Detalhe da pesquisa
1.
Milestones to the Discovery of T-type Calcium Channel Blockers for the Treatment of Generalized Epilepsies.
Chimia (Aarau)
; 71(10): 722-729, 2017 Oct 25.
Artigo
Inglês
| MEDLINE | ID: mdl-29070417
2.
Design and optimization of new piperidines as renin inhibitors.
Bioorg Med Chem Lett
; 20(21): 6286-90, 2010 Nov 01.
Artigo
Inglês
| MEDLINE | ID: mdl-20843686
3.
Piperidine-based renin inhibitors: upper chain optimization.
Bioorg Med Chem Lett
; 20(21): 6291-6, 2010 Nov 01.
Artigo
Inglês
| MEDLINE | ID: mdl-20843690
4.
New classes of potent and bioavailable human renin inhibitors.
Bioorg Med Chem Lett
; 19(23): 6762-5, 2009 Dec 01.
Artigo
Inglês
| MEDLINE | ID: mdl-19853442
5.
Preparation, Antiepileptic Activity, and Cardiovascular Safety of Dihydropyrazoles as Brain-Penetrant T-Type Calcium Channel Blockers.
J Med Chem
; 59(18): 8398-411, 2016 Sep 22.
Artigo
Inglês
| MEDLINE | ID: mdl-27579577
6.
Discovery and Characterization of ACT-451840: an Antimalarial Drug with a Novel Mechanism of Action.
ChemMedChem
; 11(18): 1995-2014, 2016 09 20.
Artigo
Inglês
| MEDLINE | ID: mdl-27471138
7.
Novel benzo[1,4]diazepin-2-one derivatives as endothelin receptor antagonists.
J Med Chem
; 47(11): 2776-95, 2004 May 20.
Artigo
Inglês
| MEDLINE | ID: mdl-15139756
8.
Design and preparation of potent, nonpeptidic, bioavailable renin inhibitors.
J Med Chem
; 52(12): 3689-702, 2009 Jun 25.
Artigo
Inglês
| MEDLINE | ID: mdl-19358611
9.
Inhibitors of Plasmepsin II-potential antimalarial agents.
Bioorg Med Chem Lett
; 16(24): 6194-9, 2006 Dec 15.
Artigo
Inglês
| MEDLINE | ID: mdl-17000102
10.
Development of alpha-keto-based inhibitors of cruzain, a cysteine protease implicated in Chagas disease.
Bioorg Med Chem
; 13(6): 2141-56, 2005 Mar 15.
Artigo
Inglês
| MEDLINE | ID: mdl-15727867
11.
Achiral, cheap, and potent inhibitors of Plasmepsins I, II, and IV.
ChemMedChem
; 1(12): 1341-5, 2006 Dec.
Artigo
Inglês
| MEDLINE | ID: mdl-17091526