Detalhe da pesquisa
1.
The mutational landscapes of genetic and chemical models of Kras-driven lung cancer.
Nature
; 517(7535): 489-92, 2015 Jan 22.
Artigo
Inglês
| MEDLINE | ID: mdl-25363767
2.
ARF suppresses hepatic vascular neoplasia in a carcinogen-exposed murine model.
J Pathol
; 227(3): 298-305, 2012 Jul.
Artigo
Inglês
| MEDLINE | ID: mdl-22430984
3.
Pathway-specific tumor suppression. Reduction of p27 accelerates gastrointestinal tumorigenesis in Apc mutant mice, but not in Smad3 mutant mice.
Cancer Cell
; 1(4): 355-68, 2002 May.
Artigo
Inglês
| MEDLINE | ID: mdl-12086850
4.
Synthetic lethal kinases in Ras/p53 mutant squamous cell carcinoma.
Oncogene
; 41(24): 3355-3369, 2022 06.
Artigo
Inglês
| MEDLINE | ID: mdl-35538224
5.
DNA-PK suppresses a p53-independent apoptotic response to DNA damage.
EMBO Rep
; 10(1): 87-93, 2009 Jan.
Artigo
Inglês
| MEDLINE | ID: mdl-19057578
6.
Targeting BET Proteins BRD2 and BRD3 in Combination with PI3K-AKT Inhibition as a Therapeutic Strategy for Ovarian Clear Cell Carcinoma.
Mol Cancer Ther
; 20(4): 691-703, 2021 04.
Artigo
Inglês
| MEDLINE | ID: mdl-33509905
7.
BET, SRC, and BCL2 family inhibitors are synergistic drug combinations with PARP inhibitors in ovarian cancer.
EBioMedicine
; 60: 102988, 2020 Oct.
Artigo
Inglês
| MEDLINE | ID: mdl-32927276
8.
Endocrine dysfunction in p27Kip1 deficient mice and susceptibility to Wnt-1 driven breast cancer.
Carcinogenesis
; 30(6): 1058-63, 2009 Jun.
Artigo
Inglês
| MEDLINE | ID: mdl-19380520
9.
Tumor suppression by p53 in the absence of Atm.
Mol Cancer Res
; 6(7): 1185-92, 2008 Jul.
Artigo
Inglês
| MEDLINE | ID: mdl-18583527
10.
Ataxia-telangiectasia mutated is not required for p53 induction and apoptosis in irradiated epithelial tissues.
Mol Cancer Res
; 5(12): 1312-8, 2007 Dec.
Artigo
Inglês
| MEDLINE | ID: mdl-18171989
11.
Functional Precision Medicine Identifies Novel Druggable Targets and Therapeutic Options in Head and Neck Cancer.
Clin Cancer Res
; 24(12): 2828-2843, 2018 06 15.
Artigo
Inglês
| MEDLINE | ID: mdl-29599409
12.
p19Arf suppresses growth, progression, and metastasis of Hras-driven carcinomas through p53-dependent and -independent pathways.
PLoS Biol
; 2(8): E242, 2004 Aug.
Artigo
Inglês
| MEDLINE | ID: mdl-15314658
13.
Synergy between Prkdc and Trp53 regulates stem cell proliferation and GI-ARS after irradiation.
Cell Death Differ
; 24(11): 1853-1860, 2017 11.
Artigo
Inglês
| MEDLINE | ID: mdl-28686579
14.
Deficiency in the gap junction protein connexin32 alters p27Kip1 tumor suppression and MAPK activation in a tissue-specific manner.
Oncogene
; 24(10): 1718-26, 2005 Mar 03.
Artigo
Inglês
| MEDLINE | ID: mdl-15608667
15.
Distinct roles for p53, p27Kip1, and p21Cip1 during tumor development.
Oncogene
; 23(4): 905-13, 2004 Jan 29.
Artigo
Inglês
| MEDLINE | ID: mdl-14647411
16.
Induction of Liver Tumors in Mice with N-Ethyl-N-Nitrosourea or N-Nitrosodiethylamine.
Cold Spring Harb Protoc
; 2015(10): 941-2, 2015 Oct 01.
Artigo
Inglês
| MEDLINE | ID: mdl-26430250
17.
Induction of Colon Cancer in Mice with 1,2-Dimethylhydrazine.
Cold Spring Harb Protoc
; 2015(9): pdb.prot077453, 2015 Sep 01.
Artigo
Inglês
| MEDLINE | ID: mdl-26330619
18.
Induction of Lung Tumors in Mice with Urethane.
Cold Spring Harb Protoc
; 2015(9): pdb.prot077446, 2015 Sep 01.
Artigo
Inglês
| MEDLINE | ID: mdl-26330618
19.
Functional kinomics identifies candidate therapeutic targets in head and neck cancer.
Clin Cancer Res
; 20(16): 4274-88, 2014 Aug 15.
Artigo
Inglês
| MEDLINE | ID: mdl-25125259
20.
CTCF haploinsufficiency destabilizes DNA methylation and predisposes to cancer.
Cell Rep
; 7(4): 1020-9, 2014 May 22.
Artigo
Inglês
| MEDLINE | ID: mdl-24794443