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1.
Diabetes Spectr ; 37(2): 124-129, 2024.
Artigo em Inglês | MEDLINE | ID: mdl-38756425

RESUMO

Objective: The aim of this study was to assess the extent of nondisclosure of type 1 diabetes in adolescents and investigate its association with several psychosocial parameters and clinical outcomes. Research design and methods: This was a cross-sectional study based on data collected from 69 adolescents with type 1 diabetes who were 12-18 years of age and followed at our diabetes clinic. The degree of disclosure, demographics, diabetes management, and psychosocial issues were assessed via questionnaires. Clinical parameters were derived from medical records. Associations between nondisclosure status and clinical and psychosocial study variables were assessed. Results: Fifty-three participants (77%) reported some extent of nondisclosure. Nondisclosure was associated with low self-esteem, reduced friend support, and increased diabetes-related worries. Nondisclosure was also found to be associated with diminished self-care behaviors related to insulin administration and with elevated A1C. Conclusion: Our results demonstrate that nondisclosure of type 1 diabetes in adolescents may be more common than initially recognized and is likely associated with unfavorable psychological outcomes and reduced self-care and diabetes management. Our results emphasize the importance of social interactions and disclosure in adolescents and may serve as a potential stepping stone to address other social barriers hindering diabetes management.

2.
Eur J Nutr ; 60(1): 65-77, 2021 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-32185478

RESUMO

PURPOSE: Studies of the association between maternal nutrition and birth outcomes have investigated differing nutrients, maternal socioeconomic conditions, and timing within the reproductive cycle; and have produced inconsistent results. We evaluated the association of preconceptional maternal dietary intake with birth outcomes among low socioeconomic status ethnic minority women in a high-income country. METHODS: In this prospective cohort study, habitual preconceptional dietary intake was assessed among pregnant Bedouin Arab women in Israel (n = 384), using a short culturally specific, targeted food frequency questionnaire. Multiple nutrients (protein, lysine, calcium, iron, zinc, folate, omega-3 fatty acids) were evaluated simultaneously via a diet quality score derived from principal component analysis. Multivariable logistic regression was used to test associations between the diet quality score and a composite adverse birth outcomes variable, including preterm birth, low birth weight and small for gestational age. RESULTS: Sixty-nine women (18%) had adverse birth outcomes. Women with low preconceptional diet quality scores had low intakes of nutrient-rich plant foods, bioavailable micronutrients, and complete proteins. In multivariable analysis, a woman at the 10th percentile of the diet quality score had a 2.97 higher odds (95% CI 1.28-6.86) of an adverse birth outcome than a woman at the 90th percentile. CONCLUSION: Low diet quality during the preconceptional period was associated with adverse birth outcomes among low socioeconomic status minority women in a high-income country. The results have implications for the development of appropriate intervention strategies to prevent adverse birth outcomes, and the promotion of adequate nutrition throughout the child-bearing years.


Assuntos
Nascimento Prematuro , Peso ao Nascer , Dieta , Etnicidade , Feminino , Humanos , Recém-Nascido , Grupos Minoritários , Gravidez , Nascimento Prematuro/epidemiologia , Estudos Prospectivos , Classe Social
3.
J Antimicrob Chemother ; 70(11): 3146-53, 2015 Nov.
Artigo em Inglês | MEDLINE | ID: mdl-26209312

RESUMO

OBJECTIVES: Carbapenem-resistant Gram-negative bacteria (CRGNB) pose a clinical challenge. We attempted to estimate the mortality burden of CRGNB among haematological cancer patients. METHODS: This was a retrospective cohort study. We included adult patients hospitalized in the haemato-oncological/bone marrow transplantation departments for chemotherapy, between 2008 and 2014, with Gram-negative aerobic bacteraemia. We compared patients with CRGNB and carbapenem-susceptible Gram-negative bacteraemia (CSGNB). The primary outcome was 14 day all-cause mortality. In addition, we assessed 1 year survival. Multivariable logistics regression analysis and adjusted Cox regression analysis were conducted. Analyses were adjusted to the propensity for CRGNB bacteraemia. RESULTS: The cohort included mostly young patients (mean age 50.1 years) with acute leukaemia (264/423, 62.4%) and the median absolute neutrophil count at bacteraemia onset was 0 × 10(9)/L. The unadjusted 14 day mortality rate was higher for patients with CRGNB compared with CSGNB [45.6% (47/103) versus 15% (48/320), respectively (P < 0.001)]. Adjusting to baseline prognostic factors, infection characteristics and the propensity score retained a significant association between CRGNB and 14 day mortality (OR 5.14, 95% CI 2.32-11.38). Including only the first bacteraemic episode per patient, 1 year mortality was 74.7% (68/91) for patients with CRGNB versus 49.8% (119/239) for patients with CSGNB (P < 0.001). Adjusting for risk factors associated with 1 year mortality, the HR for mortality with CRGNB was 1.48 (95% CI 1-2.2). CRGNB bacteraemia was associated with several risk factors for mortality, including inappropriate empirical antibiotic treatment and less effective definitive antibiotics. CONCLUSIONS: This study demonstrated a significant adjusted association between CRGNB and mortality up to 1 year among haemato-oncological patients receiving chemotherapy.


