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1.
Radiat Prot Dosimetry ; 125(1-4): 209-12, 2007.
Artigo em Inglês | MEDLINE | ID: mdl-16980706

RESUMO

A moderator-type neutron monitor containing pairs of TLD 600/700 elements (Harshaw) modified with the addition of a lead layer (GSI ball) for the measurement of the ambient dose equivalent from neutrons at medium- and high-energy accelerators, is introduced in this work. Measurements were performed with the Gesellschaft für Schwerionenforschung (GSI) ball as well as with conventional polyethylene (PE) spheres at the high-energy accelerator SPS at European Organization for Nuclear Research [CERN (CERF)] and in Cave A of the heavy-ion synchrotron SIS at GSI. The measured dose values are compared with dose values derived from calculated neutron spectra folded with dose conversion coefficients. The estimated reading of the spheres calculated by means of the response functions and the neutron spectra is also included in the comparison. The analysis of the measurements shows that the PE/Pb sphere gives an improved estimate on the ambient dose equivalent of the neutron radiation transmitted through shielding of medium- and high-energy accelerators.


Assuntos
Aceleradores de Partículas/instrumentação , Monitoramento de Radiação/instrumentação , Proteção Radiológica/instrumentação , Desenho de Equipamento , Análise de Falha de Equipamento , Internacionalidade , Nêutrons , Doses de Radiação , Reprodutibilidade dos Testes , Sensibilidade e Especificidade
2.
Radiat Prot Dosimetry ; 126(1-4): 615-8, 2007.
Artigo em Inglês | MEDLINE | ID: mdl-17522032

RESUMO

High-energy (12)C ions offer favourable conditions for the treatment of deep-seated local tumours. Several facilities for the heavy ion therapy are planned or under construction, for example the new clinical ion-therapy unit HIT at the Radiological University Clinics in Heidelberg. In order to improve existing treatment planning models, it is essential to evaluate the secondary fragment production and to include these contributions to the therapy dose with higher accuracy. Secondary neutrons are most abundantly produced in the reactions between (12)C beams and tissues. The dose contribution to tissues by a neutron is fairly small compared with the projectile and the other charged fragments due to no ionisation and the small reaction cross-sections; however, it distributes in a considerably wider region beyond the bragg-peak because of the strong penetrability. Systematic data on energy spectra and doses of secondary neutrons produced by (12)C beams using water targets of different thicknesses for various detection angles have therefore been measured in this study at GSI Darmstadt.


Assuntos
Radioisótopos de Carbono/uso terapêutico , Radioterapia com Íons Pesados , Modelos Biológicos , Nêutrons , Radiometria/métodos , Planejamento da Radioterapia Assistida por Computador/métodos , Água/química , Simulação por Computador , Humanos , Dosagem Radioterapêutica
3.
Radiat Prot Dosimetry ; 126(1-4): 546-8, 2007.
Artigo em Inglês | MEDLINE | ID: mdl-17561518

RESUMO

At high-energy particle accelerators, area monitoring needs to be performed in a wide range of neutron energies. In principle, neutrons occur from thermal energies up to the energy of the accelerated ions, which is for the present GSI (Gesellschaft für Schwerionenforschung) accelerator facility approximately 1-2 GeV per nucleon. There are no passive dosemeters available, which are designed for the use at high-energy accelerators. At GSI, a neutron dosemeter was developed, which is suitable for the measurement of high-energy neutron radiation by the insertion of a lead layer around Thermoluminescence (TL) detection elements (pairs of TL 600/700) at the centre of the dosemeter. The design of the sphere was derived from the construction of the extended range rem-counters for the measurement of ambient dose equivalent H(10). In this work, the dosemeter fluence response was measured in the quasi-monoenergetic neutron fields of the accelerator facility of the PTB in Braunschweig and in the thermal neutron field of the GKSS research reactor FRG-1 in Geesthacht. For the accelerator measurements, the reactions (7)Li(p,n)(7)Be, (3)H(p,n)(3)He and (2)H(d,n)(3)He were used to produce neutron fields with energy peaks between 144 keV and 19 MeV. The measured fluence responses are 27% too low for thermal energies and show an agreement with approximately 14% for the accelerator produced neutron fields related to the computed fluence responses (MCNP, FLUKA calculations). The measured as well as the computed fluence responses of the dosemeter are compared with the corresponding conversion coefficients.


