Detalhe da pesquisa
1.
FXR inhibition may protect from SARS-CoV-2 infection by reducing ACE2.
Nature
; 615(7950): 134-142, 2023 03.
Artigo
Inglês
| MEDLINE | ID: mdl-36470304
2.
Hepatocyte-specific deletion of adipose triglyceride lipase (adipose triglyceride lipase/patatin-like phospholipase domain containing 2) ameliorates dietary induced steatohepatitis in mice.
Hepatology
; 75(1): 125-139, 2022 01.
Artigo
Inglês
| MEDLINE | ID: mdl-34387896
3.
Loss of bile salt export pump aggravates lipopolysaccharide-induced liver injury in mice due to impaired hepatic endotoxin clearance.
Hepatology
; 75(5): 1095-1109, 2022 05.
Artigo
Inglês
| MEDLINE | ID: mdl-34927748
4.
Bsep/Abcb11 knockout ameliorates Schistosoma mansoni liver pathology by reducing parasite fecundity.
Liver Int
; 43(11): 2469-2478, 2023 11.
Artigo
Inglês
| MEDLINE | ID: mdl-37641872
5.
24-Norursodeoxycholic acid reshapes immunometabolism in CD8+ T cells and alleviates hepatic inflammation.
J Hepatol
; 75(5): 1164-1176, 2021 11.
Artigo
Inglês
| MEDLINE | ID: mdl-34242699
6.
Monoacylglycerol Lipase Inhibition Protects From Liver Injury in Mouse Models of Sclerosing Cholangitis.
Hepatology
; 71(5): 1750-1765, 2020 05.
Artigo
Inglês
| MEDLINE | ID: mdl-31505038
7.
Absence of Adiponutrin (PNPLA3) and Monoacylglycerol Lipase Synergistically Increases Weight Gain and Aggravates Steatohepatitis in Mice.
Int J Mol Sci
; 22(4)2021 Feb 20.
Artigo
Inglês
| MEDLINE | ID: mdl-33672787
8.
Absence of Bsep/Abcb11 attenuates MCD diet-induced hepatic steatosis but aggravates inflammation in mice.
Liver Int
; 40(6): 1366-1377, 2020 06.
Artigo
Inglês
| MEDLINE | ID: mdl-32141703
9.
Lack of monoacylglycerol lipase prevents hepatic steatosis by favoring lipid storage in adipose tissue and intestinal malabsorption.
J Lipid Res
; 60(7): 1284-1292, 2019 07.
Artigo
Inglês
| MEDLINE | ID: mdl-31048404
10.
Na+ -taurocholate cotransporting polypeptide inhibition has hepatoprotective effects in cholestasis in mice.
Hepatology
; 68(3): 1057-1069, 2018 09.
Artigo
Inglês
| MEDLINE | ID: mdl-29572910
11.
Metabolic preconditioning protects BSEP/ABCB11-/- mice against cholestatic liver injury.
J Hepatol
; 66(1): 95-101, 2017 01.
Artigo
Inglês
| MEDLINE | ID: mdl-27593105
12.
Nuclear Receptor Modulation for the Treatment of Nonalcoholic Fatty Liver Disease.
Semin Liver Dis
; 36(1): 69-86, 2016 Feb.
Artigo
Inglês
| MEDLINE | ID: mdl-26870934
13.
Inhibition of intestinal bile acid absorption improves cholestatic liver and bile duct injury in a mouse model of sclerosing cholangitis.
J Hepatol
; 64(3): 674-81, 2016 Mar.
Artigo
Inglês
| MEDLINE | ID: mdl-26529078
14.
Bile acids in regulation of inflammation and immunity: friend or foe?
Clin Exp Rheumatol
; 34(4 Suppl 98): 25-31, 2016.
Artigo
Inglês
| MEDLINE | ID: mdl-27586800
15.
24-nor-ursodeoxycholic acid ameliorates inflammatory response and liver fibrosis in a murine model of hepatic schistosomiasis.
J Hepatol
; 62(4): 871-8, 2015 Apr.
Artigo
Inglês
| MEDLINE | ID: mdl-25463533
16.
Absence of adipose triglyceride lipase protects from hepatic endoplasmic reticulum stress in mice.
Hepatology
; 56(1): 270-80, 2012 Jul.
Artigo
Inglês
| MEDLINE | ID: mdl-22271167
17.
Non-steroidal FXR agonist cilofexor improves cholestatic liver injury in the Mdr2-/- mouse model of sclerosing cholangitis.
JHEP Rep
; 5(11): 100874, 2023 Nov.
Artigo
Inglês
| MEDLINE | ID: mdl-37841639
18.
GLP-2 Improves Hepatic Inflammation and Fibrosis in Mdr2-/- Mice Via Activation of NR4a1/Nur77 in Hepatic Stellate Cells and Intestinal FXR Signaling.
Cell Mol Gastroenterol Hepatol
; 16(5): 847-856, 2023.
Artigo
Inglês
| MEDLINE | ID: mdl-37572734
19.
Liver Capsule: FXR agonists against liver disease.
Hepatology
; 64(5): 1773, 2016 11.
Artigo
Inglês
| MEDLINE | ID: mdl-27635933
20.
Role of bile acids and their receptors in gastrointestinal and hepatic pathophysiology.
Nat Rev Gastroenterol Hepatol
; 19(7): 432-450, 2022 07.
Artigo
Inglês
| MEDLINE | ID: mdl-35165436