1.
Eksp Klin Farmakol
; 61(4): 44-7, 1998.
Artigo
em Russo
| MEDLINE
| ID: mdl-9783109
RESUMO
The activity of the natural peptide complex of the kidneys and of its synthetic analogs (PEKDLRK, PEKDSRK, PEKDDRL) in autoimmune nephritis was studied on golden hamsters. All the peptides under study demonstrated therapeutic activity but were characterized by peculiarity of their effect. The peptide PEKDLRK possessed the most marked capacity for stimulating phagocytic reactions, PEKDDRL apparently activated the system of natural killers. It is concluded that the study of peptides-analogs as potential drugs is promising.