Assuntos
Antibacterianos/farmacologia , Bacteriemia/mortalidade , Carbapenêmicos/farmacologia , Bactérias Gram-Negativas/efeitos dos fármacos , Infecções por Bactérias Gram-Negativas/mortalidade , Neoplasias Hematológicas/complicações , Adulto , Idoso , Bacteriemia/microbiologia , Estudos de Coortes , Feminino , Bactérias Gram-Negativas/isolamento & purificação , Infecções por Bactérias Gram-Negativas/microbiologia , Humanos , Masculino , Pessoa de Meia-Idade , Estudos Retrospectivos , Análise de Sobrevida , Resistência beta-Lactâmica
4.
Isr Med Assoc J ; 16(7): 434-8, 2014 Jul.
Artigo em Inglês | MEDLINE | ID: mdl-25167690

RESUMO

BACKGROUND: A high prevalence of iron deficiency anemia persists in Bedouin Arab and Jewish pediatric populations in southern Israel. OBJECTIVES: To compare the effect of daily use of the micronutrient supplementation (MMS), "Sprinkles," a powdered formulation of iron, vitamins A and C, folic acid and zinc, with liquid iron and vitamins A and D on iron deficiency at 12 months of age. METHODS: The 621 eligible Bedouin and Jewish infants in the study were assigned to the MMS and control arms and received supplementations from age 6 to 12 months. We examined the change in hemoglobin, hematocrit, mean cell volume, red blood cell distribution, serum ferritin and transferrin saturation. In addition, we used the high Iron Deficiency Index (IDI) if two or more of the above six parameters showed abnormal levels. RESULTS: Rates of anemia decreased significantly over the 6 month period, from 58.8% to 40.6% among Bedouin infants (P = 0.037) and from 40.6 to 15.8% among Jewish infants (P = 0.017). In Bedouin infants the prevalence of high IDI decreased significantly from 79.2% to 67.4% (P = 0.010) in the MMS group, but there was no change in the controls. Among Jewish infants, the high IDI prevalence decreased from 67% to 55.6% with no statistically significant difference in the two study arms. In the multivariate analysis in Bedouin infants MMS use was associated with a reduced risk of 67% in high IDI at age 12 months as compared to controls (P = 0.001). Fewer side effects in the intervention groups in both ethnic populations were reported. CONCLUSIONS: MMS fortification of home food can be recommended as an effective and safe method for preventing iron deficiency anemia at 12 months of age.


Assuntos
Anemia Ferropriva/etnologia , Anemia Ferropriva/prevenção & controle , Árabes/estatística & dados numéricos , Suplementos Nutricionais , Judeus/estatística & dados numéricos , Micronutrientes/administração & dosagem , Anemia Ferropriva/epidemiologia , Feminino , Hematócrito , Humanos , Lactente , Alimentos Infantis , Israel/epidemiologia , Masculino , Estado Nutricional/etnologia , Fatores Socioeconômicos
5.
Depress Anxiety ; 30(5): 425-31, 2013 May.
Artigo em Inglês | MEDLINE | ID: mdl-23620192

RESUMO

BACKGROUND: The prevalence and manifestation of posttraumatic stress symptoms in young children may differ from that observed in adults. This study examined sociodemographic, familial, and psychosomatic correlates of posttraumatic stress disorder (PTSD) among preschool children and their mothers who had been exposed to ongoing missile attacks in the Gaza war. METHODS: One hundred and sixty-seven mothers of preschoolers (aged 4.0-6.5 years) were interviewed regarding PTSD and psychosomatic symptomatology of their children, as well as their own reactions to trauma. RESULTS: Fourteen mothers (8.4%) and 35 children (21.0%) screened positive for PTSD. Sociodemographic characteristics were not associated with PTSD among mothers or children. Among children, the only significant risk factor was having a mother with PTSD (OR = 12.22, 95% CI 2.75-54.28). Compared to children who did not screen positive for PTSD, those who did screen positive displayed significantly higher rates of psychosomatic reactions to trauma, most notably constipation or diarrhea (OR = 4.36, 95% CI 1.64-11.60) and headaches (OR = 2.91, 95% CI 1.07-7.94). CONCLUSIONS: Results of this study add to the burgeoning literature on child PTSD, emphasizing the important role of maternal anxiety and the psychosomatic reactions associated with exposure to ongoing traumatic experiences in young children.


Assuntos
Mães/psicologia , Transtornos de Estresse Pós-Traumáticos/epidemiologia , Guerra , Adulto , Criança , Pré-Escolar , Constipação Intestinal/epidemiologia , Constipação Intestinal/psicologia , Diarreia/epidemiologia , Diarreia/psicologia , Feminino , Cefaleia/epidemiologia , Cefaleia/psicologia , Humanos , Israel/epidemiologia , Masculino , Oriente Médio , Transtornos Somatoformes/epidemiologia
6.
Ethn Dis ; 23(3): 329-35, 2013.
Artigo em Inglês | MEDLINE | ID: mdl-23914419

