Detalhe da pesquisa
1.
CRISPR/Cas9-based targeted genome editing for correction of recessive dystrophic epidermolysis bullosa using iPS cells.
Proc Natl Acad Sci U S A
; 116(52): 26846-26852, 2019 Dec 26.
Artigo
Inglês
| MEDLINE | ID: mdl-31818947
2.
Site-specific genome editing for correction of induced pluripotent stem cells derived from dominant dystrophic epidermolysis bullosa.
Proc Natl Acad Sci U S A
; 113(20): 5676-81, 2016 May 17.
Artigo
Inglês
| MEDLINE | ID: mdl-27143720
3.
A scalable, GMP-compatible, autologous organotypic cell therapy for Dystrophic Epidermolysis Bullosa.
bioRxiv
; 2023 Mar 01.
Artigo
Inglês
| MEDLINE | ID: mdl-36909618
4.
Engineering human skin model innervated with itch sensory neuron-like cells differentiated from induced pluripotent stem cells.
Bioeng Transl Med
; 7(1): e10247, 2022 Jan.
Artigo
Inglês
| MEDLINE | ID: mdl-35111948
5.
A multi-organ chip with matured tissue niches linked by vascular flow.
Nat Biomed Eng
; 6(4): 351-371, 2022 04.
Artigo
Inglês
| MEDLINE | ID: mdl-35478225
6.
Recapitulating T cell infiltration in 3D psoriatic skin models for patient-specific drug testing.
Sci Rep
; 10(1): 4123, 2020 03 05.
Artigo
Inglês
| MEDLINE | ID: mdl-32139717
7.
Tissue engineering of human hair follicles using a biomimetic developmental approach.
Nat Commun
; 9(1): 5301, 2018 12 13.
Artigo
Inglês
| MEDLINE | ID: mdl-30546011
8.
A two-stage, p16(INK4A)- and p53-dependent keratinocyte senescence mechanism that limits replicative potential independent of telomere status.
Mol Cell Biol
; 22(14): 5157-72, 2002 Jul.
Artigo
Inglês
| MEDLINE | ID: mdl-12077343
9.
Next generation human skin constructs as advanced tools for drug development.
Exp Biol Med (Maywood)
; 242(17): 1657-1668, 2017 11.
Artigo
Inglês
| MEDLINE | ID: mdl-28592171
10.
Human Skin Constructs with Spatially Controlled Vasculature Using Primary and iPSC-Derived Endothelial Cells.
Adv Healthc Mater
; 5(14): 1800-7, 2016 07.
Artigo
Inglês
| MEDLINE | ID: mdl-27333469
11.
Targeting the Jak/Signal Transducer and Activator of Transcription 3 Pathway with Ruxolitinib in a Mouse Model of Recessive Dystrophic Epidermolysis Bullosa-Squamous Cell Carcinoma.
J Invest Dermatol
; 141(4): 942-946, 2021 04.
Artigo
Inglês
| MEDLINE | ID: mdl-33069729
12.
Pumpless microfluidic platform for drug testing on human skin equivalents.
Lab Chip
; 15(3): 882-8, 2015 Feb 07.
Artigo
Inglês
| MEDLINE | ID: mdl-25490891
13.
Melanin Transfer in Human 3D Skin Equivalents Generated Exclusively from Induced Pluripotent Stem Cells.
PLoS One
; 10(8): e0136713, 2015.
Artigo
Inglês
| MEDLINE | ID: mdl-26308443
14.
Challenges and promises in modeling dermatologic disorders with bioengineered skin.
Exp Biol Med (Maywood)
; 239(9): 1215-24, 2014 Sep.
Artigo
Inglês
| MEDLINE | ID: mdl-24951469
15.
Induced pluripotent stem cells from human revertant keratinocytes for the treatment of epidermolysis bullosa.
Sci Transl Med
; 6(264): 264ra164, 2014 Nov 26.
Artigo
Inglês
| MEDLINE | ID: mdl-25429057
16.
Generation of 3D skin equivalents fully reconstituted from human induced pluripotent stem cells (iPSCs).
PLoS One
; 8(10): e77673, 2013.
Artigo
Inglês
| MEDLINE | ID: mdl-24147053
17.
Building a microphysiological skin model from induced pluripotent stem cells.
Stem Cell Res Ther
; 4 Suppl 1: S2, 2013.
Artigo
Inglês
| MEDLINE | ID: mdl-24564920
18.
Tetraploid cells from cytokinesis failure induce aneuploidy and spontaneous transformation of mouse ovarian surface epithelial cells.
Cell Cycle
; 11(15): 2864-75, 2012 Aug 01.
Artigo
Inglês
| MEDLINE | ID: mdl-22801546
19.
Lagging chromosomes entrapped in micronuclei are not 'lost' by cells.
Cell Res
; 22(5): 932-5, 2012 May.
Artigo
Inglês
| MEDLINE | ID: mdl-22349462
20.
A keratinocyte hypermotility/growth-arrest response involving laminin 5 and p16INK4A activated in wound healing and senescence.
Am J Pathol
; 168(6): 1821-37, 2006 Jun.
Artigo
Inglês
| MEDLINE | ID: mdl-16723698