Detalhe da pesquisa
1.
Drug Repurposing in Chagas Disease: Chloroquine Potentiates Benznidazole Activity against Trypanosoma cruzi In Vitro and In Vivo.
Antimicrob Agents Chemother
; 66(11): e0028422, 2022 11 15.
Artigo
Inglês
| MEDLINE | ID: mdl-36314800
2.
Priming astrocytes with TNF enhances their susceptibility to Trypanosoma cruzi infection and creates a self-sustaining inflammatory milieu.
J Neuroinflammation
; 14(1): 182, 2017 Sep 06.
Artigo
Inglês
| MEDLINE | ID: mdl-28877735
3.
The beneficial effect of fluoxetine on behavioral and cognitive changes in chronic experimental Chagas disease unveils the role of serotonin fueling astrocyte infection by Trypanosoma cruzi.
PLoS Negl Trop Dis
; 18(5): e0012199, 2024 May 22.
Artigo
Inglês
| MEDLINE | ID: mdl-38776344
4.
Preclinical evaluation of combined therapy with amiodarone and low-dose benznidazole in a mouse model of chronic Trypanosoma cruzi infection.
Biomed Pharmacother
; 175: 116742, 2024 May 15.
Artigo
Inglês
| MEDLINE | ID: mdl-38754265
5.
Modulation of miR-145-5p and miR-146b-5p levels is linked to reduced parasite load in H9C2 Trypanosoma cruzi infected cardiomyoblasts.
Sci Rep
; 12(1): 1436, 2022 01 26.
Artigo
Inglês
| MEDLINE | ID: mdl-35082354
6.
Sulfadiazine Plus Pyrimethamine Therapy Reversed Multiple Behavioral and Neurocognitive Changes in Long-Term Chronic Toxoplasmosis by Reducing Brain Cyst Load and Inflammation-Related Alterations.
Front Immunol
; 13: 822567, 2022.
Artigo
Inglês
| MEDLINE | ID: mdl-35572567
7.
Physical Exercise Promotes a Reduction in Cardiac Fibrosis in the Chronic Indeterminate Form of Experimental Chagas Disease.
Front Immunol
; 12: 712034, 2021.
Artigo
Inglês
| MEDLINE | ID: mdl-34804007
8.
Behavioral alterations in long-term Toxoplasma gondii infection of C57BL/6 mice are associated with neuroinflammation and disruption of the blood brain barrier.
PLoS One
; 16(10): e0258199, 2021.
Artigo
Inglês
| MEDLINE | ID: mdl-34610039
9.
"Chagas Express XXI": A new ArtScience social technology for health and science education-A case study in Brazilian endemic areas of Chagas disease with an active search of chronic cases.
PLoS Negl Trop Dis
; 15(7): e0009534, 2021 07.
Artigo
Inglês
| MEDLINE | ID: mdl-34288905
10.
CCL3/Macrophage Inflammatory Protein-1α Is Dually Involved in Parasite Persistence and Induction of a TNF- and IFNγ-Enriched Inflammatory Milieu in Trypanosoma cruzi-Induced Chronic Cardiomyopathy.
Front Immunol
; 11: 306, 2020.
Artigo
Inglês
| MEDLINE | ID: mdl-32194558
11.
Genetic Polymorphism at CCL5 Is Associated With Protection in Chagas' Heart Disease: Antagonistic Participation of CCR1+ and CCR5+ Cells in Chronic Chagasic Cardiomyopathy.
Front Immunol
; 9: 615, 2018.
Artigo
Inglês
| MEDLINE | ID: mdl-29696014
12.
Pentoxifylline reverses chronic experimental Chagasic cardiomyopathy in association with repositioning of abnormal CD8+ T-cell response.
PLoS Negl Trop Dis
; 9(3): e0003659, 2015 Mar.
Artigo
Inglês
| MEDLINE | ID: mdl-25789471
13.
Effects of perillyl alcohol in glial C6 cell line in vitro and anti-metastatic activity in chorioallantoic membrane model.
Int J Mol Med
; 10(6): 785-8, 2002 Dec.
Artigo
Inglês
| MEDLINE | ID: mdl-12430008
14.
CCL2/MCP-1 controls parasite burden, cell infiltration, and mononuclear activation during acute Trypanosoma cruzi infection.
J Leukoc Biol
; 86(5): 1239-46, 2009 Nov.
Artigo
Inglês
| MEDLINE | ID: mdl-19641038
15.
Unraveling the lethal synergism between Trypanosoma cruzi infection and LPS: a role for increased macrophage reactivity.
Eur J Immunol
; 37(5): 1355-64, 2007 May.
Artigo
Inglês
| MEDLINE | ID: mdl-17390393
16.
Proinflammatory and cytotoxic effects of hexadecylphosphocholine (miltefosine) against drug-resistant strains of Trypanosoma cruzi.
Antimicrob Agents Chemother
; 46(11): 3472-7, 2002 Nov.
Artigo
Inglês
| MEDLINE | ID: mdl-12384352