RESUMO

OBJECTIVE: To examine the relationship between acculturation and obesity among low socioeconomic status (LSES) children. DESIGN: Cross-sectional study. SETTING: Children from 12 preschools in LSES neighborhoods were recruited. PARTICIPANTS: Anthropometric measurements were obtained from 238 children (aged 4-7 years) and 224 mothers. Sociodemographic characteristics and perceptions of child's weight were collected from mothers. We compared native Israelis and immigrants for risk factors for obesity, using a 9-year cut-off to define new and acculturated immigrants. RESULTS: The combined prevalence of overweight and obesity (OWOB) among children was 29.8% (71/238) using the World Health Organization (WHO) growth standard. Mean age, sleeping hours, sex distribution and poverty level were similar between immigrants and natives. Prevalence of OWOB and current parental smoking were significantly lower among children of new immigrants (P = .02). More than 82% of mothers underestimated their child's weight status, 74.2% of OWOB children were perceived as normal-weight (NW) and 8% as thin. In a multivariable logistic-regression analysis comparing NW to OWOB children, maternal underestimation of the child's weight status (OR = 7.5; 95%CI: 3.4-16.5, P < .0001) and being born to acculturated immigrants (OR = 2.3 95% CI: 1.1-4.7, P = .03) were associated with OWOB. Ethiopian children were at lower risk for obesity. Paternal smoking increased the risk for obesity by 2-fold in non-Ethiopian, and 5-fold in Ethiopian children (OR = 2.0 and 5.0, respectively; P for interaction = .026). CONCLUSIONS: Acculturation, perception of child's weight status and parental smoking are associated with childhood OWOB. Immigration status should be considered when programs to prevent childhood obesity are implemented in mixed populations.


Assuntos
Emigrantes e Imigrantes/estatística & dados numéricos , Mães , Obesidade/etnologia , Fumar/etnologia , Aculturação , Adulto , Peso Corporal , Criança , Pré-Escolar , Intervalos de Confiança , Estudos Transversais , Escolaridade , Etiópia/etnologia , Pai , Feminino , Humanos , Israel/epidemiologia , Modelos Logísticos , Masculino , Pessoa de Meia-Idade , Análise Multivariada , Razão de Chances , Sobrepeso/etnologia , Percepção , Pobreza , Prevalência , Fatores de Risco , Adulto Jovem
7.
Br J Nutr ; 108(10): 1874-83, 2012 Nov 28.
Artigo em Inglês | MEDLINE | ID: mdl-22264559

RESUMO

Bedouin Arabs in southern Israel are a traditionally semi-nomadic population undergoing the nutrition transition in a context of urbanisation. The effect of these changes on the nutritional status of pregnant women is unknown. The Dietary Exposures and Pregnancy Outcomes in a Society In Transition (DEPOSIT) study evaluated the adequacy of pregnant Bedouin women's usual dietary intake and their nutritional status. Dietary intake was assessed in a cross-sectional study design using repeat 24 h recall (24HR) questionnaires. The National Cancer Institute method was used to estimate the usual intake of selected nutrients. The Estimated Average Requirement (EAR) was used to evaluate nutrient intake adequacy. Measured weight and height data were used to calculate the participants' BMI. A total of 1109 24HR were obtained from 683 participants, of which 8 % contained no animal-source protein and an additional 43 % contained no haeme-Fe. Animal-source protein intake reached less than half of the EAR for most participants (71 %). Over 90 % had inadequate intakes of Ca, Fe, animal-source Zn, vitamin A and folate. The probability of consuming haeme-source Fe was higher among urban than rural participants (OR 1·68, 95 % CI 1·17, 2·41), and among those with employed v. unemployed husbands (OR 1·81, 95 % CI 1·27, 2·58). Only 14 % reported consuming home-produced animal products. According to pre-pregnancy BMI, 42 % were overweight or obese. The DEPOSIT study findings suggest that Bedouin Arab women are in need of interventions that address the co-existing problems of inadequate nutrient intakes and increased risk of obesity.


Assuntos
Ingestão de Alimentos/fisiologia , Fenômenos Fisiológicos da Nutrição Materna , Estado Nutricional/fisiologia , Adulto , Árabes , Inquéritos sobre Dietas , Ingestão de Energia , Comportamento Alimentar , Feminino , Análise de Alimentos , Humanos , Micronutrientes , Gravidez , População Rural , Fatores Socioeconômicos , Adulto Jovem
8.
N Engl J Med ; 359(3): 229-41, 2008 Jul 17.
Artigo em Inglês | MEDLINE | ID: mdl-18635428

RESUMO

BACKGROUND: Trials comparing the effectiveness and safety of weight-loss diets are frequently limited by short follow-up times and high dropout rates. METHODS: In this 2-year trial, we randomly assigned 322 moderately obese subjects (mean age, 52 years; mean body-mass index [the weight in kilograms divided by the square of the height in meters], 31; male sex, 86%) to one of three diets: low-fat, restricted-calorie; Mediterranean, restricted-calorie; or low-carbohydrate, non-restricted-calorie. RESULTS: The rate of adherence to a study diet was 95.4% at 1 year and 84.6% at 2 years. The Mediterranean-diet group consumed the largest amounts of dietary fiber and had the highest ratio of monounsaturated to saturated fat (P<0.05 for all comparisons among treatment groups). The low-carbohydrate group consumed the smallest amount of carbohydrates and the largest amounts of fat, protein, and cholesterol and had the highest percentage of participants with detectable urinary ketones (P<0.05 for all comparisons among treatment groups). The mean weight loss was 2.9 kg for the low-fat group, 4.4 kg for the Mediterranean-diet group, and 4.7 kg for the low-carbohydrate group (P<0.001 for the interaction between diet group and time); among the 272 participants who completed the intervention, the mean weight losses were 3.3 kg, 4.6 kg, and 5.5 kg, respectively. The relative reduction in the ratio of total cholesterol to high-density lipoprotein cholesterol was 20% in the low-carbohydrate group and 12% in the low-fat group (P=0.01). Among the 36 subjects with diabetes, changes in fasting plasma glucose and insulin levels were more favorable among those assigned to the Mediterranean diet than among those assigned to the low-fat diet (P<0.001 for the interaction among diabetes and Mediterranean diet and time with respect to fasting glucose levels). CONCLUSIONS: Mediterranean and low-carbohydrate diets may be effective alternatives to low-fat diets. The more favorable effects on lipids (with the low-carbohydrate diet) and on glycemic control (with the Mediterranean diet) suggest that personal preferences and metabolic considerations might inform individualized tailoring of dietary interventions. (ClinicalTrials.gov number, NCT00160108.)