Assuntos
Nêutrons , Exposição Ocupacional/análise , Aceleradores de Partículas/instrumentação , Monitoramento de Radiação/instrumentação , Proteção Radiológica/instrumentação , Relação Dose-Resposta à Radiação , Desenho de Equipamento , Análise de Falha de Equipamento , Doses de Radiação , Monitoramento de Radiação/métodos , Proteção Radiológica/métodos , Reprodutibilidade dos Testes , Sensibilidade e Especificidade
4.
Radiat Prot Dosimetry ; 126(1-4): 497-500, 2007.
Artigo em Inglês | MEDLINE | ID: mdl-17519242

RESUMO

Experiments were performed in Cave C of GSI (Gesellschaft für Schwerionenforschung) using the LAND (Large Area Neutron Detector) in combination with the deflection magnet ALADIN (A LArge DIpol magNet) in front of the LAND where charged particles and neutrons can be separated. This arrangement is used to create high-energetic neutron fields by irradiation of a thick lead target (5 cm) with deuteron beams with the energies of 500 or 800 MeV per nucleon. In break-up reactions the neutron is separated from the proton which is deflected in the magnetic field of the ALADIN. The produced neutron radiation, which has a pronounced peak at the nucleon energy, is used to measure the fluence response of the GSI neutron ball. A thermoluminescence (TL) based spherical neutron dosemeter was developed for the area monitoring for the quantity H(10) at high-energy accelerators. In the same experiment, the spectral neutron fluence Phi(E) is measured with the LAND in the energy range from 100 MeV to 1 GeV. The measured fluence responses are compared with results of FLUKA calculations and the corresponding fluence-to-dose conversion coefficients. The measured dosemeter responses are too high in comparison to the calculated ones (up to approximately 50%), the dosemeter reading gives dose values which are too high by a factor of 1.1-2.2 related to the corresponding fluence-to-dose conversion factors.


Assuntos
Nêutrons , Monitoramento de Radiação/instrumentação , Proteção Radiológica/instrumentação , Desenho de Equipamento , Análise de Falha de Equipamento , Doses de Radiação , Monitoramento de Radiação/métodos , Proteção Radiológica/métodos , Reprodutibilidade dos Testes , Sensibilidade e Especificidade
5.
Radiat Prot Dosimetry ; 115(1-4): 212-5, 2005.
Artigo em Inglês | MEDLINE | ID: mdl-16381714

RESUMO

The Gesellschaft für Schwerionenforschung (GSI) is planning a significant expansion of its accelerator facilities. Compared to the present GSI facility, a factor of 100 in primary beam intensities and up to a factor of 10,000 in secondary radioactive beam intensities are key technical goals of the proposal. The second branch of the so-called Facility for Antiproton and Ion Research (FAIR) is the production of antiprotons and their storage in rings and traps. The facility will provide beam energies a factor of approximately 15 higher than presently available at the GSI for all ions, from protons to uranium. The shielding design of the synchrotron SIS 100/300 is shown exemplarily by using Monte Carlo calculations with the FLUKA code. The experimental area serving the investigation of compressed baryonic matter is analysed in the same way. In addition, a dose comparison is made for an experimental area operated with medium energy heavy-ion beams. Here, Monte Carlo calculations are performed by using either heavy-ion primary particles or proton beams with intensities scaled by the mass number of the corresponding heavy-ion beam.


