Detalhe da pesquisa
1.
Cleavage efficiency of the intramembrane protease γ-secretase is reduced by the palmitoylation of a substrate's transmembrane domain.
FASEB J
; 38(2): e23442, 2024 02.
Artigo
Inglês
| MEDLINE | ID: mdl-38275103
2.
An optimized quantitative proteomics method establishes the cell type-resolved mouse brain secretome.
EMBO J
; 39(20): e105693, 2020 10 15.
Artigo
Inglês
| MEDLINE | ID: mdl-32954517
3.
Seizure protein 6 controls glycosylation and trafficking of kainate receptor subunits GluK2 and GluK3.
EMBO J
; 39(15): e103457, 2020 08 03.
Artigo
Inglês
| MEDLINE | ID: mdl-32567721
4.
Roles of developmentally regulated KIF2A alternative isoforms in cortical neuron migration and differentiation.
Development
; 148(4)2021 02 22.
Artigo
Inglês
| MEDLINE | ID: mdl-33531432
5.
The substrate repertoire of γ-secretase/presenilin.
Semin Cell Dev Biol
; 105: 27-42, 2020 09.
Artigo
Inglês
| MEDLINE | ID: mdl-32616437
6.
Genome-wide target analysis of NEUROD2 provides new insights into regulation of cortical projection neuron migration and differentiation.
BMC Genomics
; 16: 681, 2015 Sep 05.
Artigo
Inglês
| MEDLINE | ID: mdl-26341353
7.
Cooperation of N- and C-terminal substrate transmembrane domain segments in intramembrane proteolysis by γ-secretase.
Commun Biol
; 6(1): 177, 2023 02 15.
Artigo
Inglês
| MEDLINE | ID: mdl-36792683
8.
Proteolytically generated soluble Tweak Receptor Fn14 is a blood biomarker for γ-secretase activity.
EMBO Mol Med
; 14(10): e16084, 2022 10 10.
Artigo
Inglês
| MEDLINE | ID: mdl-36069059
9.
The Uppsala APP deletion causes early onset autosomal dominant Alzheimer's disease by altering APP processing and increasing amyloid ß fibril formation.
Sci Transl Med
; 13(606)2021 08 11.
Artigo
Inglês
| MEDLINE | ID: mdl-34380771
10.
NEUROD2 Regulates Stim1 Expression and Store-Operated Calcium Entry in Cortical Neurons.
eNeuro
; 4(1)2017.
Artigo
Inglês
| MEDLINE | ID: mdl-28303257
11.
Pathology-linked protease caught in action.
Science
; 363(6428): 690-691, 2019 02 15.
Artigo
Inglês
| MEDLINE | ID: mdl-30765551