Detalhe da pesquisa
1.
Let's make microglia great again in neurodegenerative disorders.
J Neural Transm (Vienna)
; 125(5): 751-770, 2018 05.
Artigo
Inglês
| MEDLINE | ID: mdl-29027011
2.
α-Secretase-derived fragment of cellular prion, N1, protects against monomeric and oligomeric amyloid ß (Aß)-associated cell death.
J Biol Chem
; 287(7): 5021-32, 2012 Feb 10.
Artigo
Inglês
| MEDLINE | ID: mdl-22184125
3.
Acute Stress, Induced by IFNγ + Aß, and Chronic Stress, Induced by Age, Affect Microglia in a Sex-Specific Manner.
Mol Neurobiol
; 60(6): 3044-3053, 2023 Jun.
Artigo
Inglês
| MEDLINE | ID: mdl-36781739
4.
The extracellular regulated kinase-1 (ERK1) controls regulated alpha-secretase-mediated processing, promoter transactivation, and mRNA levels of the cellular prion protein.
J Biol Chem
; 286(33): 29192-29206, 2011 Aug 19.
Artigo
Inglês
| MEDLINE | ID: mdl-21586567
5.
Microglial metabolism is a pivotal factor in sexual dimorphism in Alzheimer's disease.
Commun Biol
; 4(1): 711, 2021 06 10.
Artigo
Inglês
| MEDLINE | ID: mdl-34112929
6.
The alpha-secretase-derived N-terminal product of cellular prion, N1, displays neuroprotective function in vitro and in vivo.
J Biol Chem
; 284(51): 35973-86, 2009 Dec 18.
Artigo
Inglês
| MEDLINE | ID: mdl-19850936
7.
p53-dependent control of cell death by nicastrin: lack of requirement for presenilin-dependent gamma-secretase complex.
J Neurochem
; 109(1): 225-37, 2009 Apr.
Artigo
Inglês
| MEDLINE | ID: mdl-19187441
8.
The NLRP3 inflammasome modulates glycolysis by increasing PFKFB3 in an IL-1ß-dependent manner in macrophages.
Sci Rep
; 9(1): 4034, 2019 03 11.
Artigo
Inglês
| MEDLINE | ID: mdl-30858427
9.
TMP21 regulates Abeta production but does not affect caspase-3, p53, and neprilysin.
Biochem Biophys Res Commun
; 371(1): 69-74, 2008 Jun 20.
Artigo
Inglês
| MEDLINE | ID: mdl-18405662
10.
Regulation of betaAPP and PrPc cleavage by alpha-secretase: mechanistic and therapeutic perspectives.
Curr Alzheimer Res
; 5(2): 202-11, 2008 Apr.
Artigo
Inglês
| MEDLINE | ID: mdl-18393805
11.
Quantitative 3D In Silico Modeling (q3DISM) of Cerebral Amyloid-beta Phagocytosis in Rodent Models of Alzheimer's Disease.
J Vis Exp
; (118)2016 12 26.
Artigo
Inglês
| MEDLINE | ID: mdl-28060279
12.
Innate Immunity Fights Alzheimer's Disease.
Trends Neurosci
; 38(11): 674-681, 2015 Nov.
Artigo
Inglês
| MEDLINE | ID: mdl-26549882
13.
The role of the immune system in neurodegenerative disorders: Adaptive or maladaptive?
Brain Res
; 1617: 155-73, 2015 Aug 18.
Artigo
Inglês
| MEDLINE | ID: mdl-25218556
14.
Il10 deficiency rebalances innate immunity to mitigate Alzheimer-like pathology.
Neuron
; 85(3): 534-48, 2015 Feb 04.
Artigo
Inglês
| MEDLINE | ID: mdl-25619654
15.
Innate immunity in Alzheimer's disease: a complex affair.
CNS Neurol Disord Drug Targets
; 12(5): 593-607, 2013 Aug.
Artigo
Inglês
| MEDLINE | ID: mdl-23574177
16.
Brain injury, neuroinflammation and Alzheimer's disease.
Front Aging Neurosci
; 5: 26, 2013.
Artigo
Inglês
| MEDLINE | ID: mdl-23874297
17.
Ferulic acid is a nutraceutical ß-secretase modulator that improves behavioral impairment and alzheimer-like pathology in transgenic mice.
PLoS One
; 8(2): e55774, 2013.
Artigo
Inglês
| MEDLINE | ID: mdl-23409038