Detalhe da pesquisa
1.
4-Hydroxy-2-pyridones: Discovery and evaluation of a novel class of antibacterial agents targeting DNA synthesis.
Bioorg Med Chem Lett
; 27(22): 5014-5021, 2017 11 15.
Artigo
Inglês
| MEDLINE | ID: mdl-29032026
2.
Establishing the concept of aza-[3 + 3] annulations using enones as a key expansion of this unified strategy in alkaloid synthesis.
Beilstein J Org Chem
; 9: 1170-8, 2013.
Artigo
Inglês
| MEDLINE | ID: mdl-23843910
3.
Ribonucleotide reductase, a novel drug target for gonorrhea.
Elife
; 112022 02 09.
Artigo
Inglês
| MEDLINE | ID: mdl-35137690
4.
Potent Antimalarials with Development Potential Identified by Structure-Guided Computational Optimization of a Pyrrole-Based Dihydroorotate Dehydrogenase Inhibitor Series.
J Med Chem
; 64(9): 6085-6136, 2021 05 13.
Artigo
Inglês
| MEDLINE | ID: mdl-33876936
5.
Discovery and Optimization of Indolyl-Containing 4-Hydroxy-2-Pyridone Type II DNA Topoisomerase Inhibitors Active against Multidrug Resistant Gram-negative Bacteria.
J Med Chem
; 61(10): 4456-4475, 2018 05 24.
Artigo
Inglês
| MEDLINE | ID: mdl-29727185
6.
Stereodivergent total syntheses of precoccinelline, hippodamine, coccinelline, and convergine.
Org Lett
; 8(21): 4899-902, 2006 Oct 12.
Artigo
Inglês
| MEDLINE | ID: mdl-17020331
7.
A Novel and Highly Stereoselective Intramolecular Formal [3+3] Cycloaddition Reaction of Vinylogous Amides Tethered with α,ß-Unsaturated Aldehydes: A Formal Total Synthesis of (+)-Gephyrotoxin.
Angew Chem Int Ed Engl
; 40(8): 1516-1518, 2001 Apr 17.
Artigo
Inglês
| MEDLINE | ID: mdl-29712373
8.
Correction to Discovery and Optimization of Indolyl-Containing 4-Hydroxy-2-pyridone Type II DNA Topoisomerase Inhibitors Active against Multidrug Resistant Gram-Negative Bacteria.
J Med Chem
; 61(20): 9394, 2018 Oct 25.
Artigo
Inglês
| MEDLINE | ID: mdl-30351051
9.
Asymmetric aza-[3+3] annulation in the synthesis of indolizidines: an unexpected reversal of regiochemistry.
Org Lett
; 13(16): 4402-5, 2011 Aug 19.
Artigo
Inglês
| MEDLINE | ID: mdl-21786757
10.
A Novel and Highly Stereoselective Intramolecular Formal
Angew Chem Int Ed Engl
; 40(8): 1516-1518, 2001 Apr 17.
Artigo
Inglês
| MEDLINE | ID: mdl-11317320
11.
A General Approach to the Quinolizidine Alkaloids via an Intramolecular Aza-[3 + 3] Annulation. Synthesis of (±)-2-Deoxy-Lasubine II.
Synlett
; 2009(2): 237-240, 2008 Jan 01.
Artigo
Inglês
| MEDLINE | ID: mdl-19617925
12.
An intramolecular aza-[3+3] annulation approach to azaphenalene alkaloids. Total synthesis of myrrhine.
J Org Chem
; 72(7): 2476-84, 2007 Mar 30.
Artigo
Inglês
| MEDLINE | ID: mdl-17338572
13.
A formal [3 + 3] cycloaddition reaction. 5. An enantioselective intramolecular formal aza-[3 + 3] cycloaddition reaction promoted by chiral amine salts.
J Org Chem
; 70(11): 4248-56, 2005 May 27.
Artigo
Inglês
| MEDLINE | ID: mdl-15903297
14.
Total syntheses of enantiomerically enriched R-(+)- and S-(-)-deplancheine.
Org Biomol Chem
; 3(11): 2140-4, 2005 Jun 07.
Artigo
Inglês
| MEDLINE | ID: mdl-15917902
15.
Stereoselective formal [3 + 3] cycloaddition approach to cis-1-azadecalins and synthesis of (-)-4a,8a-diepi-pumiliotoxin C. evidence for the first highly stereoselective 6pi-electron electrocyclic ring closures of 1-azatrienes.
J Am Chem Soc
; 124(35): 10435-42, 2002 Sep 04.
Artigo
Inglês
| MEDLINE | ID: mdl-12197745
16.
A formal [3 + 3] cycloaddition reaction. Improved reactivity using alpha,beta-unsaturated iminium salts and evidence for reversibility of 6pi-electron electrocyclic ring closure of 1-oxatrienes.
J Org Chem
; 68(5): 1729-35, 2003 Mar 07.
Artigo
Inglês
| MEDLINE | ID: mdl-12608785