Detalhe da pesquisa
1.
Modular, stereocontrolled Cß-H/Cα-C activation of alkyl carboxylic acids.
Proc Natl Acad Sci U S A
; 116(18): 8721-8727, 2019 04 30.
Artigo
Inglês
| MEDLINE | ID: mdl-30996125
2.
Antimalarial Peptide and Polyketide Natural Products from the Fijian Marine Cyanobacterium Moorea producens.
Mar Drugs
; 18(3)2020 03 18.
Artigo
Inglês
| MEDLINE | ID: mdl-32197482
3.
Peyssonnosides A-B, Unusual Diterpene Glycosides with a Sterically Encumbered Cyclopropane Motif: Structure Elucidation Using an Integrated Spectroscopic and Computational Workflow.
J Org Chem
; 84(13): 8531-8541, 2019 07 05.
Artigo
Inglês
| MEDLINE | ID: mdl-31244158
4.
Antibacterial Oligomeric Polyphenols from the Green Alga Cladophora socialis.
J Org Chem
; 84(9): 5035-5045, 2019 05 03.
Artigo
Inglês
| MEDLINE | ID: mdl-30908914
5.
Targeting Plasmodium PI(4)K to eliminate malaria.
Nature
; 504(7479): 248-253, 2013 Dec 12.
Artigo
Inglês
| MEDLINE | ID: mdl-24284631
6.
KAI407, a potent non-8-aminoquinoline compound that kills Plasmodium cynomolgi early dormant liver stage parasites in vitro.
Antimicrob Agents Chemother
; 58(3): 1586-95, 2014.
Artigo
Inglês
| MEDLINE | ID: mdl-24366744
7.
KAF156 is an antimalarial clinical candidate with potential for use in prophylaxis, treatment, and prevention of disease transmission.
Antimicrob Agents Chemother
; 58(9): 5060-7, 2014 Sep.
Artigo
Inglês
| MEDLINE | ID: mdl-24913172
8.
Probing the Open Global Health Chemical Diversity Library for Multistage-Active Starting Points for Next-Generation Antimalarials.
ACS Infect Dis
; 6(4): 613-628, 2020 04 10.
Artigo
Inglês
| MEDLINE | ID: mdl-32078764
9.
Discovery of short-course antiwolbachial quinazolines for elimination of filarial worm infections.
Sci Transl Med
; 11(491)2019 05 08.
Artigo
Inglês
| MEDLINE | ID: mdl-31068442
10.
Open-source discovery of chemical leads for next-generation chemoprotective antimalarials.
Science
; 362(6419)2018 12 07.
Artigo
Inglês
| MEDLINE | ID: mdl-30523084
11.
High-Throughput Luciferase-Based Assay for the Discovery of Therapeutics That Prevent Malaria.
ACS Infect Dis
; 2(4): 281-293, 2016 Apr 08.
Artigo
Inglês
| MEDLINE | ID: mdl-27275010
12.
Mutations in the P-type cation-transporter ATPase 4, PfATP4, mediate resistance to both aminopyrazole and spiroindolone antimalarials.
ACS Chem Biol
; 10(2): 413-20, 2015 Feb 20.
Artigo
Inglês
| MEDLINE | ID: mdl-25322084
13.
Lead optimization of imidazopyrazines: a new class of antimalarial with activity on Plasmodium liver stages.
ACS Med Chem Lett
; 5(8): 947-50, 2014 Aug 14.
Artigo
Inglês
| MEDLINE | ID: mdl-25147620
14.
Indolcarboxamide is a preclinical candidate for treating multidrug-resistant tuberculosis.
Sci Transl Med
; 5(214): 214ra168, 2013 Dec 04.
Artigo
Inglês
| MEDLINE | ID: mdl-24307692
15.
Imidazolopiperazines: lead optimization of the second-generation antimalarial agents.
J Med Chem
; 55(9): 4244-73, 2012 May 10.
Artigo
Inglês
| MEDLINE | ID: mdl-22524250
16.
Identification of inhibitors for putative malaria drug targets among novel antimalarial compounds.
Mol Biochem Parasitol
; 175(1): 21-9, 2011 Jan.
Artigo
Inglês
| MEDLINE | ID: mdl-20813141
17.
Imidazolopiperazines: hit to lead optimization of new antimalarial agents.
J Med Chem
; 54(14): 5116-30, 2011 Jul 28.
Artigo
Inglês
| MEDLINE | ID: mdl-21644570
18.
Imaging of Plasmodium liver stages to drive next-generation antimalarial drug discovery.
Science
; 334(6061): 1372-7, 2011 Dec 09.
Artigo
Inglês
| MEDLINE | ID: mdl-22096101