Detalhe da pesquisa
1.
DNA damage in oocytes induces a switch of the quality control factor TAp63α from dimer to tetramer.
Cell
; 144(4): 566-76, 2011 Feb 18.
Artigo
Inglês
| MEDLINE | ID: mdl-21335238
2.
Retroviral gene therapy in Germany with a view on previous experience and future perspectives.
Gene Ther
; 28(9): 494-512, 2021 09.
Artigo
Inglês
| MEDLINE | ID: mdl-33753908
3.
Targeting HSP90 dimerization via the C terminus is effective in imatinib-resistant CML and lacks the heat shock response.
Blood
; 132(3): 307-320, 2018 07 19.
Artigo
Inglês
| MEDLINE | ID: mdl-29724897
4.
A small, portable RNA device for the control of exon skipping in mammalian cells.
Nucleic Acids Res
; 46(8): e48, 2018 05 04.
Artigo
Inglês
| MEDLINE | ID: mdl-29420816
5.
MiR144/451 Expression Is Repressed by RUNX1 During Megakaryopoiesis and Disturbed by RUNX1/ETO.
PLoS Genet
; 12(3): e1005946, 2016 Mar.
Artigo
Inglês
| MEDLINE | ID: mdl-26990877
6.
A minimal ubiquitous chromatin opening element (UCOE) effectively prevents silencing of juxtaposed heterologous promoters by epigenetic remodeling in multipotent and pluripotent stem cells.
Nucleic Acids Res
; 43(3): 1577-92, 2015 Feb 18.
Artigo
Inglês
| MEDLINE | ID: mdl-25605798
7.
Hyperinflammation in patients with chronic granulomatous disease leads to impairment of hematopoietic stem cell functions.
J Allergy Clin Immunol
; 138(1): 219-228.e9, 2016 07.
Artigo
Inglês
| MEDLINE | ID: mdl-26853280
8.
CD133-targeted gene transfer into long-term repopulating hematopoietic stem cells.
Mol Ther
; 23(1): 63-70, 2015 Jan.
Artigo
Inglês
| MEDLINE | ID: mdl-25189742
9.
Selective inhibition of tumor growth by clonal NK cells expressing an ErbB2/HER2-specific chimeric antigen receptor.
Mol Ther
; 23(2): 330-8, 2015 Feb.
Artigo
Inglês
| MEDLINE | ID: mdl-25373520
10.
A new level of regulation in gluconeogenesis: metabolic state modulates the intracellular localization of aldolase B and its interaction with liver fructose-1,6-bisphosphatase.
Biochem J
; 472(2): 225-37, 2015 Dec 01.
Artigo
Inglês
| MEDLINE | ID: mdl-26417114
11.
Dual-regulated lentiviral vector for gene therapy of X-linked chronic granulomatosis.
Mol Ther
; 22(8): 1472-1483, 2014 Aug.
Artigo
Inglês
| MEDLINE | ID: mdl-24869932
12.
A bispecific transmembrane antibody simultaneously targeting intra- and extracellular epitopes of the epidermal growth factor receptor inhibits receptor activation and tumor cell growth.
Int J Cancer
; 134(11): 2547-59, 2014 Jun 01.
Artigo
Inglês
| MEDLINE | ID: mdl-24243620
13.
Engineered factor IX variants bypass FVIII and correct hemophilia A phenotype in mice.
Blood
; 119(2): 602-11, 2012 Jan 12.
Artigo
Inglês
| MEDLINE | ID: mdl-22031860
14.
SOCS1 cooperates with FLT3-ITD in the development of myeloproliferative disease by promoting the escape from external cytokine control.
Blood
; 120(8): 1691-702, 2012 Aug 23.
Artigo
Inglês
| MEDLINE | ID: mdl-22517899
15.
A ubiquitous chromatin opening element prevents transgene silencing in pluripotent stem cells and their differentiated progeny.
Stem Cells
; 31(3): 488-99, 2013 Mar.
Artigo
Inglês
| MEDLINE | ID: mdl-23307570
16.
Alpharetroviral vector-mediated gene therapy for X-CGD: functional correction and lack of aberrant splicing.
Mol Ther
; 21(3): 648-61, 2013 Mar.
Artigo
Inglês
| MEDLINE | ID: mdl-23207695
17.
Stably integrated and expressed retroviral sequences can influence nuclear location and chromatin condensation of the integration locus.
Chromosoma
; 121(4): 353-67, 2012 Aug.
Artigo
Inglês
| MEDLINE | ID: mdl-22415776
18.
Safer, silencing-resistant lentiviral vectors: optimization of the ubiquitous chromatin-opening element through elimination of aberrant splicing.
J Virol
; 86(17): 9088-95, 2012 Sep.
Artigo
Inglês
| MEDLINE | ID: mdl-22696657
19.
Clonal analysis of multipotent stromal cells derived from CD271+ bone marrow mononuclear cells: functional heterogeneity and different mechanisms of allosuppression.
Haematologica
; 98(10): 1609-16, 2013 Oct.
Artigo
Inglês
| MEDLINE | ID: mdl-23975178
20.
From determinants of RUNX1/ETO tetramerization to small-molecule protein-protein interaction inhibitors targeting acute myeloid leukemia.
J Chem Inf Model
; 53(9): 2197-202, 2013 Sep 23.
Artigo
Inglês
| MEDLINE | ID: mdl-23957251