Detalhe da pesquisa
1.
The special unfolded protein response in plasma cells.
Immunol Rev
; 303(1): 35-51, 2021 09.
Artigo
Inglês
| MEDLINE | ID: mdl-34368957
2.
Increased activity of IRE1 improves the clinical presentation of EAE.
FASEB J
; 37(12): e23283, 2023 12.
Artigo
Inglês
| MEDLINE | ID: mdl-37983957
3.
An interdomain helix in IRE1α mediates the conformational change required for the sensor's activation.
J Biol Chem
; 296: 100781, 2021.
Artigo
Inglês
| MEDLINE | ID: mdl-34000298
4.
HSP-4/BiP expression in secretory cells is regulated by a developmental program and not by the unfolded protein response.
PLoS Biol
; 17(3): e3000196, 2019 03.
Artigo
Inglês
| MEDLINE | ID: mdl-30908491
5.
Protein disulfide isomerase A6 controls the decay of IRE1α signaling via disulfide-dependent association.
Mol Cell
; 53(4): 562-576, 2014 Feb 20.
Artigo
Inglês
| MEDLINE | ID: mdl-24508390
6.
A Bystander Mechanism Explains the Specific Phenotype of a Broadly Expressed Misfolded Protein.
PLoS Genet
; 12(12): e1006450, 2016 Dec.
Artigo
Inglês
| MEDLINE | ID: mdl-27926939
7.
Candidate genes that affect aging through protein homeostasis.
Adv Exp Med Biol
; 847: 45-72, 2015.
Artigo
Inglês
| MEDLINE | ID: mdl-25916585
8.
Orchestration of secretory protein folding by ER chaperones.
Biochim Biophys Acta
; 1833(11): 2410-24, 2013 Nov.
Artigo
Inglês
| MEDLINE | ID: mdl-23507200
9.
Natural genetic variation determines susceptibility to aggregation or toxicity in a C. elegans model for polyglutamine disease.
BMC Biol
; 11: 100, 2013 Sep 30.
Artigo
Inglês
| MEDLINE | ID: mdl-24079614
10.
Increased activity of IRE1 improves the clinical presentation of EAE.
bioRxiv
; 2023 Apr 20.
Artigo
Inglês
| MEDLINE | ID: mdl-37131811
11.
Destabilizing protein polymorphisms in the genetic background direct phenotypic expression of mutant SOD1 toxicity.
PLoS Genet
; 5(3): e1000399, 2009 Mar.
Artigo
Inglês
| MEDLINE | ID: mdl-19266020
12.
HspB1 Overexpression Improves Life Span and Stress Resistance in an Invertebrate Model.
J Gerontol A Biol Sci Med Sci
; 77(2): 268-275, 2022 02 03.
Artigo
Inglês
| MEDLINE | ID: mdl-34610126
13.
Protein homeostasis in models of aging and age-related conformational disease.
Adv Exp Med Biol
; 694: 138-59, 2010.
Artigo
Inglês
| MEDLINE | ID: mdl-20886762
14.
GRP94 is essential for mesoderm induction and muscle development because it regulates insulin-like growth factor secretion.
Mol Biol Cell
; 18(10): 3764-75, 2007 Oct.
Artigo
Inglês
| MEDLINE | ID: mdl-17634284
15.
The peptide-binding activity of GRP94 is regulated by calcium.
Biochem J
; 405(2): 233-41, 2007 Jul 15.
Artigo
Inglês
| MEDLINE | ID: mdl-17411420
16.
Multiple Molecular Mechanisms Rescue mtDNA Disease in C. elegans.
Cell Rep
; 22(12): 3115-3125, 2018 03 20.
Artigo
Inglês
| MEDLINE | ID: mdl-29562168
17.
Quality Control across Compartments-Connecting ERAD with Ribosomal Quality Control.
J Mol Biol
; 431(2): 142-144, 2019 01 18.
Artigo
Inglês
| MEDLINE | ID: mdl-30503927
18.
The stress of protein misfolding: from single cells to multicellular organisms.
Cold Spring Harb Perspect Biol
; 3(6)2011 Jun 01.
Artigo
Inglês
| MEDLINE | ID: mdl-21536706
19.
A cellular perspective on conformational disease: the role of genetic background and proteostasis networks.
Curr Opin Struct Biol
; 20(1): 23-32, 2010 Feb.
Artigo
Inglês
| MEDLINE | ID: mdl-20053547
20.
Hsp27 overexpression in the R6/2 mouse model of Huntington's disease: chronic neurodegeneration does not induce Hsp27 activation.
Hum Mol Genet
; 16(9): 1078-90, 2007 May 01.
Artigo
Inglês
| MEDLINE | ID: mdl-17360721