Detalhe da pesquisa
1.
Noncovalent inhibition of C481S Bruton tyrosine kinase by GDC-0853: a new treatment strategy for ibrutinib-resistant CLL.
Blood
; 132(10): 1039-1049, 2018 09 06.
Artigo
Inglês
| MEDLINE | ID: mdl-30018078
2.
Selinexor is effective in acquired resistance to ibrutinib and synergizes with ibrutinib in chronic lymphocytic leukemia.
Blood
; 125(20): 3128-32, 2015 May 14.
Artigo
Inglês
| MEDLINE | ID: mdl-25838351
3.
IPI-145 antagonizes intrinsic and extrinsic survival signals in chronic lymphocytic leukemia cells.
Blood
; 124(24): 3583-6, 2014 Dec 04.
Artigo
Inglês
| MEDLINE | ID: mdl-25258342
4.
Assessing Information Gaps Associated with Initial Pediatric Study Plans for New Oncology Drug and Biological Products.
Clin Pharmacol Ther
; 114(3): 618-622, 2023 09.
Artigo
Inglês
| MEDLINE | ID: mdl-37422730
5.
US FDA Postmarketing Requirements and Commitments: A Systematic Assessment of Clinical Pharmacology Studies and Their Impact on US FDA Prescribing Information.
J Clin Pharmacol
; 63(6): 695-703, 2023 06.
Artigo
Inglês
| MEDLINE | ID: mdl-36731882
6.
Informing a Comprehensive Risk Assessment of Infant Drug Exposure From Human Milk: Application of a Physiologically Based Pharmacokinetic Lactation Model for Sotalol.
J Clin Pharmacol
; 63 Suppl 1: S106-S116, 2023 06.
Artigo
Inglês
| MEDLINE | ID: mdl-37317500
7.
Pharmacokinetic Evaluation in Pregnancy-Current Status and Future Considerations: Workshop Summary.
J Clin Pharmacol
; 63 Suppl 1: S7-S17, 2023 06.
Artigo
Inglês
| MEDLINE | ID: mdl-37317499
8.
Efficiency of a randomized confirmatory basket trial design constrained to control the family wise error rate by indication.
Stat Methods Med Res
; 31(7): 1207-1223, 2022 07.
Artigo
Inglês
| MEDLINE | ID: mdl-35404188
9.
Roadmap to 2030 for Drug Evaluation in Older Adults.
Clin Pharmacol Ther
; 112(2): 210-223, 2022 08.
Artigo
Inglês
| MEDLINE | ID: mdl-34656074
10.
Elucidating the Impact of Immunogenicity Assessment Postapproval: A Targeted Analysis of Immunogenicity Postmarketing Requirements and Commitments.
Clin Pharmacol Ther
; 109(3): 697-704, 2021 03.
Artigo
Inglês
| MEDLINE | ID: mdl-32895941
11.
A Systematic Assessment of US Food and Drug Administration Dosing Recommendations For Drug Development Programs Amenable to Response-Guided Titration.
Clin Pharmacol Ther
; 109(1): 123-130, 2021 01.
Artigo
Inglês
| MEDLINE | ID: mdl-33022770
12.
Reasons for Premature Conclusion of Late Phase Clinical Trials: An Analysis of ClinicalTrials.gov Registered Phase III Trials.
Ther Innov Regul Sci
; 54(1): 232-239, 2020 01.
Artigo
Inglês
| MEDLINE | ID: mdl-32008239
13.
Communicating Immunogenicity-Associated Risk in Current U.S. FDA Prescription Drug Labeling: A Systematic Evaluation.
Ther Innov Regul Sci
; 54(6): 1363-1371, 2020 11.
Artigo
Inglês
| MEDLINE | ID: mdl-33258100
14.
Exploring the Knowledge Gaps in Infant Drug Exposure From Human Milk: A Clinical Pharmacology Perspective.
J Clin Pharmacol
; 63(3): 273-276, 2023 03.
Artigo
Inglês
| MEDLINE | ID: mdl-36355399
15.
Assessing Pharmacokinetics in Liver Disease: Challenges and Future Considerations for Classification of Hepatic Dysfunction and Use of In Silico Methods.
J Clin Pharmacol
; 63(7): 755-758, 2023 07.
Artigo
Inglês
| MEDLINE | ID: mdl-36905192
16.
The regulation of tumor-suppressive microRNA, miR-126, in chronic lymphocytic leukemia.
Cancer Med
; 6(4): 778-787, 2017 Apr.
Artigo
Inglês
| MEDLINE | ID: mdl-28299881
17.
BTKC481S-Mediated Resistance to Ibrutinib in Chronic Lymphocytic Leukemia.
J Clin Oncol
; 35(13): 1437-1443, 2017 May 01.
Artigo
Inglês
| MEDLINE | ID: mdl-28418267
18.
Evaluation of time-dependent toxicity and combined effects for a series of mono-halogenated acetonitrile-containing binary mixtures.
Toxicol Rep
; 3: 572-583, 2016.
Artigo
Inglês
| MEDLINE | ID: mdl-28090437
19.
Assessing function of electronic health records for real-world data generation.
BMJ Evid Based Med
; 24(3): 95-98, 2019 Jun.
Artigo
Inglês
| MEDLINE | ID: mdl-30478146
20.
Time-dependence in mixture toxicity prediction.
Toxicology
; 326: 153-63, 2014 Dec 04.
Artigo
Inglês
| MEDLINE | ID: mdl-25446331