Detalhe da pesquisa
1.
Circulating Cancer-Associated Macrophage-like Cells as a Blood-Based Biomarker of Response to Immune Checkpoint Inhibitors.
Int J Mol Sci
; 25(7)2024 Mar 28.
Artigo
Inglês
| MEDLINE | ID: mdl-38612563
2.
Targeting GLI1 and GLI2 with small molecule inhibitors to suppress GLI-dependent transcription and tumor growth.
Pharmacol Res
; 195: 106858, 2023 09.
Artigo
Inglês
| MEDLINE | ID: mdl-37473878
3.
A gene dosage-dependent effect unveils NBS1 as both a haploinsufficient tumour suppressor and an essential gene for SHH-medulloblastoma.
Neuropathol Appl Neurobiol
; 48(6): e12837, 2022 10.
Artigo
Inglês
| MEDLINE | ID: mdl-35839783
4.
Structural Characterization of Human Heat Shock Protein 90 N-Terminal Domain and Its Variants K112R and K112A in Complex with a Potent 1,2,3-Triazole-Based Inhibitor.
Int J Mol Sci
; 23(16)2022 Aug 21.
Artigo
Inglês
| MEDLINE | ID: mdl-36012721
5.
New classes of potent heparanase inhibitors from ligand-based virtual screening.
J Enzyme Inhib Med Chem
; 35(1): 1685-1696, 2020 Dec.
Artigo
Inglês
| MEDLINE | ID: mdl-32907434
6.
The Control of Heparanase Through the Use of Small Molecules.
Adv Exp Med Biol
; 1221: 567-603, 2020.
Artigo
Inglês
| MEDLINE | ID: mdl-32274727
7.
Insight into genetic susceptibility to male breast cancer by multigene panel testing: Results from a multicenter study in Italy.
Int J Cancer
; 145(2): 390-400, 2019 07 15.
Artigo
Inglês
| MEDLINE | ID: mdl-30613976
8.
Synthesis and preliminary in vitro evaluation of DOTA-Tenatumomab conjugates for theranostic applications in tenascin expressing tumors.
Bioorg Med Chem
; 27(15): 3248-3253, 2019 08 01.
Artigo
Inglês
| MEDLINE | ID: mdl-31208798
9.
Synthesis of Bromoundecyl Resorc[4]arenes and Applications of the Cone Stereoisomer as Selector for Liquid Chromatography.
J Org Chem
; 83(15): 7683-7693, 2018 08 03.
Artigo
Inglês
| MEDLINE | ID: mdl-29812952
10.
Growth inhibition of human ovarian carcinoma by a novel AvidinOX-anchored biotinylated camptothecin derivative.
Bioorg Med Chem Lett
; 28(20): 3312-3314, 2018 11 01.
Artigo
Inglês
| MEDLINE | ID: mdl-30243588
11.
Characterization of therapeutic protein AvidinOX by an integrated analytical approach.
Anal Bioanal Chem
; 410(2): 553-564, 2018 Jan.
Artigo
Inglês
| MEDLINE | ID: mdl-29167933
12.
Whole-exome sequencing and targeted gene sequencing provide insights into the role of PALB2 as a male breast cancer susceptibility gene.
Cancer
; 123(2): 210-218, 2017 01 01.
Artigo
Inglês
| MEDLINE | ID: mdl-27648926
13.
Arylamidonaphtalene sulfonate compounds as a novel class of heparanase inhibitors.
Bioorg Med Chem Lett
; 27(18): 4421-4425, 2017 09 15.
Artigo
Inglês
| MEDLINE | ID: mdl-28811133
14.
Kinetic analysis and molecular modeling of the inhibition mechanism of roneparstat (SST0001) on human heparanase.
Glycobiology
; 26(6): 640-54, 2016 06.
Artigo
Inglês
| MEDLINE | ID: mdl-26762172
15.
The novel atypical retinoid ST5589 down-regulates Aurora Kinase A and has anti-tumour activity in lymphoma pre-clinical models.
Br J Haematol
; 171(3): 378-86, 2015 Nov.
Artigo
Inglês
| MEDLINE | ID: mdl-26235926
16.
Ruthenium-catalyzed synthesis of 5-amino-1,2,3-triazole-4-carboxylates for triazole-based scaffolds: beyond the dimroth rearrangement.
J Org Chem
; 80(5): 2562-72, 2015 Mar 06.
Artigo
Inglês
| MEDLINE | ID: mdl-25654488
17.
Exploring in vitro and in vivo Hsp90 inhibitors activity against human protozoan parasites.
Bioorg Med Chem Lett
; 25(3): 462-5, 2015 Feb 01.
Artigo
Inglês
| MEDLINE | ID: mdl-25547934
18.
Hydroxamic acid based histone deacetylase inhibitors with confirmed activity against the malaria parasite.
Bioorg Med Chem Lett
; 25(3): 459-61, 2015 Feb 01.
Artigo
Inglês
| MEDLINE | ID: mdl-25563890
19.
Investigation on the ZBG-functionality of phenyl-4-yl-acrylohydroxamic acid derivatives as histone deacetylase inhibitors.
Bioorg Med Chem Lett
; 25(20): 4457-60, 2015 Oct 15.
Artigo
Inglês
| MEDLINE | ID: mdl-26376355
20.
Novel and recurrent BRCA2 mutations in Italian breast/ovarian cancer families widen the ovarian cancer cluster region boundaries to exons 13 and 14.
Breast Cancer Res Treat
; 148(3): 629-35, 2014 Dec.
Artigo
Inglês
| MEDLINE | ID: mdl-25395318