Detalhe da pesquisa
1.
Obesity Drives STAT-1-Dependent NASH and STAT-3-Dependent HCC.
Cell
; 175(5): 1289-1306.e20, 2018 11 15.
Artigo
Inglês
| MEDLINE | ID: mdl-30454647
2.
Insulin-Binding Peptide Probes Provide a Novel Strategy for Pancreatic ß-Cell Imaging.
Mol Pharm
; 18(12): 4428-4436, 2021 12 06.
Artigo
Inglês
| MEDLINE | ID: mdl-34649437
3.
Star Polymers Reduce Islet Amyloid Polypeptide Toxicity via Accelerated Amyloid Aggregation.
Biomacromolecules
; 18(12): 4249-4260, 2017 Dec 11.
Artigo
Inglês
| MEDLINE | ID: mdl-29035554
4.
Inhibition of hIAPP Amyloid Aggregation and Pancreatic ß-Cell Toxicity by OH-Terminated PAMAM Dendrimer.
Small
; 12(12): 1615-26, 2016 Mar 23.
Artigo
Inglês
| MEDLINE | ID: mdl-26808649
5.
Graphene oxide inhibits hIAPP amyloid fibrillation and toxicity in insulin-producing NIT-1 cells.
Phys Chem Chem Phys
; 18(1): 94-100, 2016 Jan 07.
Artigo
Inglês
| MEDLINE | ID: mdl-26625841
6.
HAMSAB diet ameliorates dysfunctional signaling in pancreatic islets in autoimmune diabetes.
iScience
; 27(1): 108694, 2024 Jan 19.
Artigo
Inglês
| MEDLINE | ID: mdl-38213620
7.
Exposure to the viral by-product dsRNA or Coxsackievirus B5 triggers pancreatic beta cell apoptosis via a Bim / Mcl-1 imbalance.
PLoS Pathog
; 7(9): e1002267, 2011 Sep.
Artigo
Inglês
| MEDLINE | ID: mdl-21977009
8.
Inhibition of RIPK1 kinase does not affect diabetes development: ß-Cells survive RIPK1 activation.
Mol Metab
; 69: 101681, 2023 03.
Artigo
Inglês
| MEDLINE | ID: mdl-36707047
9.
Non-alcoholic fatty liver disease and diabetes mellitus as growing aetiologies of hepatocellular carcinoma.
JHEP Rep
; 5(9): 100811, 2023 Sep.
Artigo
Inglês
| MEDLINE | ID: mdl-37575883
10.
STAT1 is a master regulator of pancreatic {beta}-cell apoptosis and islet inflammation.
J Biol Chem
; 286(2): 929-41, 2011 Jan 14.
Artigo
Inglês
| MEDLINE | ID: mdl-20980260
11.
Cytokines tumor necrosis factor-α and interferon-γ induce pancreatic ß-cell apoptosis through STAT1-mediated Bim protein activation.
J Biol Chem
; 286(45): 39632-43, 2011 Nov 11.
Artigo
Inglês
| MEDLINE | ID: mdl-21937453
12.
MDA5 and PTPN2, two candidate genes for type 1 diabetes, modify pancreatic beta-cell responses to the viral by-product double-stranded RNA.
Hum Mol Genet
; 19(1): 135-46, 2010 Jan 01.
Artigo
Inglês
| MEDLINE | ID: mdl-19825843
13.
Nova1 or Bim Deficiency in Pancreatic ß-Cells Does Not Alter Multiple Low-Dose Streptozotocin-Induced Diabetes and Diet-Induced Obesity in Mice.
Nutrients
; 14(18)2022 Sep 18.
Artigo
Inglês
| MEDLINE | ID: mdl-36145242
14.
PTPN2 Regulates the Interferon Signaling and Endoplasmic Reticulum Stress Response in Pancreatic ß-Cells in Autoimmune Diabetes.
Diabetes
; 71(4): 653-668, 2022 04 01.
Artigo
Inglês
| MEDLINE | ID: mdl-35044456
15.
Metabolite-based dietary supplementation in human type 1 diabetes is associated with microbiota and immune modulation.
Microbiome
; 10(1): 9, 2022 01 19.
Artigo
Inglês
| MEDLINE | ID: mdl-35045871
16.
p53 up-regulated modulator of apoptosis (PUMA) activation contributes to pancreatic beta-cell apoptosis induced by proinflammatory cytokines and endoplasmic reticulum stress.
J Biol Chem
; 285(26): 19910-20, 2010 Jun 25.
Artigo
Inglês
| MEDLINE | ID: mdl-20421300
17.
Oxidative stress in obesity-associated hepatocellular carcinoma: sources, signaling and therapeutic challenges.
Oncogene
; 40(33): 5155-5167, 2021 08.
Artigo
Inglês
| MEDLINE | ID: mdl-34290399
18.
STAT3 Regulates Mitochondrial Gene Expression in Pancreatic ß-Cells and Its Deficiency Induces Glucose Intolerance in Obesity.
Diabetes
; 70(9): 2026-2041, 2021 09.
Artigo
Inglês
| MEDLINE | ID: mdl-34183374
19.
Novel Strategies to Protect and Visualize Pancreatic ß Cells in Diabetes.
Trends Endocrinol Metab
; 31(12): 905-917, 2020 12.
Artigo
Inglês
| MEDLINE | ID: mdl-33160815
20.
Sweet Killing in Obesity and Diabetes: The Metabolic Role of the BH3-only Protein BIM.
J Mol Biol
; 430(18 Pt B): 3041-3050, 2018 09 14.
Artigo
Inglês
| MEDLINE | ID: mdl-30036494