Detalhe da pesquisa
1.
Cellular senescence: at the nexus between ageing and diabetes.
Diabetologia
; 62(10): 1835-1841, 2019 10.
Artigo
Inglês
| MEDLINE | ID: mdl-31451866
2.
WISP2 regulates preadipocyte commitment and PPARγ activation by BMP4.
Proc Natl Acad Sci U S A
; 110(7): 2563-8, 2013 Feb 12.
Artigo
Inglês
| MEDLINE | ID: mdl-23359679
3.
Type 2 Diabetes, Independent of Obesity and Age, Is Characterized by Senescent and Dysfunctional Mature Human Adipose Cells.
Diabetes
; 71(11): 2372-2383, 2022 11 01.
Artigo
Inglês
| MEDLINE | ID: mdl-36006465
4.
ZMAT3 hypomethylation contributes to early senescence of preadipocytes from healthy first-degree relatives of type 2 diabetics.
Aging Cell
; 21(3): e13557, 2022 03.
Artigo
Inglês
| MEDLINE | ID: mdl-35146866
5.
Activation of canonical wingless-type MMTV integration site family (Wnt) signaling in mature adipocytes increases beta-catenin levels and leads to cell dedifferentiation and insulin resistance.
J Biol Chem
; 285(18): 14031-41, 2010 Apr 30.
Artigo
Inglês
| MEDLINE | ID: mdl-20179324
6.
Inflammation and impaired adipogenesis in hypertrophic obesity in man.
Am J Physiol Endocrinol Metab
; 297(5): E999-E1003, 2009 Nov.
Artigo
Inglês
| MEDLINE | ID: mdl-19622783
7.
Reduced subcutaneous adipogenesis in human hypertrophic obesity is linked to senescent precursor cells.
Nat Commun
; 10(1): 2757, 2019 06 21.
Artigo
Inglês
| MEDLINE | ID: mdl-31227697
8.
Inflamed adipose tissue: a culprit underlying the metabolic syndrome and atherosclerosis.
Arterioscler Thromb Vasc Biol
; 27(11): 2276-83, 2007 Nov.
Artigo
Inglês
| MEDLINE | ID: mdl-17823366
9.
TP53INP2 regulates adiposity by activating ß-catenin through autophagy-dependent sequestration of GSK3ß.
Nat Cell Biol
; 20(4): 443-454, 2018 04.
Artigo
Inglês
| MEDLINE | ID: mdl-29593329
10.
Regulation of white adipogenesis and its relation to ectopic fat accumulation and cardiovascular risk.
Atherosclerosis
; 241(1): 27-35, 2015 Jul.
Artigo
Inglês
| MEDLINE | ID: mdl-25957567
11.
Insulin resistance and impaired adipogenesis.
Trends Endocrinol Metab
; 26(4): 193-200, 2015 Apr.
Artigo
Inglês
| MEDLINE | ID: mdl-25703677
12.
BMP4 and BMP Antagonists Regulate Human White and Beige Adipogenesis.
Diabetes
; 64(5): 1670-81, 2015 May.
Artigo
Inglês
| MEDLINE | ID: mdl-25605802
13.
The WNT inhibitor Dickkopf 1 and bone morphogenetic protein 4 rescue adipogenesis in hypertrophic obesity in humans.
Diabetes
; 61(5): 1217-24, 2012 May.
Artigo
Inglês
| MEDLINE | ID: mdl-22447857
14.
Adipose tissue, inflammation and atherosclerosis.
J Atheroscler Thromb
; 17(4): 332-41, 2010 Apr 30.
Artigo
Inglês
| MEDLINE | ID: mdl-20124732
15.
Impaired preadipocyte differentiation in human abdominal obesity: role of Wnt, tumor necrosis factor-alpha, and inflammation.
Diabetes
; 58(7): 1550-7, 2009 Jul.
Artigo
Inglês
| MEDLINE | ID: mdl-19351711
16.
Restricted adipogenesis in hypertrophic obesity: the role of WISP2, WNT, and BMP4.
Diabetes
; 62(9): 2997-3004, 2013 Sep.
Artigo
Inglês
| MEDLINE | ID: mdl-23970518
17.
Inflamed adipose tissue, insulin resistance and vascular injury.
Diabetes Metab Res Rev
; 24(8): 595-603, 2008.
Artigo
Inglês
| MEDLINE | ID: mdl-18756581
18.
Wnt-signaling is maintained and adipogenesis inhibited by TNFalpha but not MCP-1 and resistin.
Biochem Biophys Res Commun
; 357(3): 700-6, 2007 Jun 08.
Artigo
Inglês
| MEDLINE | ID: mdl-17442272
19.
Cytokines promote Wnt signaling and inflammation and impair the normal differentiation and lipid accumulation in 3T3-L1 preadipocytes.
J Biol Chem
; 281(14): 9507-16, 2006 Apr 07.
Artigo
Inglês
| MEDLINE | ID: mdl-16464856
20.
Adiponectin gene activation by thiazolidinediones requires PPAR gamma 2, but not C/EBP alpha-evidence for differential regulation of the aP2 and adiponectin genes.
Biochem Biophys Res Commun
; 308(4): 933-9, 2003 Sep 05.
Artigo
Inglês
| MEDLINE | ID: mdl-12927809