Assuntos
Arquitetura de Instituições de Saúde/métodos , Método de Monte Carlo , Aceleradores de Partículas/instrumentação , Monitoramento de Radiação/métodos , Proteção Radiológica/instrumentação , Proteção Radiológica/métodos , Simulação por Computador , Desenho de Equipamento/métodos , Análise de Falha de Equipamento/métodos , Arquitetura de Instituições de Saúde/instrumentação , Alemanha , Íons Pesados , Modelos Estatísticos , Prótons , Doses de Radiação , Medição de Risco/métodos , Fatores de Risco
6.
Radiat Prot Dosimetry ; 115(1-4): 437-40, 2005.
Artigo em Inglês | MEDLINE | ID: mdl-16381762

RESUMO

The Gesellschaft für Schwerionenforschung in Darmstadt is planning a new accelerator Facility for Antiproton and Ion Research (FAIR). Two future experimental areas are regarded to be the most decisive points concerning the activation of air. One is the area for the production of antiprotons. A second crucial experimental area is the so-called Super Fragment Separator. The production of radioactive isotopes in air is calculated using the residual nuclei option of the Monte Carlo program FLUKA. The results are compared with the data for the activation of air given by Sullivan and in IAEA report 283. The resulting effective dose is calculated using a program package from the German Federal Office for Radiation Protection, the Bundesamt für Stranlenschutz. The results demonstrate that a direct emission of the total radioactivity produced into the air will probably conflict with the limits of the German Radiation Protection Ordinance. Special measures have to be planned in order to reduce the amount of radioactivity released into the air.


Assuntos
Poluentes Radioativos do Ar/análise , Ar/análise , Desenho Assistido por Computador , Meio Ambiente , Aceleradores de Partículas/instrumentação , Monitoramento de Radiação/métodos , Proteção Radiológica/métodos , Simulação por Computador , Análise de Falha de Equipamento , Arquitetura de Instituições de Saúde/métodos , Alemanha , Transferência Linear de Energia , Modelos Estatísticos , Método de Monte Carlo , Doses de Radiação , Proteção Radiológica/instrumentação , Medição de Risco/métodos , Fatores de Risco
7.
Mutat Res ; 431(2): 429-48, 1999 Dec 17.
Artigo em Inglês | MEDLINE | ID: mdl-10636006

RESUMO

Mutation induction at the Hprt locus in Chinese hamster cells was studied after exposure to ultraviolet light, X-rays and alpha particles. While mutant frequency as a function of dose or fluence followed a linear-quadratic relationship with UV and X-rays, it showed a linear dependence for alpha particles. If mutant frequency is plotted vs. the logarithm of surviving fraction, a linear relationship is found in all cases although with different slopes. These are about equal with the two types of ionising radiations but about 10 times larger for UV. They can be used as a measure of mutagenic potential and are termed mutagenicity. It is shown that this parameter is correlated with the maximum of mutant yield, i.e., the number of mutants per cell at risk. It is concluded from this analysis that the maximum mutant yield is always found at doses or fluences which lead to 37% survival irrespective of the kind of radiation. If mutation induction is measured in X-irradiated cells after pre-exposure to UV, mutant frequency is higher than expected on the basis of independent action of the two radiations. Deletion spectra were determined by using multiplex polymerase chain reaction. It was found that the background of spontaneous mutants varied considerably and showed frequently repetitive patterns, presumably because of clonal expansion of pre-formed mutants. UV-induced mutants did not contain any deletions, while those with both X-rays and alpha particles the majority displayed partial and total deletions. Based on a total number of 134 X-ray- and 192 alpha-induced mutants, it is concluded that the total fraction of mutant clones without deletions (partial or total) is about 40% for X-rays and only about 20% for alpha-particles.


Assuntos
Hipoxantina Fosforribosiltransferase/genética , Hipoxantina Fosforribosiltransferase/efeitos da radiação , Mutação/efeitos da radiação , Partículas alfa , Animais , Linhagem Celular/efeitos da radiação , Sobrevivência Celular/efeitos da radiação , Cricetinae , Cricetulus , Deleção de Sequência , Raios Ultravioleta , Raios X
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