Detalhe da pesquisa
1.
Methyl-tert-butyl ether (MTBE): integration of rat and mouse carcinogenicity data with mode of action and human and rodent bioassay dosimetry and toxicokinetics indicates MTBE is not a plausible human carcinogen.
J Toxicol Environ Health B Crit Rev
; 25(4): 135-161, 2022 05 19.
Artigo
Inglês
| MEDLINE | ID: mdl-35291916
2.
In vivo mutagenicity evaluation of the soil fumigant 1,3-dichloropropene.
Mutagenesis
; 35(5): 437-443, 2020 12 01.
Artigo
Inglês
| MEDLINE | ID: mdl-33511997
3.
Dose-Response for Multiple Biomarkers of Exposure and Genotoxic Effect Following Repeated Treatment of Rats with the Alkylating Agents, MMS and MNU.
Mutagenesis
; 31(3): 297-308, 2016 05.
Artigo
Inglês
| MEDLINE | ID: mdl-26040483
4.
Using gene expression profiling to evaluate cellular responses in mouse lungs exposed to V2O5 and a group of other mouse lung tumorigens and non-tumorigens.
Regul Toxicol Pharmacol
; 73(1): 339-47, 2015 Oct.
Artigo
Inglês
| MEDLINE | ID: mdl-26210822
5.
A novel approach for concurrent quantitation of glutathione, glutathione disulfide, and 2-hydroxyethylated glutathione in lungs of mice exposed to ethylene oxide, using liquid chromatography-positive electrospray tandem mass spectrometry.
Biomed Chromatogr
; 29(9): 1364-74, 2015 Sep.
Artigo
Inglês
| MEDLINE | ID: mdl-25641649
6.
A critical assessment of the methodologies to investigate the role of inhibition of apoptosis in rodent hepatocarcinogenesis.
Toxicol Mech Methods
; 25(3): 192-200, 2015 Mar.
Artigo
Inglês
| MEDLINE | ID: mdl-25608721
7.
Application of a novel integrated toxicity testing strategy incorporating "3R" principles of animal research to evaluate the safety of a new agrochemical sulfoxaflor.
Crit Rev Toxicol
; 44 Suppl 2: 1-14, 2014 May.
Artigo
Inglês
| MEDLINE | ID: mdl-24832550
8.
Human relevance framework for rodent liver tumors induced by the insecticide sulfoxaflor.
Crit Rev Toxicol
; 44 Suppl 2: 15-24, 2014 May.
Artigo
Inglês
| MEDLINE | ID: mdl-24832551
9.
Investigations on the genotoxic potential of styrene in Fischer 344 rats using multiple endpoints.
Environ Mol Mutagen
; 65(1-2): 67-75, 2024.
Artigo
Inglês
| MEDLINE | ID: mdl-38525651
10.
Severity of effect considerations regarding the use of mutation as a toxicological endpoint for risk assessment: A report from the 8th International Workshop on Genotoxicity Testing (IWGT).
Environ Mol Mutagen
; 2024 Jun 03.
Artigo
Inglês
| MEDLINE | ID: mdl-38828778
11.
An integrated approach for prospectively investigating a mode-of-action for rodent liver effects.
Toxicol Appl Pharmacol
; 270(2): 164-73, 2013 Jul 15.
Artigo
Inglês
| MEDLINE | ID: mdl-23607986
12.
Genotoxicity evaluation of orally administered styrene monomer in mice using comet, micronucleus, and Pig-a endpoints.
Environ Mol Mutagen
; 64(5): 282-290, 2023 06.
Artigo
Inglês
| MEDLINE | ID: mdl-37042435
13.
Investigation of the potential mutagenicity of ethyl tertiary-butyl ether in the tumor target tissue using transgenic Big Blue Fischer 344 rats following whole body inhalation exposure.
Environ Mol Mutagen
; 64(4): 244-249, 2023 04.
Artigo
Inglês
| MEDLINE | ID: mdl-36841967
14.
In vitro and in vivo assessments of the genotoxic potential of 3-chloroallyl alcohol.
Environ Mol Mutagen
; 64(1): 26-38, 2023 01.
Artigo
Inglês
| MEDLINE | ID: mdl-36314072
15.
Genetic damage, but limited evidence of oxidative stress markers in diethyl maleate-induced glutathione depleted mouse lymphoma L5178Y (TK(+/-)) cell cultures.
Toxicol Mech Methods
; 22(7): 547-54, 2012 Sep.
Artigo
Inglês
| MEDLINE | ID: mdl-22564015
16.
Epigenetic screening in product safety assessment: are we there yet?
Toxicol Mech Methods
; 21(4): 298-311, 2011 May.
Artigo
Inglês
| MEDLINE | ID: mdl-21495868
17.
A review of the genotoxicity of the industrial chemical cumene.
Mutat Res Rev Mutat Res
; 787: 108364, 2021.
Artigo
Inglês
| MEDLINE | ID: mdl-34083043
18.
Recommendations for conducting the rodent erythrocyte Pig-a assay: A report from the HESI GTTC Pig-a Workgroup.
Environ Mol Mutagen
; 62(3): 227-237, 2021 03.
Artigo
Inglês
| MEDLINE | ID: mdl-33608913
19.
Epigenetics and chemical safety assessment.
Mutat Res
; 705(2): 83-95, 2010 Oct.
Artigo
Inglês
| MEDLINE | ID: mdl-20399890
20.
Considerations for the Use of Mutation as a Regulatory Endpoint in Risk Assessment.
Environ Mol Mutagen
; 61(1): 84-93, 2020 01.
Artigo
Inglês
| MEDLINE | ID: mdl-31301246