Detalhe da pesquisa
1.
Impact of Deoxycholic Acid on Oesophageal Adenocarcinoma Invasion: Effect on Matrix Metalloproteinases.
Int J Mol Sci
; 21(21)2020 Oct 28.
Artigo
Inglês
| MEDLINE | ID: mdl-33126685
2.
Cardioprotective effect of MMP-2-inhibitor-NO-donor hybrid against ischaemia/reperfusion injury.
J Cell Mol Med
; 23(4): 2836-2848, 2019 04.
Artigo
Inglês
| MEDLINE | ID: mdl-30729745
3.
Novel Iron-Whey Protein Microspheres Protect Gut Epithelial Cells from Iron-Related Oxidative Stress and Damage and Improve Iron Absorption in Fasting Adults.
Acta Haematol
; 138(4): 223-232, 2017.
Artigo
Inglês
| MEDLINE | ID: mdl-29301124
4.
A fluorescent analogue of tauroursodeoxycholic acid reduces ER stress and is cytoprotective.
Bioorg Med Chem Lett
; 26(21): 5369-5372, 2016 11 01.
Artigo
Inglês
| MEDLINE | ID: mdl-27729186
5.
Novel Selective Butyrylcholinesterase Inhibitors Incorporating Antioxidant Functionalities as Potential Bimodal Therapeutics for Alzheimer's Disease.
Molecules
; 21(4): 440, 2016 Apr 01.
Artigo
Inglês
| MEDLINE | ID: mdl-27534722
6.
Nitric oxide-matrix metaloproteinase-9 interactions: biological and pharmacological significance--NO and MMP-9 interactions.
Biochim Biophys Acta
; 1843(3): 603-17, 2014 Mar.
Artigo
Inglês
| MEDLINE | ID: mdl-24333402
7.
Matrix metalloproteinases in inflammatory bowel disease: an update.
Mediators Inflamm
; 2015: 964131, 2015.
Artigo
Inglês
| MEDLINE | ID: mdl-25948887
8.
Mechanisms of platelet-stimulated colon cancer invasion: role of clusterin and thrombospondin 1 in regulation of the P38MAPK-MMP-9 pathway.
Carcinogenesis
; 35(2): 324-32, 2014 Feb.
Artigo
Inglês
| MEDLINE | ID: mdl-24085798
9.
New highly toxic bile acids derived from deoxycholic acid, chenodeoxycholic acid and lithocholic acid.
Bioorg Med Chem
; 22(1): 256-68, 2014 Jan 01.
Artigo
Inglês
| MEDLINE | ID: mdl-24332653
10.
Ursodeoxycholic acid attenuates colonic epithelial secretory function.
J Physiol
; 591(9): 2307-18, 2013 May 01.
Artigo
Inglês
| MEDLINE | ID: mdl-23507881
11.
MMP inhibition by barbiturate homodimers.
Bioorg Med Chem Lett
; 23(2): 444-7, 2013 Jan 15.
Artigo
Inglês
| MEDLINE | ID: mdl-23246356
12.
Synthesis and biological evaluation of Foscan® bile acid conjugates to target esophageal cancer cells.
Bioorg Med Chem Lett
; 23(9): 2495-9, 2013 May 01.
Artigo
Inglês
| MEDLINE | ID: mdl-23541647
13.
A nitrophenyl-based prodrug type for colorectal targeting of prednisolone, budesonide and celecoxib.
Bioorg Med Chem Lett
; 23(6): 1693-8, 2013 Mar 15.
Artigo
Inglês
| MEDLINE | ID: mdl-23416011
14.
Structure requirements for anaerobe processing of azo compounds: implications for prodrug design.
Bioorg Med Chem Lett
; 22(24): 7647-52, 2012 Dec 15.
Artigo
Inglês
| MEDLINE | ID: mdl-23122822
15.
Azo-reductase activated budesodine prodrugs for colon targeting.
Bioorg Med Chem Lett
; 22(24): 7573-7, 2012 Dec 15.
Artigo
Inglês
| MEDLINE | ID: mdl-23122819
16.
New fluorescent bile acids: synthesis, chemical characterization, and disastereoselective uptake by Caco-2 cells of 3-deoxy 3-NBD-amino deoxycholic and ursodeoxycholic acid.
Bioorg Med Chem
; 20(5): 1767-78, 2012 Mar 01.
Artigo
Inglês
| MEDLINE | ID: mdl-22316556
17.
A double prodrug system for colon targeting of benzenesulfonamide COX-2 inhibitors.
Bioorg Med Chem Lett
; 21(22): 6636-40, 2011 Nov 15.
Artigo
Inglês
| MEDLINE | ID: mdl-21983446
18.
N-substituted homopiperazine barbiturates as gelatinase inhibitors.
Bioorg Med Chem
; 19(16): 4985-99, 2011 Aug 15.
Artigo
Inglês
| MEDLINE | ID: mdl-21764590
19.
Secondary (iso)BAs cooperate with endogenous ligands to activate FXR under physiological and pathological conditions.
Biochim Biophys Acta Mol Basis Dis
; 1867(8): 166153, 2021 08 01.
Artigo
Inglês
| MEDLINE | ID: mdl-33895309
20.
Bile acid toxicity structure-activity relationships: correlations between cell viability and lipophilicity in a panel of new and known bile acids using an oesophageal cell line (HET-1A).
Bioorg Med Chem
; 18(18): 6886-95, 2010 Sep 15.
Artigo
Inglês
| MEDLINE | ID: mdl-20713311