Relay optical function and pre-construction results of a Giant Steerable Science Mirror for a thirty meter telescope.

The Giant Steerable Science Mirror (GSSM) is the tertiary mirror system of the Thirty Meter Telescope (TMT) that relays optical beams from the secondary mirror to active instruments on Nasmyth platforms. One of the key technologies involved in GSSM functions is the error budget allocation from the system engineering of TMT. A novel approach of error analysis and allocation with strong adaptability, which is based on normalized Point Source Sensitivity (PSSn), is proposed. The relay optical function including the quality of the wavefront, the rationality of the mechanism, and the stability of the light were achieved based on the proposed method. The experiments validate the proposed method.

Research overview of chemical constituents, pharmacological activity, and clinical application of Swertia patens Burk / 国际中医中药杂志

Swertia patens Burk. is a commonly used herbal medicine of the Yi nationality in Yunnan, China. It is widely used in the treatment of children with spastic abdominal pain, cholecystitis, and other diseases, mainly containing iridoid glycosides and ketone compounds. The highest and most significant pharmacological activity, with antispasmodic, analgesic, sedative, anti-inflammatory, liver-protecting, stomach-protecting, and other effects, is closely related to its effects of soothing the liver, clearing heat, and relieving stomach pain. As a very distinctive pediatric folk medicine, the related quality standards of Swertia patens Burk. have not been perfected, and the development of preparations is relatively lagging.

Clinical application of combined detection of serum Cys-C, 5'-NT and AFP in hepatocellular carcinoma / 肿瘤研究与临床

Objective To explore the clinical application of single or combined detection of serum Cys-C,5'-NT and AFP in hepatocellular carcinoma (HCC) in order to provide the platform for early diagnosis and prognosis evaluation.Methods The serum levels of Cys-C,5'-NT and AFP from 148 cases of HCC patients (HCC group),135 cases of liver cirrhosis patients (LC group) and 155 cases of hepatitis (hepatitis group) and 100 healthy people (control group) were measured by latex-enhanced immunoturbidimetric assay (LEITD),peroxidase method and electrochemiluminescence immunoassay (ECLI),respectively.Then their differences had been compared.The sensitivity,specificity and Youden's index were calculated and the results were analyzed by receiver operating characteristic (ROC) curve.Results The levels of serum Cys-C,5'-NT and AFP were significantly different in 4 groups.The differences were statistically significant (F =12.35,42.25,58.12,P =0.000).The sensitivity of three indicators for diagnosing HCC was 100 ％,which was higher than that of single or two combined detection (P ＜ 0.05),and the specificity was 78.97 ％.The area under ROC curves of combined detection of three indicators was 0.977,which was also higher than single or two combined detection (P ＜ 0.05).Conclusions The combined detection of serum Cys-C,5'-NT and AFP can greatly increase the sensitivity and accuracy for diagnosing HCC,which has an important clinical value for early diagnosis.Therefore it is worth popularizing and applying on clinic.