Detalhe da pesquisa
1.
Regenerative cell therapy for the treatment of hyperbilirubinemic Gunn rats with fresh and frozen human induced pluripotent stem cells-derived hepatic stem cells.
Xenotransplantation
; 27(1): e12544, 2020 01.
Artigo
Inglês
| MEDLINE | ID: mdl-31342573
2.
Human hepatocytes derived from pluripotent stem cells: a promising cell model for drug hepatotoxicity screening.
Arch Toxicol
; 90(9): 2049-2061, 2016 Sep.
Artigo
Inglês
| MEDLINE | ID: mdl-27325232
3.
Human neonatal hepatocyte transplantation induces long-term rescue of unconjugated hyperbilirubinemia in the Gunn rat.
Liver Transpl
; 21(6): 801-11, 2015 Jun.
Artigo
Inglês
| MEDLINE | ID: mdl-25821167
4.
In vitro/in vivo screening of oxidative homeostasis and damage to DNA, protein, and lipids using UPLC/MS-MS.
Anal Bioanal Chem
; 406(22): 5465-76, 2014 Sep.
Artigo
Inglês
| MEDLINE | ID: mdl-24969468
5.
miR-133a regulates vitamin K 2,3-epoxide reductase complex subunit 1 (VKORC1), a key protein in the vitamin K cycle.
Mol Med
; 18: 1466-72, 2013 Jan 22.
Artigo
Inglês
| MEDLINE | ID: mdl-23154637
6.
Recent advances in 2D and 3D in vitro systems using primary hepatocytes, alternative hepatocyte sources and non-parenchymal liver cells and their use in investigating mechanisms of hepatotoxicity, cell signaling and ADME.
Arch Toxicol
; 87(8): 1315-530, 2013 Aug.
Artigo
Inglês
| MEDLINE | ID: mdl-23974980
7.
Liver cell culture techniques.
Methods Mol Biol
; 481: 35-46, 2009.
Artigo
Inglês
| MEDLINE | ID: mdl-19096795
8.
Low-density lipoprotein receptor-deficient hepatocytes differentiated from induced pluripotent stem cells allow familial hypercholesterolemia modeling, CRISPR/Cas-mediated genetic correction, and productive hepatitis C virus infection.
Stem Cell Res Ther
; 10(1): 221, 2019 07 29.
Artigo
Inglês
| MEDLINE | ID: mdl-31358055
9.
Identification of apoptotic drugs: multiparametric evaluation in cultured hepatocytes.
Curr Med Chem
; 15(20): 2071-85, 2008.
Artigo
Inglês
| MEDLINE | ID: mdl-18691057
10.
Evaluation of drug-metabolizing and functional competence of human hepatocytes incubated under hypothermia in different media for clinical infusion.
Cell Transplant
; 17(8): 887-97, 2008.
Artigo
Inglês
| MEDLINE | ID: mdl-19069632
11.
Functional assessment of the quality of human hepatocyte preparations for cell transplantation.
Cell Transplant
; 17(10-11): 1211-9, 2008.
Artigo
Inglês
| MEDLINE | ID: mdl-19181215
12.
An update on metabolism studies using human hepatocytes in primary culture.
Expert Opin Drug Metab Toxicol
; 4(7): 837-54, 2008 Jul.
Artigo
Inglês
| MEDLINE | ID: mdl-18624674
13.
[Adipose tissue-derived stem cells: hepatic plasticity]. / Células madre del tejido adiposo: plasticidad hepática.
Gastroenterol Hepatol
; 31(5): 299-309, 2008 May.
Artigo
Espanhol
| MEDLINE | ID: mdl-18448061
14.
Overexpression of SND p102, a rat homologue of p100 coactivator, promotes the secretion of lipoprotein phospholipids in primary hepatocytes.
Biochim Biophys Acta
; 1761(7): 698-708, 2006 Jul.
Artigo
Inglês
| MEDLINE | ID: mdl-16798076
15.
Hepatocytes--the choice to investigate drug metabolism and toxicity in man: in vitro variability as a reflection of in vivo.
Chem Biol Interact
; 168(1): 30-50, 2007 May 20.
Artigo
Inglês
| MEDLINE | ID: mdl-17134688
16.
A human hepatocellular in vitro model to investigate steatosis.
Chem Biol Interact
; 165(2): 106-16, 2007 Jan 30.
Artigo
Inglês
| MEDLINE | ID: mdl-17188672
17.
Using high-content screening technology for studying drug-induced hepatotoxicity in preclinical studies.
Expert Opin Drug Discov
; 12(2): 201-211, 2017 Feb.
Artigo
Inglês
| MEDLINE | ID: mdl-27936962
18.
Alternative Cell Sources to Adult Hepatocytes for Hepatic Cell Therapy.
Methods Mol Biol
; 1506: 17-42, 2017.
Artigo
Inglês
| MEDLINE | ID: mdl-27830543
19.
Hepatogenic differentiation of human mesenchymal stem cells from adipose tissue in comparison with bone marrow mesenchymal stem cells.
World J Gastroenterol
; 12(36): 5834-45, 2006 Sep 28.
Artigo
Inglês
| MEDLINE | ID: mdl-17007050
20.
Hepatocyte cell lines: their use, scope and limitations in drug metabolism studies.
Expert Opin Drug Metab Toxicol
; 2(2): 183-212, 2006 Apr.
Artigo
Inglês
| MEDLINE | ID: mdl-16866607