Detalhe da pesquisa
1.
Long-term dietary nitrate supplementation slows the progression of established atherosclerosis in ApoE-/- mice fed a high fat diet.
Eur J Nutr
; 62(4): 1845-1857, 2023 Jun.
Artigo
Inglês
| MEDLINE | ID: mdl-36853380
2.
Relaxin Inhibits the Cardiac Myofibroblast NLRP3 Inflammasome as Part of Its Anti-Fibrotic Actions via the Angiotensin Type 2 and ATP (P2X7) Receptors.
Int J Mol Sci
; 23(13)2022 Jun 25.
Artigo
Inglês
| MEDLINE | ID: mdl-35806076
3.
N-(Methyloxycarbonyl)thiophene sulfonamides as high affinity AT2 receptor ligands.
Bioorg Med Chem
; 29: 115859, 2021 01 01.
Artigo
Inglês
| MEDLINE | ID: mdl-33309749
4.
Serelaxin inhibits the profibrotic TGF-ß1/IL-1ß axis by targeting TLR-4 and the NLRP3 inflammasome in cardiac myofibroblasts.
FASEB J
; 33(12): 14717-14733, 2019 12.
Artigo
Inglês
| MEDLINE | ID: mdl-31689135
5.
A Novel Epigenetic Drug-Eluting Balloon Angioplasty Device: Evaluation in a Large Animal Model of Neointimal Hyperplasia.
Cardiovasc Drugs Ther
; 33(6): 687-692, 2019 12.
Artigo
Inglês
| MEDLINE | ID: mdl-31885055
6.
N-(Heteroaryl)thiophene sulfonamides as angiotensin AT2 receptor ligands.
Eur J Med Chem
; 265: 116122, 2024 Feb 05.
Artigo
Inglês
| MEDLINE | ID: mdl-38199164
7.
The single-chain relaxin mimetic, B7-33, maintains the cardioprotective effects of relaxin and more rapidly reduces left ventricular fibrosis compared to perindopril in an experimental model of cardiomyopathy.
Biomed Pharmacother
; 160: 114370, 2023 Apr.
Artigo
Inglês
| MEDLINE | ID: mdl-36753958
8.
Novel AT2R agonist, ß-Pro7Ang III, is cardio- and vaso-protective in diabetic spontaneously hypertensive rats.
Biomed Pharmacother
; 165: 115238, 2023 Sep.
Artigo
Inglês
| MEDLINE | ID: mdl-37536036
9.
Vasoprotective and atheroprotective effects of angiotensin (1-7) in apolipoprotein E-deficient mice.
Arterioscler Thromb Vasc Biol
; 30(8): 1606-13, 2010 Aug.
Artigo
Inglês
| MEDLINE | ID: mdl-20448208
10.
Simultaneous targeting of oxidative stress and fibrosis reverses cardiomyopathy-induced ventricular remodelling and dysfunction.
Br J Pharmacol
; 178(12): 2424-2442, 2021 06.
Artigo
Inglês
| MEDLINE | ID: mdl-33660265
11.
In Aged Females, the Enhanced Pressor Response to Angiotensin II Is Attenuated By Estrogen Replacement via an Angiotensin Type 2 Receptor-Mediated Mechanism.
Hypertension
; 78(1): 128-137, 2021 07.
Artigo
Inglês
| MEDLINE | ID: mdl-33966450
12.
Relaxin Attenuates Organ Fibrosis via an Angiotensin Type 2 Receptor Mechanism in Aged Hypertensive Female Rats.
Kidney360
; 2(11): 1781-1792, 2021 11 25.
Artigo
Inglês
| MEDLINE | ID: mdl-35373008
13.
Effect of tocopheryl phosphate on key biomarkers of inflammation: Implication in the reduction of atherosclerosis progression in a hypercholesterolaemic rabbit model.
Clin Exp Pharmacol Physiol
; 37(5-6): 587-92, 2010 May.
Artigo
Inglês
| MEDLINE | ID: mdl-20082629
14.
Relaxin Can Mediate Its Anti-Fibrotic Effects by Targeting the Myofibroblast NLRP3 Inflammasome at the Level of Caspase-1.
Front Pharmacol
; 11: 1201, 2020.
Artigo
Inglês
| MEDLINE | ID: mdl-32848798
15.
Serelaxin and the AT2 Receptor Agonist CGP42112 Evoked a Similar, Nonadditive, Cardiac Antifibrotic Effect in High Salt-Fed Mice That Were Refractory to Candesartan Cilexetil.
ACS Pharmacol Transl Sci
; 3(1): 76-87, 2020 Feb 14.
Artigo
Inglês
| MEDLINE | ID: mdl-32259090
16.
AT2 receptors: functional relevance in cardiovascular disease.
Pharmacol Ther
; 120(3): 292-316, 2008 Dec.
Artigo
Inglês
| MEDLINE | ID: mdl-18804122
17.
Chronic angiotensin IV treatment reverses endothelial dysfunction in ApoE-deficient mice.
Cardiovasc Res
; 77(1): 178-87, 2008 Jan.
Artigo
Inglês
| MEDLINE | ID: mdl-18006471
18.
A novel histone deacetylase inhibitor reduces abdominal aortic aneurysm formation in angiotensin II-infused apolipoprotein E-deficient mice.
J Vasc Res
; 45(2): 143-52, 2008.
Artigo
Inglês
| MEDLINE | ID: mdl-17957103
19.
Anti-fibrotic Potential of AT2 Receptor Agonists.
Front Pharmacol
; 8: 564, 2017.
Artigo
Inglês
| MEDLINE | ID: mdl-28912715
20.
Differential regulation by AT(1) and AT(2) receptors of angiotensin II-stimulated cyclic GMP production in rat uterine artery and aorta.
Br J Pharmacol
; 141(6): 1024-31, 2004 Mar.
Artigo
Inglês
| MEDLINE | ID: mdl-14993097