Detalhe da pesquisa
1.
Parkin Regulates Mitosis and Genomic Stability through Cdc20/Cdh1.
Mol Cell
; 60(1): 21-34, 2015 Oct 01.
Artigo
Inglês
| MEDLINE | ID: mdl-26387737
2.
ER-stress-associated functional link between Parkin and DJ-1 via a transcriptional cascade involving the tumor suppressor p53 and the spliced X-box binding protein XBP-1.
J Cell Sci
; 126(Pt 9): 2124-33, 2013 May 01.
Artigo
Inglês
| MEDLINE | ID: mdl-23447676
3.
Loss of leucine-rich repeat kinase 2 causes impairment of protein degradation pathways, accumulation of alpha-synuclein, and apoptotic cell death in aged mice.
Proc Natl Acad Sci U S A
; 107(21): 9879-84, 2010 May 25.
Artigo
Inglês
| MEDLINE | ID: mdl-20457918
4.
Huntington's disease phenotypes are improved via mTORC1 modulation by small molecule therapy.
PLoS One
; 17(8): e0273710, 2022.
Artigo
Inglês
| MEDLINE | ID: mdl-36037192
5.
p53-dependent control of transactivation of the Pen2 promoter by presenilins.
J Cell Sci
; 122(Pt 21): 4003-8, 2009 Nov 01.
Artigo
Inglês
| MEDLINE | ID: mdl-19889971
6.
Periphilin is a novel interactor of synphilin-1, a protein implicated in Parkinson's disease.
Neurogenetics
; 11(2): 203-15, 2010 May.
Artigo
Inglês
| MEDLINE | ID: mdl-19730898
7.
p53-dependent control of cell death by nicastrin: lack of requirement for presenilin-dependent gamma-secretase complex.
J Neurochem
; 109(1): 225-37, 2009 Apr.
Artigo
Inglês
| MEDLINE | ID: mdl-19187441
8.
Discovery of NV-5138, the first selective Brain mTORC1 activator.
Sci Rep
; 9(1): 4107, 2019 03 11.
Artigo
Inglês
| MEDLINE | ID: mdl-30858438
9.
Age-Dependent Dopaminergic Neurodegeneration and Impairment of the Autophagy-Lysosomal Pathway in LRRK-Deficient Mice.
Neuron
; 96(4): 796-807.e6, 2017 Nov 15.
Artigo
Inglês
| MEDLINE | ID: mdl-29056298
10.
PINK1 triggers autocatalytic activation of Parkin to specify cell fate decisions.
Curr Biol
; 24(16): 1854-65, 2014 Aug 18.
Artigo
Inglês
| MEDLINE | ID: mdl-25088558
11.
Loss of DJ-1 does not affect mitochondrial respiration but increases ROS production and mitochondrial permeability transition pore opening.
PLoS One
; 7(7): e40501, 2012.
Artigo
Inglês
| MEDLINE | ID: mdl-22792356
12.
Loss of leucine-rich repeat kinase 2 causes age-dependent bi-phasic alterations of the autophagy pathway.
Mol Neurodegener
; 7: 2, 2012 Jan 09.
Artigo
Inglês
| MEDLINE | ID: mdl-22230652
13.
Regulation of mitochondrial permeability transition pore by PINK1.
Mol Neurodegener
; 7: 22, 2012 May 25.
Artigo
Inglês
| MEDLINE | ID: mdl-22630785
14.
A chemical genetic approach to probe the function of PINK1 in regulating mitochondrial dynamics.
Cell Res
; 25(3): 394-7, 2015 Mar.
Artigo
Inglês
| MEDLINE | ID: mdl-25475060
15.
Transcriptional repression of p53 by parkin and impairment by mutations associated with autosomal recessive juvenile Parkinson's disease.
Nat Cell Biol
; 11(11): 1370-5, 2009 Nov.
Artigo
Inglês
| MEDLINE | ID: mdl-19801972
16.
Study on the putative contribution of caspases and the proteasome to the degradation of Aph-1a and Pen-2.
Neurodegener Dis
; 4(2-3): 156-63, 2007.
Artigo
Inglês
| MEDLINE | ID: mdl-17596710
17.
Caspase-3-derived C-terminal product of synphilin-1 displays antiapoptotic function via modulation of the p53-dependent cell death pathway.
J Biol Chem
; 281(17): 11515-22, 2006 Apr 28.
Artigo
Inglês
| MEDLINE | ID: mdl-16495229