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1.
J Biomech Eng ; 144(3)2022 03 01.
Artigo em Inglês | MEDLINE | ID: mdl-34590691

RESUMO

The characterization of human subcutaneous adipose tissue (SAT) under high-rate loading is valuable for development of biofidelic finite element human body models (FE-HBMs) to predict seat belt-pelvis interaction and injury risk in vehicle crash simulations. While material characterization of SAT has been performed at 25 °C or 37 °C, the effect of temperature on mechanical properties of SAT under high-rate and large-deformation loading has not been investigated. Similarly, while freezing is the most common preservation technique for cadaveric specimens, the effect of freeze-thaw on the mechanical properties of SAT is also absent from the literature. Therefore, the aim of this study was to determine the effect of freezing and temperature on mechanical properties of human SAT. Fresh and previously frozen human SAT specimens were obtained and tested at 25 °C and 37 °C. High-rate indentation and puncture tests were performed, and indentation-puncture force-depth responses were obtained. While the chance of material failure was found to be different between temperatures and between fresh and previously frozen tissue, statistical analyses revealed that temperature and freezing did not change the shear modulus and failure characteristics of SAT. Therefore, the results of the current study indicated that SAT material properties characterized from either fresh or frozen tissue at either 25 °C or 37 °C could be used for enhancing the biofidelity of FE-HBMs.


Assuntos
Tecido Adiposo , Punções , Fenômenos Biomecânicos , Congelamento , Humanos , Temperatura
2.
Hum Factors ; 58(2): 261-78, 2016 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-26459426

RESUMO

BACKGROUND: Previously published statistical models of driving posture have been effective for vehicle design but have not taken into account the effects of age. OBJECTIVE: The present study developed new statistical models for predicting driving posture. METHODS: Driving postures of 90 U.S. drivers with a wide range of age and body size were measured in laboratory mockup in nine package conditions. Posture-prediction models for female and male drivers were separately developed by employing a stepwise regression technique using age, body dimensions, vehicle package conditions, and two-way interactions, among other variables. RESULTS: Driving posture was significantly associated with age, and the effects of other variables depended on age. A set of posture-prediction models is presented for women and men. The results are compared with a previously developed model. CONCLUSION: The present study is the first study of driver posture to include a large cohort of older drivers and the first to report a significant effect of age. APPLICATION: The posture-prediction models can be used to position computational human models or crash-test dummies for vehicle design and assessment.


Assuntos
Condução de Veículo , Quadril/fisiologia , Modelos Estatísticos , Postura/fisiologia , Adulto , Idoso , Idoso de 80 Anos ou mais , Envelhecimento/fisiologia , Pontos de Referência Anatômicos/fisiologia , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Adulto Jovem
3.
Ergonomics ; 59(6): 796-805, 2016 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-26328769

RESUMO

Few statistical models of rear seat passenger posture have been published, and none has taken into account the effects of occupant age. This study developed new statistical models for predicting passenger postures in the rear seats of automobiles. Postures of 89 adults with a wide range of age and body size were measured in a laboratory mock-up in seven seat configurations. Posture-prediction models for female and male passengers were separately developed by stepwise regression using age, body dimensions, seat configurations and two-way interactions as potential predictors. Passenger posture was significantly associated with age and the effects of other two-way interaction variables depended on age. A set of posture-prediction models are presented for women and men, and the prediction results are compared with previously published models. This study is the first study of passenger posture to include a large cohort of older passengers and the first to report a significant effect of age for adults. The presented models can be used to position computational and physical human models for vehicle design and assessment. Practitioner Summary: The significant effects of age, body dimensions and seat configuration on rear seat passenger posture were identified. The models can be used to accurately position computational human models or crash test dummies for older passengers in known rear seat configurations.


Assuntos
Automóveis , Modelos Estatísticos , Postura , Adulto , Fatores Etários , Idoso , Idoso de 80 Anos ou mais , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Modelos Teóricos , Análise de Regressão , Fatores Sexuais , Adulto Jovem
4.
Stapp Car Crash J ; 68: 1-13, 2024 Aug 27.
Artigo em Inglês | MEDLINE | ID: mdl-39250775