Assuntos
Dieta com Restrição de Carboidratos , Dieta com Restrição de Gorduras , Dieta Mediterrânea , Obesidade/dietoterapia , Biomarcadores/sangue , Glicemia/análise , Índice de Massa Corporal , Ingestão de Energia , Feminino , Seguimentos , Hemoglobinas Glicadas/análise , Humanos , Cetonas/urina , Lipídeos/sangue , Masculino , Pessoa de Meia-Idade , Obesidade/sangue , Obesidade/urina , Inquéritos e Questionários , Redução de Peso
9.
J Am Coll Nutr ; 30(6): 491-501, 2011 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-22331684

RESUMO

BACKGROUND: Distinct weight loss dietary strategies are associated with changes in specific food groups. OBJECTIVE: To address the effect of changes in specific weight of food groups on weight loss in a 2-year low-fat, Mediterranean, low-carbohydrate intervention trial (DIRECT). METHODS: We assessed changes in the intake of 12 food groups among 322 participants (body mass index [BMI] = 31 kg/m(2); age = 52 years; 86% men), using a validated electronic food frequency questionnaire. RESULTS: The weight of the 3592.9 ± 1558 (g/d ± SD) of baseline food consumed consisted mainly of liquids, excluding water (32.6% of total weight of food); vegetables (18.8%), fruits (17.7%), dairy (9.0%), meat (7.7%), and bread/cereal/pasta/potatoes (7.1%). Participants significantly reduced food intake by 283.73 ± 1342 (g/d ± SD) at 6 months and by 963.36 ± 1869 (g/d ± SD) at 24 months (p < 0.05 as compared with baseline). Food weight changes were similar across diet groups (p = 0.366), whereas 6-month body weight loss was -4.6 ± 4.4 kg, -4.7 ± 4.9 kg, and -6.4 ± 6.6 kg for low-fat, Mediterranean, and low-carbohydrate groups, respectively; p < 0.026). In multivariate regression models, adjusted for age, sex, baseline body weight, and changes in weight intake of 12 food groups (g/d), independent dietary predictors (standardized-ß) at 6 months (rapid weight loss phase) were as follows: decreased consumption of sweets and cakes (ß = 0.493; p = 0.008) in the low-fat group, tendency toward increased crude legumes (ß = -0.196; p = 0.061) in the Mediterranean group, and increased vegetable intake (ß = -0.249; p = 0.018) in the low-carbohydrate diet group. In the entire group, in models further adjusted for diet type, leading predictors for rapid weight loss phase were as follows: increased vegetables by ~140 g/d (ß = -0.116; p = 0.045) and decreased intake of sweets and cakes by ~30 g/d (ß = 0.162; p = 0.010). Universal predictors for 2-year successful weight loss in the entire group were as follows: increased intake of vegetables (ß = -0.192; p = 0.007) and meat (ß = -0.146; p = 0.026) and decreased intake of eggs (ß = 0.187; p = 0.003), processed legumes (ß = 0.195; p = 0.002), and beverages (ß = 0.135; p = 0.032). CONCLUSIONS: Two-year weight loss is associated with a decrease of ~1 kg of total food consumed and may be achieved by a variety of changes in specific food groups within different diet strategies. Universal predictors of successful weight loss in the rapid weight loss phase across all diet strategies are increasing the weight of intake of vegetables and decreasing the weight of intake of sweets and cakes.


Assuntos
Dieta com Restrição de Carboidratos , Dieta com Restrição de Gorduras , Dieta Mediterrânea , Ingestão de Energia , Redução de Peso , Adulto , Composição Corporal , Índice de Massa Corporal , Comportamento Alimentar , Feminino , Frutas , Humanos , Israel , Modelos Lineares , Masculino , Carne , Pessoa de Meia-Idade , Análise Multivariada , Cooperação do Paciente , Inquéritos e Questionários , Verduras
10.
Public Health Nutr ; 14(3): 379-87, 2011 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-20519048

RESUMO

OBJECTIVE: To develop a targeted FFQ (TFFQ) and evaluate its effectiveness for ranking minority women by their intake of multiple nutrients important to a healthy pregnancy. DESIGN: In Stage 1, food groups derived from 24 h recall dietary data were entered into a stepwise multiple regression model to identify 'discriminating' foods for the TFFQ; in Stage 2, the TFFQ and a 24 h recall were administered to pregnant women. The TFFQ data were used to create a Habitual Multi-Nutrient Intake Scale (H-MNIS) for ranking the women. The effectiveness of the ranking was tested against women's reported nutrient intakes on the 24 h recall. SETTING: Southern Israel. SUBJECTS: In Stage 1, 519 Bedouin Arab adults; in Stage 2, 404 pregnant Bedouin women. RESULTS: Of the ninety-three food groups included in the regression analysis, twenty-eight explained >80 % of the between-person variability in the intake of the target nutrients. Whole-wheat bread was a main discriminator for protein, Fe, Zn, Ca and folate. Fish, poultry and canned tuna explained ≥88 % of the between-person variation in DHA and EPA intakes. The mean daily intakes of pregnant Bedouin women from the 24 h recall data differed significantly across H-MNIS quartiles (P < 0·01) for all but three target nutrients (folate, EPA, DHA); and the P for trend was significant (P < 0·02) for all but EPA. CONCLUSIONS: The TFFQ and H-MNIS represent rapid assessment tools for studying maternal nutrition on a multi-nutrient basis, and effectively ranked pregnant Bedouin women into exposure groups by their intake of the target nutrients.


