Detalhe da pesquisa
1.
Modulation of microRNA processing by 5-lipoxygenase.
FASEB J
; 35(2): e21193, 2021 02.
Artigo
Inglês
| MEDLINE | ID: mdl-33205517
2.
Beyond leukotriene formation-The noncanonical functions of 5-lipoxygenase.
Prostaglandins Other Lipid Mediat
; 142: 24-32, 2019 06.
Artigo
Inglês
| MEDLINE | ID: mdl-30930090
3.
Characterization and cellular localization of human 5-lipoxygenase and its protein isoforms 5-LOΔ13, 5-LOΔ4 and 5-LOp12.
Biochim Biophys Acta Mol Cell Biol Lipids
; 1862(5): 561-571, 2017 May.
Artigo
Inglês
| MEDLINE | ID: mdl-28257804
4.
Characterization of the interaction of human 5-lipoxygenase with its activating protein FLAP.
Biochim Biophys Acta
; 1851(11): 1465-72, 2015 Nov.
Artigo
Inglês
| MEDLINE | ID: mdl-26327594
5.
Lipoxin and resolvin biosynthesis is dependent on 5-lipoxygenase activating protein.
FASEB J
; 29(12): 5029-43, 2015 Dec.
Artigo
Inglês
| MEDLINE | ID: mdl-26289316
6.
Phosphorylation mimicking mutations of ALOX5 orthologs of different vertebrates do not alter reaction specificities of the enzymes.
Biochim Biophys Acta
; 1842(10): 1460-6, 2014 Oct.
Artigo
Inglês
| MEDLINE | ID: mdl-25025884
7.
Stabilisation and characterisation of the isolated regulatory domain of human 5-lipoxygenase.
Biochim Biophys Acta
; 1842(10): 1538-47, 2014 Oct.
Artigo
Inglês
| MEDLINE | ID: mdl-25107828
8.
Sulfo-NHS-SS-biotin derivatization: a versatile tool for MALDI mass analysis of PTMs in lysine-rich proteins.
Proteomics
; 14(6): 659-67, 2014 Mar.
Artigo
Inglês
| MEDLINE | ID: mdl-24449390
9.
The role of human 5-Lipoxygenase (5-LO) in carcinogenesis - a question of canonical and non-canonical functions.
Oncogene
; 43(18): 1319-1327, 2024 May.
Artigo
Inglês
| MEDLINE | ID: mdl-38575760
10.
Inhibition of 5-lipoxygenase by U73122 is due to covalent binding to cysteine 416.
Biochim Biophys Acta
; 1821(2): 279-86, 2012 Feb.
Artigo
Inglês
| MEDLINE | ID: mdl-22137889
11.
Knock-out of 5-lipoxygenase in overexpressing tumor cells-consequences on gene expression and cellular function.
Cancer Gene Ther
; 30(1): 108-123, 2023 01.
Artigo
Inglês
| MEDLINE | ID: mdl-36114329
12.
Human 5-lipoxygenase regulates transcription by association to euchromatin.
Biochem Pharmacol
; 203: 115187, 2022 09.
Artigo
Inglês
| MEDLINE | ID: mdl-35878796
13.
Dimerization of human 5-lipoxygenase.
Biol Chem
; 392(12): 1097-111, 2011 Dec.
Artigo
Inglês
| MEDLINE | ID: mdl-22050225
14.
Sulindac sulfide suppresses 5-lipoxygenase at clinically relevant concentrations.
Cell Mol Life Sci
; 67(5): 797-806, 2010 Mar.
Artigo
Inglês
| MEDLINE | ID: mdl-20091083
15.
5-Lipoxygenase (ALOX5): Genetic susceptibility to type 2 diabetes and vitamin D effects on monocytes.
J Steroid Biochem Mol Biol
; 187: 52-57, 2019 03.
Artigo
Inglês
| MEDLINE | ID: mdl-30521849
16.
Iron-Dependent Trafficking of 5-Lipoxygenase and Impact on Human Macrophage Activation.
Front Immunol
; 10: 1347, 2019.
Artigo
Inglês
| MEDLINE | ID: mdl-31316498
17.
Melleolides from Honey Mushroom Inhibit 5-Lipoxygenase via Cys159.
Cell Chem Biol
; 26(1): 60-70.e4, 2019 01 17.
Artigo
Inglês
| MEDLINE | ID: mdl-30415966
18.
Drug-Mediated Intracellular Donation of Nitric Oxide Potently Inhibits 5-Lipoxygenase: A Possible Key to Future Antileukotriene Therapy.
Antioxid Redox Signal
; 28(14): 1265-1285, 2018 05 10.
Artigo
Inglês
| MEDLINE | ID: mdl-28699354
19.
Characterization of the molecular mechanism of 5-lipoxygenase inhibition by 2-aminothiazoles.
Biochem Pharmacol
; 123: 52-62, 2017 Jan 01.
Artigo
Inglês
| MEDLINE | ID: mdl-27671344
20.
Michael acceptor containing drugs are a novel class of 5-lipoxygenase inhibitor targeting the surface cysteines C416 and C418.
Biochem Pharmacol
; 125: 55-74, 2017 Feb 01.
Artigo
Inglês
| MEDLINE | ID: mdl-27823964