Detalhe da pesquisa
1.
TMEM16A/ANO1 suppression improves response to antibody-mediated targeted therapy of EGFR and HER2/ERBB2.
Genes Chromosomes Cancer
; 56(6): 460-471, 2017 06.
Artigo
Inglês
| MEDLINE | ID: mdl-28177558
2.
Variomics screen identifies the re-entrant loop of the calcium-activated chloride channel ANO1 that facilitates channel activation.
J Biol Chem
; 290(2): 889-903, 2015 Jan 09.
Artigo
Inglês
| MEDLINE | ID: mdl-25425649
3.
Calcium-activated chloride channel ANO1 promotes breast cancer progression by activating EGFR and CAMK signaling.
Proc Natl Acad Sci U S A
; 110(11): E1026-34, 2013 Mar 12.
Artigo
Inglês
| MEDLINE | ID: mdl-23431153
4.
Quantitative Proteomic Verification of Membrane Proteins as Potential Therapeutic Targets Located in the 11q13 Amplicon in Cancers.
J Proteome Res
; 14(9): 3670-9, 2015 Sep 04.
Artigo
Inglês
| MEDLINE | ID: mdl-26151158
5.
Small molecule-facilitated degradation of ANO1 protein: a new targeting approach for anticancer therapeutics.
J Biol Chem
; 289(16): 11029-11041, 2014 Apr 18.
Artigo
Inglês
| MEDLINE | ID: mdl-24599954
6.
Class III phosphatidylinositol 4-kinase alpha and beta are novel host factor regulators of hepatitis C virus replication.
J Virol
; 83(19): 10058-74, 2009 Oct.
Artigo
Inglês
| MEDLINE | ID: mdl-19605471
7.
Tumor-Associated Fibroblasts Promote HER2-Targeted Therapy Resistance through FGFR2 Activation.
Clin Cancer Res
; 26(6): 1432-1448, 2020 03 15.
Artigo
Inglês
| MEDLINE | ID: mdl-31699826
8.
Down-regulation of class II phosphoinositide 3-kinase alpha expression below a critical threshold induces apoptotic cell death.
Mol Cancer Res
; 6(4): 614-23, 2008 Apr.
Artigo
Inglês
| MEDLINE | ID: mdl-18403640
9.
Discovery of LSZ102, a Potent, Orally Bioavailable Selective Estrogen Receptor Degrader (SERD) for the Treatment of Estrogen Receptor Positive Breast Cancer.
J Med Chem
; 61(7): 2837-2864, 2018 04 12.
Artigo
Inglês
| MEDLINE | ID: mdl-29562737
10.
Optimization procedure for small interfering RNA transfection in a 384-well format.
J Biomol Screen
; 12(4): 546-59, 2007 Jun.
Artigo
Inglês
| MEDLINE | ID: mdl-17435168
11.
Chemogenomics approaches to novel target discovery.
Expert Rev Proteomics
; 4(3): 411-9, 2007 Jun.
Artigo
Inglês
| MEDLINE | ID: mdl-17552925
12.
ANO1/TMEM16A interacts with EGFR and correlates with sensitivity to EGFR-targeting therapy in head and neck cancer.
Oncotarget
; 6(11): 9173-88, 2015 Apr 20.
Artigo
Inglês
| MEDLINE | ID: mdl-25823819
13.
The pseudophosphatase MK-STYX physically and genetically interacts with the mitochondrial phosphatase PTPMT1.
PLoS One
; 9(4): e93896, 2014.
Artigo
Inglês
| MEDLINE | ID: mdl-24709986
14.
High throughput mutagenesis for identification of residues regulating human prostacyclin (hIP) receptor expression and function.
PLoS One
; 9(6): e97973, 2014.
Artigo
Inglês
| MEDLINE | ID: mdl-24886841
15.
To "grow" or "go": TMEM16A expression as a switch between tumor growth and metastasis in SCCHN.
Clin Cancer Res
; 20(17): 4673-88, 2014 Sep 01.
Artigo
Inglês
| MEDLINE | ID: mdl-24919570
16.
FGFR genetic alterations predict for sensitivity to NVP-BGJ398, a selective pan-FGFR inhibitor.
Cancer Discov
; 2(12): 1118-33, 2012 Dec.
Artigo
Inglês
| MEDLINE | ID: mdl-23002168
17.
Protein kinase D3 sensitizes RAF inhibitor RAF265 in melanoma cells by preventing reactivation of MAPK signaling.
Cancer Res
; 71(12): 4280-91, 2011 Jun 15.
Artigo
Inglês
| MEDLINE | ID: mdl-21527556
18.
MK-STYX, a catalytically inactive phosphatase regulating mitochondrially dependent apoptosis.
Mol Cell Biol
; 31(7): 1357-68, 2011 Apr.
Artigo
Inglês
| MEDLINE | ID: mdl-21262771
19.
Multiple cyclophilins involved in different cellular pathways mediate HCV replication.
Virology
; 397(1): 43-55, 2010 Feb 05.
Artigo
Inglês
| MEDLINE | ID: mdl-19932913
20.
Cholesterol biosynthesis modulation regulates dengue viral replication.
Virology
; 389(1-2): 8-19, 2009 Jun 20.
Artigo
Inglês
| MEDLINE | ID: mdl-19419745