Detalhe da pesquisa
1.
Drug Repurposing in Chagas Disease: Chloroquine Potentiates Benznidazole Activity against Trypanosoma cruzi In Vitro and In Vivo.
Antimicrob Agents Chemother
; 66(11): e0028422, 2022 11 15.
Artigo
Inglês
| MEDLINE | ID: mdl-36314800
2.
Nano-multilamellar lipid vesicles promote the induction of SARS-CoV-2 immune responses by a protein-based vaccine formulation.
Nanomedicine
; 45: 102595, 2022 09.
Artigo
Inglês
| MEDLINE | ID: mdl-36031045
3.
Non-Toxic Dimeric Peptides Derived from the Bothropstoxin-I Are Potent SARS-CoV-2 and Papain-like Protease Inhibitors.
Molecules
; 26(16)2021 Aug 12.
Artigo
Inglês
| MEDLINE | ID: mdl-34443484
4.
A Multi-Species Phenotypic Screening Assay for Leishmaniasis Drug Discovery Shows That Active Compounds Display a High Degree of Species-Specificity.
Molecules
; 25(11)2020 May 30.
Artigo
Inglês
| MEDLINE | ID: mdl-32486239
5.
Human induced pluripotent stem cells as a tool for disease modeling and drug screening for COVID-19.
Genet Mol Biol
; 44(1 Suppl 1): e20200198, 2020.
Artigo
Inglês
| MEDLINE | ID: mdl-33275129
6.
Synthesis and structure-activity relationship of nitrile-based cruzain inhibitors incorporating a trifluoroethylamine-based P2 amide replacement.
Bioorg Med Chem
; 27(22): 115083, 2019 11 15.
Artigo
Inglês
| MEDLINE | ID: mdl-31561938
7.
A comparative study of warheads for design of cysteine protease inhibitors.
Bioorg Med Chem Lett
; 27(22): 5031-5035, 2017 11 15.
Artigo
Inglês
| MEDLINE | ID: mdl-29054358
8.
Computer-aided discovery of two novel chalcone-like compounds active and selective against Leishmania infantum.
Bioorg Med Chem Lett
; 27(11): 2459-2464, 2017 06 01.
Artigo
Inglês
| MEDLINE | ID: mdl-28434763
9.
Chroman-4-One Derivatives Targeting Pteridine Reductase 1 and Showing Anti-Parasitic Activity.
Molecules
; 22(3)2017 Mar 08.
Artigo
Inglês
| MEDLINE | ID: mdl-28282886
10.
Proteomic-based approach to gain insight into reprogramming of THP-1 cells exposed to Leishmania donovani over an early temporal window.
Infect Immun
; 83(5): 1853-68, 2015 May.
Artigo
Inglês
| MEDLINE | ID: mdl-25690103
11.
Lipophilic analogs of zoledronate and risedronate inhibit Plasmodium geranylgeranyl diphosphate synthase (GGPPS) and exhibit potent antimalarial activity.
Proc Natl Acad Sci U S A
; 109(11): 4058-63, 2012 Mar 13.
Artigo
Inglês
| MEDLINE | ID: mdl-22392982
12.
Micro-Addition of Silver to Copper: One Small Step in Composition, a Change for a Giant Leap in Biocidal Activity.
Materials (Basel)
; 17(4)2024 Feb 16.
Artigo
Inglês
| MEDLINE | ID: mdl-38399167
13.
A potential antiviral against COVID-19 obtained from Byrsonima coccolobifolia leaves extract.
Fitoterapia
; 173: 105820, 2024 Mar.
Artigo
Inglês
| MEDLINE | ID: mdl-38211642
14.
Antiviral Action against SARS-CoV-2 of a Synthetic Peptide Based on a Novel Defensin Present in the Transcriptome of the Fire Salamander (Salamandra salamandra).
Pharmaceutics
; 16(2)2024 Jan 29.
Artigo
Inglês
| MEDLINE | ID: mdl-38399250
15.
Chemosensitization potential of P-glycoprotein inhibitors in malaria parasites.
Exp Parasitol
; 134(2): 235-43, 2013 Jun.
Artigo
Inglês
| MEDLINE | ID: mdl-23541983
16.
Amazonian plant natural products: perspectives for discovery of new antimalarial drug leads.
Molecules
; 18(8): 9219-40, 2013 Aug 02.
Artigo
Inglês
| MEDLINE | ID: mdl-23917112
17.
Quantum dots: a new tool for anti-malarial drug assays.
Malar J
; 10: 118, 2011 May 09.
Artigo
Inglês
| MEDLINE | ID: mdl-21554712
18.
In vitro and in vivo experimental models for drug screening and development for Chagas disease.
Mem Inst Oswaldo Cruz
; 105(2): 233-8, 2010 Mar.
Artigo
Inglês
| MEDLINE | ID: mdl-20428688
19.
Novel structural CYP51 mutation in Trypanosoma cruzi associated with multidrug resistance to CYP51 inhibitors and reduced infectivity.
Int J Parasitol Drugs Drug Resist
; 13: 107-120, 2020 08.
Artigo
Inglês
| MEDLINE | ID: mdl-32688218
20.
Biological Properties of a Novel Multifunctional Host Defense Peptide from the Skin Secretion of the Chaco Tree Frog, Boana raniceps.
Biomolecules
; 10(5)2020 05 20.
Artigo
Inglês
| MEDLINE | ID: mdl-32443921