Detalhe da pesquisa
1.
Polygenic Prediction of Weight and Obesity Trajectories from Birth to Adulthood.
Cell
; 177(3): 587-596.e9, 2019 04 18.
Artigo
Inglês
| MEDLINE | ID: mdl-31002795
2.
Germline Mutations in CIDEB and Protection against Liver Disease.
N Engl J Med
; 387(4): 332-344, 2022 07 28.
Artigo
Inglês
| MEDLINE | ID: mdl-35939579
3.
Correction: A missense variant in Mitochondrial Amidoxime Reducing Component 1 gene and protection against liver disease.
PLoS Genet
; 17(4): e1009503, 2021 Apr.
Artigo
Inglês
| MEDLINE | ID: mdl-33822779
4.
MitoCarta3.0: an updated mitochondrial proteome now with sub-organelle localization and pathway annotations.
Nucleic Acids Res
; 49(D1): D1541-D1547, 2021 01 08.
Artigo
Inglês
| MEDLINE | ID: mdl-33174596
5.
A missense variant in Mitochondrial Amidoxime Reducing Component 1 gene and protection against liver disease.
PLoS Genet
; 16(4): e1008629, 2020 04.
Artigo
Inglês
| MEDLINE | ID: mdl-32282858
6.
Genetic Association of Albuminuria with Cardiometabolic Disease and Blood Pressure.
Am J Hum Genet
; 103(4): 461-473, 2018 10 04.
Artigo
Inglês
| MEDLINE | ID: mdl-30220432
7.
Phenotypic Refinement of Heart Failure in a National Biobank Facilitates Genetic Discovery.
Circulation
; 139(4): 489-501, 2019 Jan 22.
Artigo
Inglês
| MEDLINE | ID: mdl-30586722
8.
Insulin Dissociates the Effects of Liver X Receptor on Lipogenesis, Endoplasmic Reticulum Stress, and Inflammation.
J Biol Chem
; 291(3): 1115-22, 2016 Jan 15.
Artigo
Inglês
| MEDLINE | ID: mdl-26511317
9.
The Role of Proprotein Convertase Subtilisin/Kexin Type 9 in Nephrotic Syndrome-Associated Hypercholesterolemia.
Circulation
; 134(1): 61-72, 2016 Jul 05.
Artigo
Inglês
| MEDLINE | ID: mdl-27358438
10.
Role of Insulin in the Regulation of Proprotein Convertase Subtilisin/Kexin Type 9.
Arterioscler Thromb Vasc Biol
; 35(7): 1589-96, 2015 Jul.
Artigo
Inglês
| MEDLINE | ID: mdl-26023080
11.
Association of Habitual Alcohol Intake With Risk of Cardiovascular Disease.
JAMA Netw Open
; 5(3): e223849, 2022 03 01.
Artigo
Inglês
| MEDLINE | ID: mdl-35333364
12.
Framework From a Multidisciplinary Approach for Transitioning Variants of Unknown Significance From Clinical Genetic Testing in Kidney Disease to a Definitive Classification.
Kidney Int Rep
; 7(9): 2047-2058, 2022 Sep.
Artigo
Inglês
| MEDLINE | ID: mdl-36090499
13.
Multiancestry exome sequencing reveals INHBE mutations associated with favorable fat distribution and protection from diabetes.
Nat Commun
; 13(1): 4844, 2022 08 23.
Artigo
Inglês
| MEDLINE | ID: mdl-35999217
14.
Increased soluble urokinase plasminogen activator levels modulate monocyte function to promote atherosclerosis.
J Clin Invest
; 132(24)2022 12 15.
Artigo
Inglês
| MEDLINE | ID: mdl-36194491
15.
A multiancestry genome-wide association study of unexplained chronic ALT elevation as a proxy for nonalcoholic fatty liver disease with histological and radiological validation.
Nat Genet
; 54(6): 761-771, 2022 06.
Artigo
Inglês
| MEDLINE | ID: mdl-35654975
16.
Machine learning enables new insights into genetic contributions to liver fat accumulation.
Cell Genom
; 1(3)2021 Dec 08.
Artigo
Inglês
| MEDLINE | ID: mdl-34957434
17.
Electronic health record-based genome-wide meta-analysis provides insights on the genetic architecture of non-alcoholic fatty liver disease.
Cell Rep Med
; 2(11): 100437, 2021 11 16.
Artigo
Inglês
| MEDLINE | ID: mdl-34841290
18.
Cardiometabolic Polygenic Risk Scores and Osteoarthritis Outcomes: A Mendelian Randomization Study Using Data From the Malmö Diet and Cancer Study and the UK Biobank.
Arthritis Rheumatol
; 71(6): 925-934, 2019 06.
Artigo
Inglês
| MEDLINE | ID: mdl-30615301
19.
Genome-wide polygenic scores for common diseases identify individuals with risk equivalent to monogenic mutations.
Nat Genet
; 50(9): 1219-1224, 2018 09.
Artigo
Inglês
| MEDLINE | ID: mdl-30104762
20.
The beta secretase BACE1 regulates the expression of insulin receptor in the liver.
Nat Commun
; 9(1): 1306, 2018 04 03.
Artigo
Inglês
| MEDLINE | ID: mdl-29610518