Detalhe da pesquisa
1.
A phase I, randomized, double-blind, placebo-controlled, ascending single- and multiple-dose study of the pharmacokinetics, safety, and tolerability of oral ceftibuten in healthy adult subjects.
Antimicrob Agents Chemother
; 68(1): e0109923, 2024 Jan 10.
Artigo
Inglês
| MEDLINE | ID: mdl-38059635
2.
A Phase 1 Study of the Safety, Tolerability, and Pharmacokinetics of Biapenem in Healthy Adult Subjects.
Antimicrob Agents Chemother
; 65(5)2023 05 01.
Artigo
Inglês
| MEDLINE | ID: mdl-33685898
3.
Broad-spectrum cyclic boronate ß-lactamase inhibitors featuring an intramolecular prodrug for oral bioavailability.
Bioorg Med Chem
; 62: 116722, 2022 05 15.
Artigo
Inglês
| MEDLINE | ID: mdl-35358864
4.
Activity of Aerosolized Levofloxacin against Burkholderia cepacia in a Mouse Model of Chronic Lung Infection.
Antimicrob Agents Chemother
; 64(2)2020 01 27.
Artigo
Inglês
| MEDLINE | ID: mdl-31712215
5.
In Vivo Activity of QPX7728, an Ultrabroad-Spectrum Beta-Lactamase Inhibitor, in Combination with Beta-Lactams against Carbapenem-Resistant Klebsiella pneumoniae.
Antimicrob Agents Chemother
; 64(11)2020 10 20.
Artigo
Inglês
| MEDLINE | ID: mdl-32839224
6.
Pharmacodynamics of Meropenem against Acinetobacter baumannii in a Neutropenic Mouse Thigh Infection Model.
Antimicrob Agents Chemother
; 64(4)2020 03 24.
Artigo
Inglês
| MEDLINE | ID: mdl-31988101
7.
Activity of Meropenem-Vaborbactam against Pseudomonas aeruginosa and Acinetobacter baumannii in a Neutropenic Mouse Thigh Infection Model.
Antimicrob Agents Chemother
; 63(1)2019 01.
Artigo
Inglês
| MEDLINE | ID: mdl-30323049
8.
Pharmacodynamics of Minocycline against Acinetobacter baumannii in a Rat Pneumonia Model.
Antimicrob Agents Chemother
; 63(2)2019 02.
Artigo
Inglês
| MEDLINE | ID: mdl-30397059
9.
Pharmacokinetics/Pharmacodynamics of Vaborbactam, a Novel Beta-Lactamase Inhibitor, in Combination with Meropenem.
Antimicrob Agents Chemother
; 63(1)2019 01.
Artigo
Inglês
| MEDLINE | ID: mdl-30397063
10.
A Retrospective Cohort Analysis Shows that Coadministration of Minocycline with Colistin in Critically Ill Patients Is Associated with Reduced Frequency of Acute Renal Failure.
Antimicrob Agents Chemother
; 62(1)2018 01.
Artigo
Inglês
| MEDLINE | ID: mdl-29038261
11.
Phase 1 Study of the Safety, Tolerability, and Pharmacokinetics of Vaborbactam and Meropenem Alone and in Combination following Single and Multiple Doses in Healthy Adult Subjects.
Antimicrob Agents Chemother
; 62(4)2018 04.
Artigo
Inglês
| MEDLINE | ID: mdl-29437614
12.
Single-Dose Pharmacokinetics and Safety of Meropenem-Vaborbactam in Subjects with Chronic Renal Impairment.
Antimicrob Agents Chemother
; 62(3)2018 03.
Artigo
Inglês
| MEDLINE | ID: mdl-29311069
13.
Activity of Meropenem-Vaborbactam in Mouse Models of Infection Due to KPC-Producing Carbapenem-Resistant Enterobacteriaceae.
Antimicrob Agents Chemother
; 62(1)2018 01.
Artigo
Inglês
| MEDLINE | ID: mdl-29109160
14.
Activity of Simulated Human Dosage Regimens of Meropenem and Vaborbactam against Carbapenem-Resistant Enterobacteriaceae in an In Vitro Hollow-Fiber Model.
Antimicrob Agents Chemother
; 62(2)2018 02.
Artigo
Inglês
| MEDLINE | ID: mdl-29133570
15.
Activity of Meropenem-Vaborbactam against Carbapenem-Resistant Enterobacteriaceae in a Murine Model of Pyelonephritis.
Antimicrob Agents Chemother
; 62(1)2018 01.
Artigo
Inglês
| MEDLINE | ID: mdl-29038270
16.
Vaborbactam: Spectrum of Beta-Lactamase Inhibition and Impact of Resistance Mechanisms on Activity in Enterobacteriaceae.
Antimicrob Agents Chemother
; 61(11)2017 11.
Artigo
Inglês
| MEDLINE | ID: mdl-28848018
17.
Caring for youth living with HIV across the continuum: turning gaps into opportunities.
AIDS Care
; 29(10): 1205-1211, 2017 10.
Artigo
Inglês
| MEDLINE | ID: mdl-28278569
18.
Phase 1 Study of the Safety, Tolerability, and Pharmacokinetics of the ß-Lactamase Inhibitor Vaborbactam (RPX7009) in Healthy Adult Subjects.
Antimicrob Agents Chemother
; 60(10): 6326-32, 2016 10.
Artigo
Inglês
| MEDLINE | ID: mdl-27527080
19.
Meropenem-RPX7009 Concentrations in Plasma, Epithelial Lining Fluid, and Alveolar Macrophages of Healthy Adult Subjects.
Antimicrob Agents Chemother
; 59(12): 7232-9, 2015 Dec.
Artigo
Inglês
| MEDLINE | ID: mdl-26349830
20.
A synthetic lipopeptide targeting top-priority multidrug-resistant Gram-negative pathogens.
Nat Commun
; 13(1): 1625, 2022 03 25.
Artigo
Inglês
| MEDLINE | ID: mdl-35338128