Detalhe da pesquisa
1.
Rebound growth of BRAF mutant pediatric glioma cells after MAPKi withdrawal is associated with MAPK reactivation and secretion of microglia-recruiting cytokines.
J Neurooncol
; 2024 Apr 17.
Artigo
Inglês
| MEDLINE | ID: mdl-38630384
2.
Zoledronic acid enhances tumor growth and metastatic spread in a mouse model of jaw osteosarcoma.
Oral Dis
; 2024 Feb 20.
Artigo
Inglês
| MEDLINE | ID: mdl-38376129
3.
Cell senescence in neuropathology: A focus on neurodegeneration and tumours.
Neuropathol Appl Neurobiol
; 47(3): 359-378, 2021 04.
Artigo
Inglês
| MEDLINE | ID: mdl-33378554
4.
Tumour compartment transcriptomics demonstrates the activation of inflammatory and odontogenic programmes in human adamantinomatous craniopharyngioma and identifies the MAPK/ERK pathway as a novel therapeutic target.
Acta Neuropathol
; 135(5): 757-777, 2018 05.
Artigo
Inglês
| MEDLINE | ID: mdl-29541918
5.
In vitro and in vivo discrepancy in inducing apoptosis by mesenchymal stromal cells delivering membrane-bound tumor necrosis factor-related apoptosis inducing ligand in osteosarcoma pre-clinical models.
Cytotherapy
; 20(8): 1037-1045, 2018 08.
Artigo
Inglês
| MEDLINE | ID: mdl-30093324
6.
TRAIL delivered by mesenchymal stromal/stem cells counteracts tumor development in orthotopic Ewing sarcoma models.
Int J Cancer
; 139(12): 2802-2811, 2016 Dec 15.
Artigo
Inglês
| MEDLINE | ID: mdl-27558972
7.
TRAIL-based therapy in pediatric bone tumors: how to overcome resistance.
Future Oncol
; 11(3): 535-42, 2015.
Artigo
Inglês
| MEDLINE | ID: mdl-25675131
8.
Development of a DNA damage-induced senescence model in osteoarthritic chondrocytes.
Aging (Albany NY)
; 15(17): 8576-8593, 2023 09 01.
Artigo
Inglês
| MEDLINE | ID: mdl-37659108
9.
COPI vesicle formation and N-myristoylation are targetable vulnerabilities of senescent cells.
Nat Cell Biol
; 25(12): 1804-1820, 2023 Dec.
Artigo
Inglês
| MEDLINE | ID: mdl-38012402
10.
BH3 mimetics targeting BCL-XL impact the senescent compartment of pilocytic astrocytoma.
Neuro Oncol
; 25(4): 735-747, 2023 04 06.
Artigo
Inglês
| MEDLINE | ID: mdl-35977048
11.
Clearance of senescent macrophages ameliorates tumorigenesis in KRAS-driven lung cancer.
Cancer Cell
; 41(7): 1242-1260.e6, 2023 07 10.
Artigo
Inglês
| MEDLINE | ID: mdl-37267953
12.
TRAIL-Based Therapies Efficacy in Pediatric Bone Tumors Models Is Modulated by TRAIL Non-Apoptotic Pathway Activation via RIPK1 Recruitment.
Cancers (Basel)
; 14(22)2022 Nov 16.
Artigo
Inglês
| MEDLINE | ID: mdl-36428719
13.
Galactose-modified duocarmycin prodrugs as senolytics.
Aging Cell
; 19(4): e13133, 2020 04.
Artigo
Inglês
| MEDLINE | ID: mdl-32175667
14.
The Senescence-associated Secretory Phenotype Mediates Oncogene-induced Senescence in Pediatric Pilocytic Astrocytoma.
Clin Cancer Res
; 25(6): 1851-1866, 2019 03 15.
Artigo
Inglês
| MEDLINE | ID: mdl-30530705
15.
Cardiac glycosides are broad-spectrum senolytics.
Nat Metab
; 1(11): 1074-1088, 2019 11.
Artigo
Inglês
| MEDLINE | ID: mdl-31799499
16.
Bone microenvironment has an influence on the histological response of osteosarcoma to chemotherapy: retrospective analysis and preclinical modeling.
Am J Cancer Res
; 7(11): 2333-2349, 2017.
Artigo
Inglês
| MEDLINE | ID: mdl-29218254
17.
L-MTP-PE and zoledronic acid combination in osteosarcoma: preclinical evidence of positive therapeutic combination for clinical transfer.
Am J Cancer Res
; 6(3): 677-89, 2016.
Artigo
Inglês
| MEDLINE | ID: mdl-27152244
18.
Clusterin inhibition using OGX-011 synergistically enhances zoledronic acid activity in osteosarcoma.
Oncotarget
; 5(17): 7805-19, 2014 Sep 15.
Artigo
Inglês
| MEDLINE | ID: mdl-25138053
19.
A functional, new short isoform of death receptor 4 in Ewing's sarcoma cell lines may be involved in TRAIL sensitivity/resistance mechanisms.
Mol Cancer Res
; 10(3): 336-46, 2012 Mar.
Artigo
Inglês
| MEDLINE | ID: mdl-22258765