Detalhe da pesquisa
1.
A Landscape of Pharmacogenomic Interactions in Cancer.
Cell
; 166(3): 740-754, 2016 Jul 28.
Artigo
Inglês
| MEDLINE | ID: mdl-27397505
2.
TAK1 inhibition promotes apoptosis in KRAS-dependent colon cancers.
Cell
; 148(4): 639-50, 2012 Feb 17.
Artigo
Inglês
| MEDLINE | ID: mdl-22341439
3.
Catastrophic ATP loss underlies a metabolic combination therapy tailored for MYCN-amplified neuroblastoma.
Proc Natl Acad Sci U S A
; 118(13)2021 03 30.
Artigo
Inglês
| MEDLINE | ID: mdl-33762304
4.
BRAF and AXL oncogenes drive RIPK3 expression loss in cancer.
PLoS Biol
; 16(8): e2005756, 2018 08.
Artigo
Inglês
| MEDLINE | ID: mdl-30157175
5.
Genome-wide prediction of synthetic rescue mediators of resistance to targeted and immunotherapy.
Mol Syst Biol
; 15(3): e8323, 2019 03 11.
Artigo
Inglês
| MEDLINE | ID: mdl-30858180
6.
Systematic identification of genomic markers of drug sensitivity in cancer cells.
Nature
; 483(7391): 570-5, 2012 Mar 28.
Artigo
Inglês
| MEDLINE | ID: mdl-22460902
7.
Genomics of Drug Sensitivity in Cancer (GDSC): a resource for therapeutic biomarker discovery in cancer cells.
Nucleic Acids Res
; 41(Database issue): D955-61, 2013 Jan.
Artigo
Inglês
| MEDLINE | ID: mdl-23180760
8.
Targeting aberrant glutathione metabolism to eradicate human acute myelogenous leukemia cells.
J Biol Chem
; 288(47): 33542-33558, 2013 Nov 22.
Artigo
Inglês
| MEDLINE | ID: mdl-24089526
9.
SULT1A1-dependent sulfonation of alkylators is a lineage-dependent vulnerability of liver cancers.
Nat Cancer
; 4(3): 365-381, 2023 03.
Artigo
Inglês
| MEDLINE | ID: mdl-36914816
10.
A landscape of response to drug combinations in non-small cell lung cancer.
Nat Commun
; 14(1): 3830, 2023 06 28.
Artigo
Inglês
| MEDLINE | ID: mdl-37380628
11.
Pharmacological blockade of TEAD-YAP reveals its therapeutic limitation in cancer cells.
Nat Commun
; 13(1): 6744, 2022 11 08.
Artigo
Inglês
| MEDLINE | ID: mdl-36347861
12.
High-risk neuroblastoma with NF1 loss of function is targetable using SHP2 inhibition.
Cell Rep
; 40(4): 111095, 2022 07 26.
Artigo
Inglês
| MEDLINE | ID: mdl-35905710
13.
IFITM proteins assist cellular uptake of diverse linked chemotypes.
Science
; 378(6624): 1097-1104, 2022 12 09.
Artigo
Inglês
| MEDLINE | ID: mdl-36480603
14.
EGFR Inhibition Potentiates FGFR Inhibitor Therapy and Overcomes Resistance in FGFR2 Fusion-Positive Cholangiocarcinoma.
Cancer Discov
; 12(5): 1378-1395, 2022 05 02.
Artigo
Inglês
| MEDLINE | ID: mdl-35420673
15.
Pharmacologic Inhibition of SHP2 Blocks Both PI3K and MEK Signaling in Low-epiregulin HNSCC via GAB1.
Cancer Res Commun
; 2(9): 1061-1074, 2022 09.
Artigo
Inglês
| MEDLINE | ID: mdl-36506869
16.
Venetoclax-based Rational Combinations are Effective in Models of MYCN-amplified Neuroblastoma.
Mol Cancer Ther
; 20(8): 1400-1411, 2021 08.
Artigo
Inglês
| MEDLINE | ID: mdl-34088831
17.
Screening and Validation of Molecular Targeted Radiosensitizers.
Int J Radiat Oncol Biol Phys
; 111(5): e63-e74, 2021 12 01.
Artigo
Inglês
| MEDLINE | ID: mdl-34343607
18.
Identification of genotype-correlated sensitivity to selective kinase inhibitors by using high-throughput tumor cell line profiling.
Proc Natl Acad Sci U S A
; 104(50): 19936-41, 2007 Dec 11.
Artigo
Inglês
| MEDLINE | ID: mdl-18077425
19.
Pharmacological Targeting of Vacuolar H+-ATPase via Subunit V1G Combats Multidrug-Resistant Cancer.
Cell Chem Biol
; 27(11): 1359-1370.e8, 2020 11 19.
Artigo
Inglês
| MEDLINE | ID: mdl-32649904
20.
KRAS G12C NSCLC Models Are Sensitive to Direct Targeting of KRAS in Combination with PI3K Inhibition.
Clin Cancer Res
; 25(2): 796-807, 2019 01 15.
Artigo
Inglês
| MEDLINE | ID: mdl-30327306