Detalhe da pesquisa
1.
Systemic HIV and SIV latency reversal via non-canonical NF-κB signalling in vivo.
Nature
; 578(7793): 160-165, 2020 02.
Artigo
Inglês
| MEDLINE | ID: mdl-31969707
2.
Discovery of a novel and potent class of anti-HIV-1 maturation inhibitors with improved virology profile against gag polymorphisms.
Bioorg Med Chem Lett
; 27(12): 2689-2694, 2017 06 15.
Artigo
Inglês
| MEDLINE | ID: mdl-28454672
3.
IL-21 and IFNα therapy rescues terminally differentiated NK cells and limits SIV reservoir in ART-treated macaques.
Nat Commun
; 12(1): 2866, 2021 05 17.
Artigo
Inglês
| MEDLINE | ID: mdl-34001890
4.
CTLA-4 and PD-1 dual blockade induces SIV reactivation without control of rebound after antiretroviral therapy interruption.
Nat Med
; 26(4): 519-528, 2020 04.
Artigo
Inglês
| MEDLINE | ID: mdl-32284611
5.
The relative activity of "function sparing" HIV-1 entry inhibitors on viral entry and CCR5 internalization: is allosteric functional selectivity a valuable therapeutic property?
Mol Pharmacol
; 75(3): 490-501, 2009 Mar.
Artigo
Inglês
| MEDLINE | ID: mdl-19064629
6.
Orphan nuclear receptor LRH-1 is required to maintain Oct4 expression at the epiblast stage of embryonic development.
Mol Cell Biol
; 25(9): 3492-505, 2005 May.
Artigo
Inglês
| MEDLINE | ID: mdl-15831456
7.
Identification of liver receptor homolog-1 as a novel regulator of apolipoprotein AI gene transcription.
Mol Endocrinol
; 18(10): 2378-87, 2004 Oct.
Artigo
Inglês
| MEDLINE | ID: mdl-15218078
8.
Identification of a nonsteroidal liver X receptor agonist through parallel array synthesis of tertiary amines.
J Med Chem
; 45(10): 1963-6, 2002 May 09.
Artigo
Inglês
| MEDLINE | ID: mdl-11985463
9.
Synthesis and Biological Evaluation of Macrocyclized Betulin Derivatives as a Novel Class of Anti-HIV-1 Maturation Inhibitors.
Open Med Chem J
; 8: 23-7, 2014.
Artigo
Inglês
| MEDLINE | ID: mdl-25250097
10.
Discovery of tertiary sulfonamides as potent liver X receptor antagonists.
J Med Chem
; 53(8): 3412-6, 2010 Apr 22.
Artigo
Inglês
| MEDLINE | ID: mdl-20345102
11.
Structure-guided design of N-phenyl tertiary amines as transrepression-selective liver X receptor modulators with anti-inflammatory activity.
J Med Chem
; 51(18): 5758-65, 2008 Sep 25.
Artigo
Inglês
| MEDLINE | ID: mdl-18800767
12.
Liver X receptors are regulators of adipocyte gene expression but not differentiation: identification of apoD as a direct target.
J Lipid Res
; 45(4): 616-25, 2004 Apr.
Artigo
Inglês
| MEDLINE | ID: mdl-14703507
13.
Subtype specific effects of peroxisome proliferator-activated receptor ligands on corepressor affinity.
Biochemistry
; 42(31): 9278-87, 2003 Aug 12.
Artigo
Inglês
| MEDLINE | ID: mdl-12899614
14.
Structural basis for antagonist-mediated recruitment of nuclear co-repressors by PPARalpha.
Nature
; 415(6873): 813-7, 2002 Feb 14.
Artigo
Inglês
| MEDLINE | ID: mdl-11845213