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Rev Inst Med Trop Sao Paulo ; 58: 58, 2016 07 11.
Artigo em Inglês | MEDLINE | ID: mdl-27410918

RESUMO

The aim of this study was to investigate the association of EBV and HPV with gingivitis and/or periodontitis according to the immunologic status. To this end, 74 oral biopsies from transplanted and non-transplanted individuals with the abovementioned oral manifestations were submitted to a screening by PCR for both viruses. According to the results, EBV was strongly associated with gingivitis and/or periodontitis in transplanted individuals (p = 0.011) but not HPV (p = 0.766). EBV-HPV co-detections did not enhance the presence of tissue injury as well. Although a causal relationship was not investigated in this study, the higher frequency of these two oncoviruses in lesion tissues must be investigated in follow-up studies, especially among immunocompromised individuals.


Assuntos
Infecções por Vírus Epstein-Barr/diagnóstico , Gengivite/virologia , Transplante de Rim , Infecções por Papillomavirus/diagnóstico , Periodontite/virologia , Estudos de Casos e Controles , DNA Viral/genética , Gengivite/diagnóstico , Herpesvirus Humano 4/genética , Herpesvirus Humano 4/isolamento & purificação , Humanos , Papillomaviridae/genética , Papillomaviridae/isolamento & purificação , Periodontite/diagnóstico , Reação em Cadeia da Polimerase
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