
1.
Wastewater-based surveillance as a tool for public health action: SARS-CoV-2 and beyond.
Clin Microbiol Rev
; 37(1): e0010322, 2024 03 14.
Artigo
Inglês
| MEDLINE | ID: mdl-38095438
2.
A Bayesian framework for modeling COVID-19 case numbers through longitudinal monitoring of SARS-CoV-2 RNA in wastewater.
Stat Med
; 43(6): 1153-1169, 2024 Mar 15.
Artigo
Inglês
| MEDLINE | ID: mdl-38221776
3.
Surveillance for SARS-CoV-2 and its variants in wastewater of tertiary care hospitals correlates with increasing case burden and outbreaks.
J Med Virol
; 95(2): e28442, 2023 02.
Artigo
Inglês
| MEDLINE | ID: mdl-36579780
4.
Tracking Emergence and Spread of SARS-CoV-2 Omicron Variant in Large and Small Communities by Wastewater Monitoring in Alberta, Canada.
Emerg Infect Dis
; 28(9): 1770-1776, 2022 09.
Artigo
Inglês
| MEDLINE | ID: mdl-35867051
5.
Divergent Electrochemical Carboamidation of Cyclic Amines.
J Org Chem
; 87(2): 1173-1193, 2022 01 21.
Artigo
Inglês
| MEDLINE | ID: mdl-34985905
6.
Development of pyrimidone D1 dopamine receptor positive allosteric modulators.
Bioorg Med Chem Lett
; 31: 127696, 2021 01 01.
Artigo
Inglês
| MEDLINE | ID: mdl-33221389
7.
Discovery of sultam-containing small-molecule disruptors of the huntingtin-calmodulin protein-protein interaction.
Med Chem Res
; 29(7): 1187-1198, 2020 Jul.
Artigo
Inglês
| MEDLINE | ID: mdl-33642842
8.
Identification of Positive Allosteric Modulators of the D1 Dopamine Receptor That Act at Diverse Binding Sites.
Mol Pharmacol
; 94(4): 1197-1209, 2018 10.
Artigo
Inglês
| MEDLINE | ID: mdl-30068735
9.
Synthesis of Kappa Opioid Antagonists Based On Pyrrolo[1,2-α]quinoxalinones Using an N-Arylation/Condensation/Oxidation Reaction Sequence.
J Org Chem
; 81(21): 10538-10550, 2016 11 04.
Artigo
Inglês
| MEDLINE | ID: mdl-27399050
10.
Decahydrobenzoquinolin-5-one sigma receptor ligands: Divergent development of both sigma 1 and sigma 2 receptor selective examples.
Bioorg Med Chem Lett
; 26(23): 5689-5694, 2016 12 01.
Artigo
Inglês
| MEDLINE | ID: mdl-27839919
11.
Potency enhancement of the κ-opioid receptor antagonist probe ML140 through sulfonamide constraint utilizing a tetrahydroisoquinoline motif.
Bioorg Med Chem
; 23(14): 3948-56, 2015 Jul 15.
Artigo
Inglês
| MEDLINE | ID: mdl-25593096
12.
Practical Electrochemical Anodic Oxidation of Polycyclic Lactams for Late Stage Functionalization.
Angew Chem Int Ed Engl
; 54(36): 10555-8, 2015 Sep 01.
Artigo
Inglês
| MEDLINE | ID: mdl-26371961
13.
Chemotype-selective modes of action of κ-opioid receptor agonists.
J Biol Chem
; 288(48): 34470-83, 2013 Nov 29.
Artigo
Inglês
| MEDLINE | ID: mdl-24121503
14.
Primuline derivatives that mimic RNA to stimulate hepatitis C virus NS3 helicase-catalyzed ATP hydrolysis.
J Biol Chem
; 288(27): 19949-57, 2013 Jul 05.
Artigo
Inglês
| MEDLINE | ID: mdl-23703611
15.
Development of functionally selective, small molecule agonists at kappa opioid receptors.
J Biol Chem
; 288(51): 36703-16, 2013 Dec 20.
Artigo
Inglês
| MEDLINE | ID: mdl-24187130
16.
Identification and analysis of hepatitis C virus NS3 helicase inhibitors using nucleic acid binding assays.
Nucleic Acids Res
; 40(17): 8607-21, 2012 Sep 01.
Artigo
Inglês
| MEDLINE | ID: mdl-22740655
17.
Synthesis and receptor profiling of Stemona alkaloid analogues reveal a potent class of sigma ligands.
Proc Natl Acad Sci U S A
; 108(17): 6727-32, 2011 Apr 26.
Artigo
Inglês
| MEDLINE | ID: mdl-21368188
18.
Wastewater surveillance monitoring of SARS-CoV-2 variants of concern and dynamics of transmission and community burden of COVID-19.
Emerg Microbes Infect
; 12(2): 2233638, 2023 Dec.
Artigo
Inglês
| MEDLINE | ID: mdl-37409382
19.
Wastewater-based surveillance can be used to model COVID-19-associated workforce absenteeism.
Sci Total Environ
; 900: 165172, 2023 Nov 20.
Artigo
Inglês
| MEDLINE | ID: mdl-37379934
20.
Campus node-based wastewater surveillance enables COVID-19 case localization and confirms lower SARS-CoV-2 burden relative to the surrounding community.
Water Res
; 244: 120469, 2023 Oct 01.
Artigo
Inglês
| MEDLINE | ID: mdl-37634459