Detalhe da pesquisa
1.
Structure-Based Discovery of A Small Molecule Inhibitor of Histone Deacetylase 6 (HDAC6) that Significantly Reduces Alzheimer's Disease Neuropathology.
Adv Sci (Weinh)
; 11(1): e2304545, 2024 Jan.
Artigo
Inglês
| MEDLINE | ID: mdl-37990786
2.
Molecular Imaging of Alzheimer's Disease-Related Sigma-1 Receptor in the Brain via a Novel Ru-Mediated Aromatic 18F-deoxyfluorination Probe.
J Med Chem
; 67(8): 6207-6217, 2024 Apr 25.
Artigo
Inglês
| MEDLINE | ID: mdl-38607332
3.
Early modulation of the gut microbiome by female sex hormones alters amyloid pathology and microglial function.
Sci Rep
; 14(1): 1827, 2024 01 21.
Artigo
Inglês
| MEDLINE | ID: mdl-38246956
4.
Sodium oligomannate alters gut microbiota, reduces cerebral amyloidosis and reactive microglia in a sex-specific manner.
Mol Neurodegener
; 19(1): 18, 2024 Feb 17.
Artigo
Inglês
| MEDLINE | ID: mdl-38365827
5.
Design, synthesis, and anti-inflammatory activity characterization of novel brain-permeable HDAC6 inhibitors.
Eur J Med Chem
; 254: 115327, 2023 Jun 05.
Artigo
Inglês
| MEDLINE | ID: mdl-37098307
6.
Development of a potential PET probe for HDAC6 imaging in Alzheimer's disease.
Acta Pharm Sin B
; 12(10): 3891-3904, 2022 Oct.
Artigo
Inglês
| MEDLINE | ID: mdl-36213537