Assuntos
Árabes , Comportamento Alimentar , Grupos Minoritários , Gravidez , Adulto , Estudos Transversais , Dieta , Registros de Dieta , Inquéritos sobre Dietas , Ácidos Docosa-Hexaenoicos/administração & dosagem , Ácido Eicosapentaenoico/administração & dosagem , Ingestão de Energia , Feminino , Ácido Fólico/administração & dosagem , Humanos , Israel , Fenômenos Fisiológicos da Nutrição Materna , Avaliação Nutricional , Projetos Piloto , Análise de Regressão , Fatores Socioeconômicos , Inquéritos e Questionários , Adulto Jovem
11.
Epidemiol Rev ; 32: 5-25, 2010.
Artigo em Inglês | MEDLINE | ID: mdl-20237078

RESUMO

In this review, the authors summarize current knowledge on maternal nutritional requirements during pregnancy, with a focus on the nutrients that have been most commonly investigated in association with birth outcomes. Data sourcing and extraction included searches of the primary resources establishing maternal nutrient requirements during pregnancy (e.g., Dietary Reference Intakes), and searches of Medline for "maternal nutrition"/[specific nutrient of interest] and "birth/pregnancy outcomes," focusing mainly on the less extensively reviewed evidence from observational studies of maternal dietary intake and birth outcomes. The authors used a conceptual framework which took both primary and secondary factors (e.g., baseline maternal nutritional status, socioeconomic status of the study populations, timing and methods of assessing maternal nutritional variables) into account when interpreting study findings. The authors conclude that maternal nutrition is a modifiable risk factor of public health importance that can be integrated into efforts to prevent adverse birth outcomes, particularly among economically developing/low-income populations.


Assuntos
Bem-Estar Materno , Estado Nutricional , Resultado da Gravidez , Feminino , Humanos , Gravidez , Ensaios Clínicos Controlados Aleatórios como Assunto , Classe Social
12.
J Pediatr Gastroenterol Nutr ; 50(2): 173-8, 2010 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-19668004

RESUMO

OBJECTIVES: Patients with cystic fibrosis (CF) presenting with meconium ileus (MI) tend to have worse outcomes than those without MI. We evaluated the clinical characteristics and survival rates among Israeli patients with CF with and without MI after a prolonged follow-up (15-30 years). PATIENTS AND METHODS: A multicenter retrospective study. Forty-nine patients with CF, representing 13.8% of all patients with CF in Israel, presented with MI (current age 17.4 +/- 7.9 years) between 1975 and 2006. They were compared with 38 patients with CF (current age 19.3 +/- 6.5 years) without MI matched by sex and CF transmembrane conductance regulator mutation. RESULTS: A total of 66.2% of patients with MI and 73.6% without MI were followed for a prolonged period (24.9 +/- 2.7 years). Of the patients with MI, 31 were managed operatively, whereas 18 were treated successfully with gastrograffin enema, with similar clinical outcomes. Five patients in the MI group and 3 in the control group died during the study period. Bacterial colonization, z score of body mass index, and pulmonary function tests were similar in patients with and without MI in the long term. In younger patients, many clinical parameters were more prevalent in patients with MI (P = 0.004). However, these differences disappeared after the long-term follow-up (up to 31-years). CONCLUSIONS: Patients with CF presenting with MI had similar pulmonary function and nutritional status, as well as survival rates as did the control patients without MI. The distinct genetic mutation found in our population may explain in part the favorable results compared with other studies. In addition, it seems that early diagnosis and treatment of MI in patients with CF may be beneficial, subsequently lowering morbidity, and increasing survival.


Assuntos
Fibrose Cística/complicações , Íleus/complicações , Mecônio , Adolescente , Adulto , Fatores Etários , Índice de Massa Corporal , Criança , Fibrose Cística/mortalidade , Fibrose Cística/terapia , Diatrizoato de Meglumina/uso terapêutico , Progressão da Doença , Enema , Feminino , Humanos , Íleus/terapia , Lactente , Israel , Pulmão , Masculino , Testes de Função Respiratória , Estudos Retrospectivos , Fatores de Risco , Análise de Sobrevida , Resultado do Tratamento , Adulto Jovem
13.
Isr Med Assoc J ; 12(6): 342-7, 2010 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-20928987

