Detalhe da pesquisa
1.
The fungal expel of 5-fluorocytosine derived fluoropyrimidines mitigates its antifungal activity and generates a cytotoxic environment.
PLoS Pathog
; 18(12): e1011066, 2022 12.
Artigo
Inglês
| MEDLINE | ID: mdl-36574449
2.
The cytochrome P450 reductase CprA is a rate-limiting factor for Cyp51A-mediated azole resistance in Aspergillus fumigatus.
Antimicrob Agents Chemother
; 67(11): e0091823, 2023 11 15.
Artigo
Inglês
| MEDLINE | ID: mdl-37815358
3.
The fungal CCAAT-binding complex and HapX display highly variable but evolutionary conserved synergetic promoter-specific DNA recognition.
Nucleic Acids Res
; 48(7): 3567-3590, 2020 04 17.
Artigo
Inglês
| MEDLINE | ID: mdl-32086516
4.
The Zn2Cys6-type transcription factor LeuB cross-links regulation of leucine biosynthesis and iron acquisition in Aspergillus fumigatus.
PLoS Genet
; 14(10): e1007762, 2018 10.
Artigo
Inglês
| MEDLINE | ID: mdl-30365497
5.
The bZIP Transcription Factor HapX Is Post-Translationally Regulated to Control Iron Homeostasis in Aspergillus fumigatus.
Int J Mol Sci
; 22(14)2021 Jul 20.
Artigo
Inglês
| MEDLINE | ID: mdl-34299357
6.
Mechanistic Basis of pH-Dependent 5-Flucytosine Resistance in Aspergillus fumigatus.
Antimicrob Agents Chemother
; 62(6)2018 06.
Artigo
Inglês
| MEDLINE | ID: mdl-29610197
7.
The Janus transcription factor HapX controls fungal adaptation to both iron starvation and iron excess.
EMBO J
; 33(19): 2261-76, 2014 Oct 01.
Artigo
Inglês
| MEDLINE | ID: mdl-25092765
8.
Correction: Sterol Biosynthesis and Azole Tolerance Is Governed by the Opposing Actions of SrbA and the CCAAT Binding Complex.
PLoS Pathog
; 12(12): e1006106, 2016 Dec.
Artigo
Inglês
| MEDLINE | ID: mdl-27973537
9.
Sterol Biosynthesis and Azole Tolerance Is Governed by the Opposing Actions of SrbA and the CCAAT Binding Complex.
PLoS Pathog
; 12(7): e1005775, 2016 07.
Artigo
Inglês
| MEDLINE | ID: mdl-27438727
10.
Anti-Aspergillus activities of olorofim at sub-MIC levels during early-stage growth.
Microbiol Spectr
; 12(3): e0330423, 2024 Mar 05.
Artigo
Inglês
| MEDLINE | ID: mdl-38315027
11.
Aspergillus fumigatus SidJ mediates intracellular siderophore hydrolysis.
Appl Environ Microbiol
; 79(23): 7534-6, 2013 Dec.
Artigo
Inglês
| MEDLINE | ID: mdl-24038704
12.
Quantifying Isoprenoids in the Ergosterol Biosynthesis by Gas Chromatography-Mass Spectrometry.
J Fungi (Basel)
; 9(7)2023 Jul 20.
Artigo
Inglês
| MEDLINE | ID: mdl-37504756
13.
HapX-mediated adaption to iron starvation is crucial for virulence of Aspergillus fumigatus.
PLoS Pathog
; 6(9): e1001124, 2010 Sep 30.
Artigo
Inglês
| MEDLINE | ID: mdl-20941352
14.
Modular Inducible Multigene Expression System for Filamentous Fungi.
Microbiol Spectr
; 10(6): e0367022, 2022 12 21.
Artigo
Inglês
| MEDLINE | ID: mdl-36350143
15.
Azole Resistance-Associated Regulatory Motifs within the Promoter of cyp51A in Aspergillus fumigatus.
Microbiol Spectr
; 10(3): e0120922, 2022 06 29.
Artigo
Inglês
| MEDLINE | ID: mdl-35575535
16.
Uptake of the Siderophore Triacetylfusarinine C, but Not Fusarinine C, Is Crucial for Virulence of Aspergillus fumigatus.
mBio
; 13(5): e0219222, 2022 10 26.
Artigo
Inglês
| MEDLINE | ID: mdl-36125294
17.
Antagonism of the Azoles to Olorofim and Cross-Resistance Are Governed by Linked Transcriptional Networks in Aspergillus fumigatus.
mBio
; 13(6): e0221522, 2022 12 20.
Artigo
Inglês
| MEDLINE | ID: mdl-36286521
18.
The Siderophore Transporters Sit1 and Sit2 Are Essential for Utilization of Ferrichrome-, Ferrioxamine- and Coprogen-Type Siderophores in Aspergillus fumigatus.
J Fungi (Basel)
; 7(9)2021 Sep 16.
Artigo
Inglês
| MEDLINE | ID: mdl-34575806
19.
Antifungal Siderophore Conjugates for Theranostic Applications in Invasive Pulmonary Aspergillosis Using Low-Molecular TAFC Scaffolds.
J Fungi (Basel)
; 7(7)2021 Jul 14.
Artigo
Inglês
| MEDLINE | ID: mdl-34356941
20.
Inducible Selectable Marker Genes to Improve Aspergillus fumigatus Genetic Manipulation.
J Fungi (Basel)
; 7(7)2021 Jun 24.
Artigo
Inglês
| MEDLINE | ID: mdl-34202756