RESUMO

The increased use of computational human models in evaluation of safety systems demands greater attention to selected methods in coupling the model to its seated environment. This study assessed the THUMS v4.0.1 in an upright driver posture and a reclined occupant posture. Each posture was gravity settled into an NCAC vehicle model to assess model quality and HBM to seat coupling. HBM to seat contact friction and seat stiffness were varied across a range of potential inputs to evaluate over a range of potential inputs. Gravity settling was also performed with and without constraints on the pelvis to move towards the target H-Point. These combinations resulted in 18 simulations per posture, run for 800 ms. In addition, 5 crash pulse simulations (51.5 km/h delta V) were run to assess the effect of settling time on driver kinematics. HBM mesh quality and HBM to seat coupling metrics were compared at kinetically identical time points during the simulation to an end state where kinetic energy was near zero. A gravity settling time of 350 ms was found to be optimal for the upright driver posture and 290 ms for the reclined occupant posture. This suggests that reclined passengers can be settled for less time than upright passengers, potentially due to the increased contact area. The pelvis constrained approach was recommended for the upright driver posture and was not recommended for the reclined occupant posture. The recommended times were sufficient to gravity settle both postures to match the quality metrics of the 800 ms gravity settled time. Driver kinematics were found to be vary with gravity settling time. Future work will include verifying that these recommendations hold for different HBMs and test modes.

5.
Biomolecules ; 14(9)2024 Sep 20.
Artigo em Inglês | MEDLINE | ID: mdl-39334948

RESUMO

The primary pre-neoplastic lesion of the lower esophagus in the vicinity of the gastroesophageal junction (GEJ) is any Barrett's esophageal lesions (BE), and esophageal neoplasia has increased in the US population with predispositions (Caucasian males, truncal obesity, age, and GERD). The responses to BE are endoscopic and screening cytologic programs with endoscopic ablation of various forms. The former have not been proven to be cost-effective and there are mixed results for eradication. A fresh approach is sorely needed. We prospectively followed 2229 mostly male veterans at high risk for colorectal cancer in a 27-year longitudinal long-term study, collecting data on colorectal neoplasia development and other preneoplastic lesions, including BE and spontaneous regression (SR). Another cross-sectional BE study at a similar time period investigated antigenic changes at the GEJ in both BE glandular and squamous mucosa immunohistochemistry and the role of inflammation. Ten of the prospective cohort (21.7%) experienced SR out of a total of forty-six BE patients. Significant differences between SR and stable BE were younger age (p < 0.007); lower platelet levels (p < 0.02); rectal p87 elevation in SR (p < 0.049); a reduced innate immune system (InImS) FEREFF ratio (ferritin: p87 colonic washings) (p < 0.04). Ancillary testing showed a broad range of neoplasia biomarkers. InImS markers may be susceptible to intervention using commonplace and safe medical interventions and encourage SR.


Assuntos
Esôfago de Barrett , Neoplasias Esofágicas , Humanos , Masculino , Pessoa de Meia-Idade , Esôfago de Barrett/patologia , Esôfago de Barrett/metabolismo , Neoplasias Colorretais/patologia , Neoplasias Colorretais/metabolismo , Neoplasias Esofágicas/patologia , Neoplasias Esofágicas/metabolismo
6.
Ann Biomed Eng ; 51(11): 2566-2578, 2023 Nov.
Artigo em Inglês | MEDLINE | ID: mdl-37442922

RESUMO

The interaction of the three-point seat belt with the occupant, particularly the lap belt with the pelvis, is affected by a multitude of intrinsic and extrinsic factors, including the torso recline angle, lap belt angle, and occupant body mass index (BMI). While field data analyses have shown the strong safety benefit for seat belt use regardless of occupant size or crash direction, the term "submarining" historically has been used to describe a scenario in which the lap belt loads the abdominal soft tissue and organs, superior and posterior to the pelvic bone. While contemporary restraint systems work to effectively address the risk of submarining in occupants properly seated and properly belted, scenarios in which the lap belt may not properly engage the load-bearing pelvis remain. These scenarios, including a reclined torso angle or shallow lap belt angle, require further study. In this research study, eight non-injurious seated belt pull tests were conducted on two constrained whole-body cadavers of above-normal BMI (≥ 25 kg/m2) with controlled variation of torso and lap belt-pelvis angles. Test factors affecting belt engagement with the pelvis were identified for each subject. Belt engagement was largely affected by the initial placement of the lap belt. The initial belt placement was affected by the torso angle which influenced the distribution of the abdominal soft tissue. The belt disengagement thresholds differed between subjects due to the inter-subject differences in soft tissue distribution, which affected the lap belt kinematics relative to the pelvis. In addition to improving the understanding of this particular submarining mechanism, this study provides a dataset for future validation of human body model soft tissue deformation response from lap belt loading.