RESUMO

BACKGROUND: The rates of anemia in children in southern Israel are high despite the current prevention strategy. A daily dose of "Sprinkles" (SuppleForte, Heinz, Canada), a micronutrient home supplementation, was proven effective for the treatment of anemia worldwide. OBJECTIVES: To assess the efficacy of Sprinkles, a novel supplementation formulation, in the primary prevention of anemia in infants who have free access to health care services. METHODS: A two-arm open-labeled cluster randomized controlled clinical trial was performed in 6 month old Bedouin and Jewish infants. The Sprinkles arm received sachets with iron, vitamins A and C, folic acid and zinc, and the control arm received standard treatment (liquid iron and vitamins A and D). The infants were from families attending Mother and Child Health clinics during 2005-2007. Intervention and follow-up were conducted for babies aged 6-12 months. Health outcomes (hematologic and nutritional indicators, growth parameters, morbidity rates) were evaluated at 12 and 18 months. RESULTS: The final study population numbered 621 infants (328 Bedouin and 293 Jewish); of the parents approached 88.5% agreed to participate. Hemoglobin > 11 g/dl was found in 55% of Bedouin and 40% of Jewish infants (P < 0.01). Bedouin infants had significantly lower serum concentration of iron, folic acid and zinc. All background, hematologic and micronutrient indicators were similar in the two study arms except for a slightly but not clinically significant difference in hemoglobin and hematocrit levels in Bedouins. CONCLUSIONS: Our findings indicate the need to improve the micronutrient status of infants living in the Negev. A cluster randomized trial in MCH clinics is a feasible option.


Assuntos
Micronutrientes/administração & dosagem , Estado Nutricional , Anemia Ferropriva/etnologia , Árabes/estatística & dados numéricos , Suplementos Nutricionais , Feminino , Hematócrito , Humanos , Lactente , Israel/epidemiologia , Judeus/estatística & dados numéricos , Masculino , Estado Nutricional/etnologia
14.
Br J Nutr ; 102(10): 1513-22, 2009 Nov.
Artigo em Inglês | MEDLINE | ID: mdl-19580699

RESUMO

The traditionally semi-nomadic Bedouin Arabs in Israel are undergoing urbanisation with concurrent lifestyle changes, including a shift to using unfortified white-flour bread instead of wholewheat bread as the main dietary staple. We explored associations between the transition from wholewheat to white-flour bread and (1) lifestyle factors, (2) overall diet quality, and (3) health status. We conducted a nutrition survey among 451 Bedouin adults, using a modified 24 h recall questionnaire. Bread intake accounted for 32.7 % of the total energy intake. Those consuming predominantly white bread (PWB) (n 327) were more likely to be urban (OR 2.79; 95 % CI 1.70, 4.58), eating store-bought rather than homemade bread (OR 8.18; 95 % CI 4.34, 15.41) and currently dieting (OR 4.67; 95 % CI 1.28, 17.11) than those consuming predominantly wholewheat bread (PWWB) (n 124). PWB consumption was associated with a lower intake of dietary fibre (23.3 (se 0.6) v. 41.8 (se 1.0) g/d; P < or = 0.001), a higher intake of saturated fats (26.9 v. 24.6 % of total fat; P = 0.013) and lower intakes of Fe (11.0 (se 0.3) v. 16.7 (se 0.4) mg/d), Mg (262.2 (se 5.9) v. 490.3 (se 9.8) mg/d), vitamin E (6.5 (se 0.2) v. 8.6 (se 0.3) mg/d) and most B vitamins than PWWB consumption (P < 0.001 for all), after adjusting for total energy intake. Among those aged > or = 40 years, PWB consumption was associated with a 9.85-fold risk (95 % CI 2.64, 36.71; P = 0.001) of having one or more chronic conditions, as compared with PWWB consumption, after controlling for other risk factors. White bread intake was associated with a less traditional lifestyle and poorer diet quality, and may constitute a useful marker for at-risk subgroups to target for nutritional interventions.


Assuntos
Árabes , Pão , Dieta , Comportamento Alimentar , Estilo de Vida , Adulto , Feminino , Humanos , Masculino , Inquéritos Nutricionais , Estado Nutricional , População Rural , Inquéritos e Questionários , População Urbana
15.
Public Health Nutr ; 12(12): 2464-72, 2009 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-19405990

RESUMO

OBJECTIVE: The purposes of the present study were to estimate individual intake from common-plate meals among Bedouin Arabs using a modified 24 h recall questionnaire, and to evaluate reported energy intake (EI) by comparison with estimated energy requirement (EER). DESIGN: Weighed records were used to develop a method of quantifying intake from common plates. Reported EI and nutrient intakes were obtained from administration of the modified 24 h recall. The relative standard error (RSE) was used to evaluate the reliability of reported nutrient intakes. The FAO/WHO/United Nations University and Oxford equations and reported physical activity levels were used to compute ratios of reported EI to BMR and EER. SETTING: Population centres of traditionally semi-nomadic Bedouin Arabs undergoing sedentarization/urbanization in southern Israel. SUBJECTS: A convenience sample of 451 adults (aged 19-82 years). RESULTS: Mean (se) energy intake was 9648 (276) kJ/d (2306 (66) kcal/d) for men and 8230 (172) kJ/d (1967 (41) kcal/d) for women, of which carbohydrates accounted for 63-64 %. The nutrient intakes evaluated had RSE ratios of less than 25 %. EI:EER ratios ranged from 0.86 to 0.89, and from 0.87 to 0.93 among non-dieters who ate the usual amount on the recall day. CONCLUSIONS: The modified 24 h recall produced plausible estimates of energy and nutrient intakes, comparable to those obtained with the 24 h recall in other populations. The modified questionnaire makes an important contribution to facilitating large-scale nutritional surveillance in the Bedouin population, and may serve as a model for modifying dietary instruments to quantify individual intake in other populations that practise common-plate eating.


