Detalhe da pesquisa
1.
Droplet Tn-Seq identifies the primary secretion mechanism for yersiniabactin in Yersinia pestis.
EMBO Rep
; 24(10): e57369, 2023 10 09.
Artigo
Inglês
| MEDLINE | ID: mdl-37501563
2.
Structural insights into the diverse prenylating capabilities of DMATS prenyltransferases.
Nat Prod Rep
; 41(1): 113-147, 2024 Jan 24.
Artigo
Inglês
| MEDLINE | ID: mdl-37929638
3.
Targeting thiol isomerase activity with zafirlukast to treat ovarian cancer from the bench to clinic.
FASEB J
; 37(5): e22914, 2023 05.
Artigo
Inglês
| MEDLINE | ID: mdl-37043381
4.
A consensus reverse docking approach for identification of a competitive inhibitor of acetyltransferase enhanced intracellular survival protein from Mycobacterium tuberculosis.
Bioorg Med Chem
; 108: 117774, 2024 Jun 15.
Artigo
Inglês
| MEDLINE | ID: mdl-38833750
5.
Yersiniabactin contributes to overcoming zinc restriction during Yersinia pestis infection of mammalian and insect hosts.
Proc Natl Acad Sci U S A
; 118(44)2021 11 02.
Artigo
Inglês
| MEDLINE | ID: mdl-34716262
6.
Inhibition of Fosfomycin Resistance Protein FosB from Gram-Positive Pathogens by Phosphonoformate.
Biochemistry
; 62(1): 109-117, 2023 01 03.
Artigo
Inglês
| MEDLINE | ID: mdl-36525630
7.
Discovery and Mechanistic Analysis of Structurally Diverse Inhibitors of Acetyltransferase Eis among FDA-Approved Drugs.
Biochemistry
; 62(3): 710-721, 2023 02 07.
Artigo
Inglês
| MEDLINE | ID: mdl-36657084
8.
A comprehensive overview of the medicinal chemistry of antifungal drugs: perspectives and promise.
Chem Soc Rev
; 49(8): 2426-2480, 2020 Apr 21.
Artigo
Inglês
| MEDLINE | ID: mdl-32140691
9.
Structural basis for backbone N-methylation by an interrupted adenylation domain.
Nat Chem Biol
; 14(5): 428-430, 2018 05.
Artigo
Inglês
| MEDLINE | ID: mdl-29556104
10.
Synergistic combinations of azoles and antihistamines against Candida species in vitro.
Med Mycol
; 57(7): 874-884, 2019 Oct 01.
Artigo
Inglês
| MEDLINE | ID: mdl-30295881
11.
Investigating the promiscuity of the chloramphenicol nitroreductase from Haemophilus influenzae towards the reduction of 4-nitrobenzene derivatives.
Bioorg Med Chem Lett
; 29(9): 1127-1132, 2019 05 01.
Artigo
Inglês
| MEDLINE | ID: mdl-30826292
12.
Probing the limits of interrupted adenylation domains by engineering a trifunctional enzyme capable of adenylation, N-, and S-methylation.
Org Biomol Chem
; 17(5): 1169-1175, 2019 01 31.
Artigo
Inglês
| MEDLINE | ID: mdl-30644493
13.
Comprehensive review of chemical strategies for the preparation of new aminoglycosides and their biological activities.
Chem Soc Rev
; 47(4): 1189-1249, 2018 Feb 19.
Artigo
Inglês
| MEDLINE | ID: mdl-29296992
14.
Combining Chalcones with Donepezil to Inhibit Both Cholinesterases and Aß Fibril Assembly.
Molecules
; 25(1)2019 Dec 24.
Artigo
Inglês
| MEDLINE | ID: mdl-31878304
15.
Acetylation by Eis and Deacetylation by Rv1151c of Mycobacterium tuberculosis HupB: Biochemical and Structural Insight.
Biochemistry
; 57(5): 781-790, 2018 02 06.
Artigo
Inglês
| MEDLINE | ID: mdl-29345920
16.
Using MbtH-Like Proteins to Alter the Substrate Profile of a Nonribosomal Peptide Adenylation Enzyme.
Chembiochem
; 19(20): 2186-2194, 2018 10 18.
Artigo
Inglês
| MEDLINE | ID: mdl-30134012
17.
Novel fluconazole derivatives with promising antifungal activity.
Bioorg Med Chem
; 26(3): 573-580, 2018 02 01.
Artigo
Inglês
| MEDLINE | ID: mdl-29279242
18.
Multifunctional Donepezil Analogues as Cholinesterase and BACE1 Inhibitors.
Molecules
; 23(12)2018 Dec 08.
Artigo
Inglês
| MEDLINE | ID: mdl-30544832
19.
Differential Effects of Linkers on the Activity of Amphiphilic Tobramycin Antifungals.
Molecules
; 23(4)2018 Apr 13.
Artigo
Inglês
| MEDLINE | ID: mdl-29652845
20.
Deciphering Nature's Intricate Way of N,S-Dimethylating l-Cysteine: Sequential Action of Two Bifunctional Adenylation Domains.
Biochemistry
; 56(46): 6087-6097, 2017 11 21.
Artigo
Inglês
| MEDLINE | ID: mdl-29112395