Detalhe da pesquisa
1.
Shorter Is Better: The α-(l)-Threofuranosyl Nucleic Acid Modification Improves Stability, Potency, Safety, and Ago2 Binding and Mitigates Off-Target Effects of Small Interfering RNAs.
J Am Chem Soc
; 145(36): 19691-19706, 2023 09 13.
Artigo
Inglês
| MEDLINE | ID: mdl-37638886
2.
siRNAs containing 2'-fluorinated Northern-methanocarbacyclic (2'-F-NMC) nucleotides: in vitro and in vivo RNAi activity and inability of mitochondrial polymerases to incorporate 2'-F-NMC NTPs.
Nucleic Acids Res
; 49(5): 2435-2449, 2021 03 18.
Artigo
Inglês
| MEDLINE | ID: mdl-33577685
3.
Role of a "Magic" Methyl: 2'-Deoxy-2'-α-F-2'-ß-C-methyl Pyrimidine Nucleotides Modulate RNA Interference Activity through Synergy with 5'-Phosphate Mimics and Mitigation of Off-Target Effects.
J Am Chem Soc
; 144(32): 14517-14534, 2022 08 17.
Artigo
Inglês
| MEDLINE | ID: mdl-35921401
4.
Constraining Solar Wind Heating Processes by Kinetic Properties of Heavy Ions.
Phys Rev Lett
; 116(25): 255101, 2016 Jun 24.
Artigo
Inglês
| MEDLINE | ID: mdl-27391732
5.
Metabolically Stable Anomeric Linkages Containing GalNAc-siRNA Conjugates: An Interplay among ASGPR, Glycosidase, and RISC Pathways.
J Med Chem
; 66(4): 2506-2523, 2023 02 23.
Artigo
Inglês
| MEDLINE | ID: mdl-36757090
6.
Neurofilament Light Chain as a Biomarker of Hereditary Transthyretin-Mediated Amyloidosis.
Neurology
; 96(3): e412-e422, 2021 01 19.
Artigo
Inglês
| MEDLINE | ID: mdl-33087494
7.
GDF11 Increases with Age and Inhibits Skeletal Muscle Regeneration.
Cell Metab
; 22(1): 164-74, 2015 Jul 07.
Artigo
Inglês
| MEDLINE | ID: mdl-26001423
8.
An HMGA2-IGF2BP2 axis regulates myoblast proliferation and myogenesis.
Dev Cell
; 23(6): 1176-88, 2012 Dec 11.
Artigo
Inglês
| MEDLINE | ID: mdl-23177649
9.
MESSENGER observations of the spatial distribution of planetary ions near Mercury.
Science
; 333(6051): 1862-5, 2011 Sep 30.
Artigo
Inglês
| MEDLINE | ID: mdl-21960628