Assuntos
Árabes/estatística & dados numéricos , Dieta , Ingestão de Energia/fisiologia , Avaliação Nutricional , Necessidades Nutricionais , Adulto , Idoso , Idoso de 80 Anos ou mais , Registros de Dieta , Inquéritos sobre Dietas , Feminino , Humanos , Israel , Masculino , Rememoração Mental , Pessoa de Meia-Idade , Inquéritos e Questionários , Urbanização , Adulto Jovem
16.
Ethn Dis ; 18(1): 13-8, 2008.
Artigo em Inglês | MEDLINE | ID: mdl-18447093

RESUMO

OBJECTIVE: The goal of this study was to compare eating patterns of Jews and Muslim Bedouins and investigate possible dietary causes for discrepancy in obesity rates. METHODS: We pooled two surveys that included data from 793 Jews and 169 Bedouins aged 35-64years recruited from 1998 through 2003 in southern Israel. For the Jewish sample, we used a proportional geographic cluster random sample of persons aged > or = 35 years. For the Bedouins, a convenience sample of 519 participants was used. Participants were interviewed at home, using modified 24-hour food questionnaires with additional questions regarding health and eating habits. RESULTS: The Jewish group was older and better educated than were the Bedouins. The Bedouins had a higher age-adjusted body mass index than did the Jews (P = .03), and the rate of obesity was higher among Bedouins than Jews (27.9% vs 20.0%, respectively). Compared to Jewish men, Bedouin men reported lower intake of fat, cholesterol, total saturated fat, and protein and fat as a percentage of total energy, but they reported higher intake of carbohydrates, fiber, and carbohydrates as a percentage of total energy. Bedouin women reported lower intake of total saturated fat, percentage of protein and fat, and higher intake of carbohydrates and fiber than did Jewish women. CONCLUSION: The Bedouin population is adapting Western eating patterns that appear to be associated with increased obesity. To address this problem, culturally sensitive intervention programs will have to be developed.


Assuntos
Árabes , Ingestão de Alimentos/etnologia , Judeus , Obesidade/epidemiologia , Adulto , Dieta/etnologia , Feminino , Inquéritos Epidemiológicos , Humanos , Israel/epidemiologia , Masculino , Pessoa de Meia-Idade , Obesidade/etnologia
17.
Nutr J ; 6: 37, 2007 Nov 02.
Artigo em Inglês | MEDLINE | ID: mdl-17980023

RESUMO

BACKGROUND: Undernutrition among older people is a continuing source of concern, particularly among acutely hospitalized patients. The purpose of the current study is to compare malnourished elderly patients with those at nutritional risk and identify factors contributing to the variability between the groups. METHODS: The study was carried out at the Soroka University Medical Center in the south of Israel. From September 2003 through December 2004, all patients 65 years-of-age or older admitted to any of the internal medicine departments, were screened within 72 hours of admission to determine nutritional status using the short version of the Mini Nutritional Assessment (MNA-SF). Patients at nutritional risk were entered the study and were divided into malnourished or 'at risk' based on the full version of the MNA. Data regarding medical, nutritional, functional, and emotional status were obtained by trained interviewers. RESULTS: Two hundred fifty-nine elderly patients, 43.6% men, participated in the study; 18.5% were identified as malnourished and 81.5% were at risk for malnutrition according to the MNA. The malnourished group was less educated, had a higher depression score and lower cognitive and physical functioning. Higher prevalence of chewing problems, nausea, and vomiting was detected among malnourished patients. There was no difference between the groups in health status indicators except for subjective health evaluation which was poorer among the malnourished group. Lower dietary score indicating lower intake of vegetables fruits and fluid, poor appetite and difficulties in eating distinguished between malnourished and at-risk populations with the highest sensitivity and specificity as compare with the anthropometric, global, and self-assessment of nutritional status parts of the MNA. In a multivariate analysis, lower cognitive function, education <12 years and chewing problems were all risk factors for malnutrition. CONCLUSION: Our study indicates that low food consumption as well as poor appetite and chewing problems are associated with the development of malnutrition. Given the critical importance of nutritional status in the hospitalized elderly, further intervention trials are required to determine the best intervention strategies to overcome these problems.


Assuntos
Ingestão de Energia/fisiologia , Avaliação Geriátrica , Desnutrição/diagnóstico , Avaliação Nutricional , Estado Nutricional , Idoso , Apetite/fisiologia , Escolaridade , Feminino , Humanos , Masculino , Mastigação/fisiologia , Análise Multivariada , Medição de Risco , Fatores de Risco , Sensibilidade e Especificidade , Índice de Gravidade de Doença
18.
Nutrients ; 8(4): 234, 2016 Apr 21.
Artigo em Inglês | MEDLINE | ID: mdl-27110817

RESUMO

Early social and economic deprivation, associated with poor nutrition and physical inactivity, may lead to adverse health trajectories. A cluster-randomized controlled-trial examining the effect of a school-based comprehensive intervention on nutrition knowledge, eating habits, and behaviors among low socioeconomic status (LSES) school-aged children was performed. LSES school-aged children (4-7 years) and their mothers were recruited from 11 schools, located in one town. The intervention was implemented on three levels: children, mothers, and teachers. The intervention (IArm) included nutrition classes for children, mothers, and teachers and physical activity (PA) classes for children; the control (CArm) received PA only. Interventions were conducted by professional personnel, who were trained during in a two-day session to deliver the specific program in schools. Family data were obtained by parental interviews. Food knowledge observations, packed lunch records, and anthropometric measurements were obtained in school at baseline, six months, and at the end of the school year. Of 258 children enrolled, 220 (87.6%) completed the six-month program. Only children in the IArm improved their nutrition knowledge and eating-habits and increased food variety and fruit and vegetable consumption, quality score of packed lunches (p < 0.001 for all), habitual water drinking increased (p = 0.02), and decreased sweet-drink consumption (p = 0.05). A school-based comprehensive nutrition intervention targeting LSES population improved eating habits, nutritional knowledge, and healthier packed lunches.


