Detalhe da pesquisa
1.
Targeting Pin1 renders pancreatic cancer eradicable by synergizing with immunochemotherapy.
Cell
; 184(18): 4753-4771.e27, 2021 09 02.
Artigo
Inglês
| MEDLINE | ID: mdl-34388391
2.
Allosteric Activators of Protein Phosphatase 2A Display Broad Antitumor Activity Mediated by Dephosphorylation of MYBL2.
Cell
; 181(3): 702-715.e20, 2020 04 30.
Artigo
Inglês
| MEDLINE | ID: mdl-32315619
3.
A Quantitative Tissue-Specific Landscape of Protein Redox Regulation during Aging.
Cell
; 180(5): 968-983.e24, 2020 03 05.
Artigo
Inglês
| MEDLINE | ID: mdl-32109415
4.
Mapping the Degradable Kinome Provides a Resource for Expedited Degrader Development.
Cell
; 183(6): 1714-1731.e10, 2020 12 10.
Artigo
Inglês
| MEDLINE | ID: mdl-33275901
5.
Structure of the Human cGAS-DNA Complex Reveals Enhanced Control of Immune Surveillance.
Cell
; 174(2): 300-311.e11, 2018 07 12.
Artigo
Inglês
| MEDLINE | ID: mdl-30007416
6.
Retraction Notice to: Allosteric Activators of Protein Phosphatase 2A Display Broad Antitumor Activity Mediated by Dephosphorylation of MYBL2.
Cell
; 185(16): 3058, 2022 08 04.
Artigo
Inglês
| MEDLINE | ID: mdl-35931023
7.
YY1 Is a Structural Regulator of Enhancer-Promoter Loops.
Cell
; 171(7): 1573-1588.e28, 2017 Dec 14.
Artigo
Inglês
| MEDLINE | ID: mdl-29224777
8.
A Next Generation Connectivity Map: L1000 Platform and the First 1,000,000 Profiles.
Cell
; 171(6): 1437-1452.e17, 2017 Nov 30.
Artigo
Inglês
| MEDLINE | ID: mdl-29195078
9.
A Landscape of Pharmacogenomic Interactions in Cancer.
Cell
; 166(3): 740-754, 2016 Jul 28.
Artigo
Inglês
| MEDLINE | ID: mdl-27397505
10.
CDK7-dependent transcriptional addiction in triple-negative breast cancer.
Cell
; 163(1): 174-86, 2015 Sep 24.
Artigo
Inglês
| MEDLINE | ID: mdl-26406377
11.
Targeting DCAF5 suppresses SMARCB1-mutant cancer by stabilizing SWI/SNF.
Nature
; 628(8007): 442-449, 2024 Apr.
Artigo
Inglês
| MEDLINE | ID: mdl-38538798
12.
CDK7 inhibition suppresses super-enhancer-linked oncogenic transcription in MYCN-driven cancer.
Cell
; 159(5): 1126-1139, 2014 Nov 20.
Artigo
Inglês
| MEDLINE | ID: mdl-25416950
13.
Rewiring cancer drivers to activate apoptosis.
Nature
; 620(7973): 417-425, 2023 Aug.
Artigo
Inglês
| MEDLINE | ID: mdl-37495688
14.
The evolving war on cancer.
Cell
; 145(1): 19-24, 2011 Apr 01.
Artigo
Inglês
| MEDLINE | ID: mdl-21458664
15.
CDK7 controls E2F- and MYC-driven proliferative and metabolic vulnerabilities in multiple myeloma.
Blood
; 141(23): 2841-2852, 2023 06 08.
Artigo
Inglês
| MEDLINE | ID: mdl-36877894
16.
Depletion of creatine phosphagen energetics with a covalent creatine kinase inhibitor.
Nat Chem Biol
; 19(7): 815-824, 2023 07.
Artigo
Inglês
| MEDLINE | ID: mdl-36823351
17.
BORIS promotes chromatin regulatory interactions in treatment-resistant cancer cells.
Nature
; 572(7771): 676-680, 2019 08.
Artigo
Inglês
| MEDLINE | ID: mdl-31391581
18.
Author Correction: Targeting DCAF5 suppresses SMARCB1-mutant cancer by stabilizing SWI/SNF.
Nature
; 629(8012): E12, 2024 May.
Artigo
Inglês
| MEDLINE | ID: mdl-38684813
19.
BET Bromodomain Proteins Function as Master Transcription Elongation Factors Independent of CDK9 Recruitment.
Mol Cell
; 67(1): 5-18.e19, 2017 Jul 06.
Artigo
Inglês
| MEDLINE | ID: mdl-28673542
20.
A preclinical platform for assessing antitumor effects and systemic toxicities of cancer drug targets.
Proc Natl Acad Sci U S A
; 119(17): e2110557119, 2022 04 26.
Artigo
Inglês
| MEDLINE | ID: mdl-35442775