1.
Org Biomol Chem
; 13(42): 10569-77, 2015 Nov 14.
Artigo
em Inglês
| MEDLINE
| ID: mdl-26340318
RESUMO
Several 9-(2-aminoethyl)anthracene derivatives were prepared with different nitrogen substitutents including alkyl, acetamide, trifluoroacaeamide and t-butyl carbamate. The selectivity in Diels-Alder cyclodaddition reaction with N-methyl maleimide was evaluated through single crystal X-ray analysis of the products. Models for the change in selectivity with hydrogen bond acceptor are proposed, supported by DFT level calculations.