Assuntos
Ciências da Nutrição Infantil , Dieta , Educação em Saúde/métodos , Serviços de Saúde Escolar , Instituições Acadêmicas , Criança , Pré-Escolar , Análise por Conglomerados , Comportamento Alimentar , Feminino , Conhecimentos, Atitudes e Prática em Saúde , Humanos , Masculino , Fatores Socioeconômicos
19.
Obes Surg ; 15(1): 88-94, 2005 Jan.
Artigo em Inglês | MEDLINE | ID: mdl-15760505

RESUMO

BACKGROUND: Patients' nutritional habits are seldom taken in account in planning surgery for clinically severe obesity. Our proposed hypothesis is that the patient's nutritional behavior may influence the outcome of bariatric surgery. METHODS: The impact of nutritional behavior on the postoperative weight-loss was evaluated before and after bariatric surgery. A 6-month prospective consecutive case study was carried out on patients undergoing a Silastic ring vertical gastroplasty (SRVG). Patients were interviewed and examined before and at 1, 3 and 6 months after surgery. Demographic and clinical data were collected from the patients' medical charts. Nutritional data collected from a self-filled questionnaire included information on hunger and satiety perception, nutritional behavior (intake, eating habits and maximum consistency of consumed food) and concomitant symptoms. RESULTS: The sample included 69 patients: 56 were women (81%); average age was 32 years (range 18 50). Average preoperative BMI was 43.4 +/- 5.3 kg/m2 (range 35-58). 6 months after surgery, BMI was 30.3 +/- 3.8 kg/m2 (range 21-42). Weight loss forecast models showed a statistically significant role of factors related to: anthropometrical preoperative data, hunger perception, prevalence of oral mucosal sore, and nutritional behavior. CONCLUSION: The short nutrition outcomes after gastric restrictive surgery were looked at, with their impact on weight-loss success. The Eating Status concept should be part of a systematic profiling of morbidly obese patients for preoperative nutritional behavior and postoperative nutritional education, to achieve the best comprehensive treatment in regard to weight loss and quality of life.


Assuntos
Comportamento Alimentar , Gastroplastia/métodos , Obesidade Mórbida/psicologia , Obesidade Mórbida/cirurgia , Adolescente , Adulto , Análise de Variância , Índice de Massa Corporal , Feminino , Gastroplastia/efeitos adversos , Humanos , Masculino , Pessoa de Meia-Idade , Obesidade Mórbida/diagnóstico , Período Pós-Operatório , Valor Preditivo dos Testes , Cuidados Pré-Operatórios , Probabilidade , Prognóstico , Estudos Prospectivos , Medição de Risco , Estudos de Amostragem , Índice de Gravidade de Doença , Resultado do Tratamento , Redução de Peso
20.
Nutrition ; 21(5): 559-66, 2005 May.
Artigo em Inglês | MEDLINE | ID: mdl-15850961

RESUMO

OBJECTIVE: We measured the difference of dietary intake and eating habits across socioeconomic statuses (SESs) in Israel. METHODS: Participants were randomly recruited from three high SES municipalities and three low SES municipalities in the Negev. Participants were interviewed at home with 24-h food questionnaires that included additional questions regarding health and eating habits. Nutrient and energy intakes were compared between groups, as were major contributors to the energy and food groups. RESULTS: One hundred sixteen participants from the high SES group and 206 from the low SES entered the study. Those in the low SES group were older, heavier, less educated, and less physically active. Dietary intake among the participants in the low SES group was significantly lower in protein, monounsaturated fat, and most vitamins and minerals (thiamine, riboflavin, niacin, vitamin C, calcium, magnesium, and iron). Conversely, vitamin E intake was higher in the low SES group. In the low SES group, the main contributors to energy intake were breads, oils, and sugars. Oils, fats, and citrus fruits were consumed more among subjects in the low SES group, whereas dairy products, grains, and legumes were consumed less by subjects in the high SES group. CONCLUSION: In a detailed survey conducted in two distinct populations, we found poorer diet quality in the low SES group. The root causes for such divergence need further study. As smoking declines in the modern world, nutrition will become the key risk factor in many diseases. Further research and educational and legislative initiatives are needed to curtail this risk.


Assuntos
Dieta/normas , Ingestão de Energia , Exercício Físico/fisiologia , Comportamento Alimentar , Classe Social , Adulto , Análise por Conglomerados , Dieta/economia , Inquéritos sobre Dietas , Escolaridade , Feminino , Humanos , Israel , Masculino , Pessoa de Meia-Idade , Minerais/administração & dosagem , Inquéritos e Questionários , Vitaminas/administração & dosagem
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