Detalhe da pesquisa
1.
Molecular Basis for ADP-Ribose Binding to the Mac1 Domain of SARS-CoV-2 nsp3.
Biochemistry
; 59(28): 2608-2615, 2020 07 21.
Artigo
Inglês
| MEDLINE | ID: mdl-32578982
2.
Fluorescent probe displacement assays reveal unique nucleic acid binding properties of human nudix enzymes.
Anal Biochem
; 595: 113622, 2020 04 15.
Artigo
Inglês
| MEDLINE | ID: mdl-32059949
3.
New Techniques to Study Intracellular Receptors in Living Cells: Insights Into RIG-I-Like Receptor Signaling.
Adv Exp Med Biol
; 1111: 219-240, 2019.
Artigo
Inglês
| MEDLINE | ID: mdl-30471070
4.
Role of the Conserved DECH-Box Cysteine in Coupling Hepatitis C Virus Helicase-Catalyzed ATP Hydrolysis to RNA Unwinding.
Biochemistry
; 57(43): 6247-6255, 2018 10 30.
Artigo
Inglês
| MEDLINE | ID: mdl-30281972
5.
Quantitative microspectroscopic imaging reveals viral and cellular RNA helicase interactions in live cells.
J Biol Chem
; 292(27): 11165-11177, 2017 07 07.
Artigo
Inglês
| MEDLINE | ID: mdl-28483922
6.
Shape-based virtual screening, synthesis and evaluation of novel pyrrolone derivatives as antiviral agents against HCV.
Bioorg Med Chem Lett
; 27(4): 936-940, 2017 02 15.
Artigo
Inglês
| MEDLINE | ID: mdl-28089348
7.
A transplant recipient's pandemic perspective.
Transpl Infect Dis
; 23(5): e13738, 2021 10.
Artigo
Inglês
| MEDLINE | ID: mdl-34590768
8.
Primuline derivatives that mimic RNA to stimulate hepatitis C virus NS3 helicase-catalyzed ATP hydrolysis.
J Biol Chem
; 288(27): 19949-57, 2013 Jul 05.
Artigo
Inglês
| MEDLINE | ID: mdl-23703611
9.
Identification and analysis of hepatitis C virus NS3 helicase inhibitors using nucleic acid binding assays.
Nucleic Acids Res
; 40(17): 8607-21, 2012 Sep 01.
Artigo
Inglês
| MEDLINE | ID: mdl-22740655
10.
Aurintricarboxylic acid modulates the affinity of hepatitis C virus NS3 helicase for both nucleic acid and ATP.
Biochemistry
; 52(36): 6151-9, 2013 Sep 10.
Artigo
Inglês
| MEDLINE | ID: mdl-23947785
11.
Ivermectin is a potent inhibitor of flavivirus replication specifically targeting NS3 helicase activity: new prospects for an old drug.
J Antimicrob Chemother
; 67(8): 1884-94, 2012 Aug.
Artigo
Inglês
| MEDLINE | ID: mdl-22535622
12.
Ceestatin, a novel small molecule inhibitor of hepatitis C virus replication, inhibits 3-hydroxy-3-methylglutaryl-coenzyme A synthase.
J Infect Dis
; 204(4): 609-16, 2011 Aug 15.
Artigo
Inglês
| MEDLINE | ID: mdl-21791663
13.
Development of a Novel, Small-Molecule Brain-Penetrant Histone Deacetylase Inhibitor That Enhances Spatial Memory Formation in Mice.
J Med Chem
; 65(4): 3388-3403, 2022 02 24.
Artigo
Inglês
| MEDLINE | ID: mdl-35133171
14.
DNA damage alters DNA polymerase delta to a form that exhibits increased discrimination against modified template bases and mismatched primers.
Nucleic Acids Res
; 37(2): 647-57, 2009 Feb.
Artigo
Inglês
| MEDLINE | ID: mdl-19074196
15.
Mechanism and specificity of a symmetrical benzimidazolephenylcarboxamide helicase inhibitor.
Biochemistry
; 49(9): 1822-32, 2010 Mar 09.
Artigo
Inglês
| MEDLINE | ID: mdl-20108979
16.
The p12 subunit of human polymerase delta modulates the rate and fidelity of DNA synthesis.
Biochemistry
; 49(17): 3545-54, 2010 May 04.
Artigo
Inglês
| MEDLINE | ID: mdl-20334433
17.
PSI-7851, a pronucleotide of beta-D-2'-deoxy-2'-fluoro-2'-C-methyluridine monophosphate, is a potent and pan-genotype inhibitor of hepatitis C virus replication.
Antimicrob Agents Chemother
; 54(8): 3187-96, 2010 Aug.
Artigo
Inglês
| MEDLINE | ID: mdl-20516278
18.
Discovery of Drug-like Ligands for the Mac1 Domain of SARS-CoV-2 Nsp3.
bioRxiv
; 2020 Sep 01.
Artigo
Inglês
| MEDLINE | ID: mdl-32676591
19.
Discovery of Drug-Like Ligands for the Mac1 Domain of SARS-CoV-2 Nsp3.
SLAS Discov
; 25(10): 1162-1170, 2020 12.
Artigo
Inglês
| MEDLINE | ID: mdl-32981460
20.
Analysis of the evolutionary forces in an immunodominant CD8 epitope in hepatitis C virus at a population level.
J Virol
; 82(7): 3438-51, 2008 Apr.
Artigo
Inglês
| MEDLINE | ID: mdl-18216107