7.
Traffic Inj Prev ; 24(sup1): S55-S61, 2023.
Artigo em Inglês | MEDLINE | ID: mdl-37267016

RESUMO

OBJECTIVE: The goal of this study was to evaluate the effect of axial compression, employed with a follower-load mechanism, on the response of the lumbar spine in flexion and extension bending. Additional goals include measurement of both the kinetic (stiffness) and kinematic (deformation distribution) responses, evaluating how the responses vary across specimens, and to develop response corridors that can be used to evaluate human body models (HBMs) and anthropomorphic test devices (ATDs). METHODS: Seven mid-sized male adult lumbar spines (T12-S1) from postmortem human surrogates were tested in subinjurious flexion and extension bending with 0, 900, and 1800 N of superimposed axial compression. Tests were performed in load-control with a 6-DOF robotic test system that applied pure flexion and extension moments to the specimens, and axial compression was directed along the spine's curvature via a follower load mechanism powered by force-controlled linear actuators. Load-deformation response data were captured and used to characterize the kinetic response of the lumbar spine in flexion/extension, and how it varies with axial compression. Individual vertebral kinematics were captured using 3D motion capture and the data was used to illustrate the distribution of bending deformation across each intervertebral joint of the spine, as well has how that distribution changes with axial compression. These response data were used to develop elliptical path-length parameterized response corridors for surrogate biofidelity evaluation. RESULTS: The lumbar spine was found to be generally stiffer in extension than in flexion, but this difference decreased with increasing axial compression. The lumbar spine exhibited a nonlinear kinetic (moment vs. angle) response in flexion that became more linear and stiffer with the addition of axial compression. In flexion without axial load, the majority of the bending deformation occurred at the L5-S1 joint, whereas in extension, deformation was more evenly distributed across the different intervertebral levels, but the locus of deformation was located in the mid-proximal lumbar at L2-L3. CONCLUSIONS: The superposition of axial compression in the lumbar spine affects the kinetic and kinematic response of the lumbar spine in flexion and extension. The response data and approach detailed in this study permit better assessment of ATD and HBM biofidelity.


Assuntos
Acidentes de Trânsito , Vértebras Lombares , Adulto , Humanos , Masculino , Vértebras Lombares/fisiologia , Amplitude de Movimento Articular/fisiologia , Fenômenos Biomecânicos/fisiologia , Autopsia
8.
Ann Biomed Eng ; 51(6): 1216-1225, 2023 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-36681746

RESUMO

Anticipating changes to vehicle interiors with future automated driving systems, the automobile industry recently has focused attention on crash response in novel postures with increased seatback recline. Prior research found that this posture may result in greater risk of lumbar spine injury in the event of a frontal crash. This study developed a lumbar spine injury risk function (IRF) that estimated injury risk as a function of simultaneously applied compression force and flexion moment. Force and moment failure data from 40 compression-flexion tests were utilized in a Weibull survival model, including appropriate data censoring. A mechanics-based injury metric was formulated, where lumbar spine compression force and flexion moment were normalized by specimen geometry. Subject age was incorporated as a covariate to further improve model fit. A weighting factor was included to adjust the influence of force and moment, and parameter optimization yielded a value of 0.11. Thus, the normalized compression force component had a greater effect on injury risk than the normalized flexion moment component. Additionally, as force was nominally increased, less moment was required to produce injury for a given age and specimen geometry. The resulting IRF may be utilized to improve occupant safety in the future.


Assuntos
Acidentes de Trânsito , Traumatismos da Coluna Vertebral , Humanos , Automóveis , Vértebras Lombares/fisiologia , Fenômenos Biomecânicos
9.
Curr Oncol ; 30(9): 7950-7963, 2023 08 29.
Artigo em Inglês | MEDLINE | ID: mdl-37754493

RESUMO

BACKGROUND: We evaluated the phenotype of sporadic gastric cancer based on HP status and binding of a tumor risk marker monoclonal, Adnab-9. METHODS: We compared a familial GC kindred with an extremely aggressive phenotype to HP-positive (HP+) and -negative (HP-) sporadic gastric adenocarcinoma (GC) patients in the same community to determine if similar phenotypes exist. This might facilitate gene discovery to understand the pathogenesis of aggressive GC phenotypes, particularly with publications implicating immune-related gene-based signatures, and the development of techniques to gauge the stance of the innate immune system (InImS), such as the FERAD ratio (blood ferritin:fecal Adnab-9 binding OD-background binding). Resection specimens for the sporadic and familial group were stained for HP and examined for intestinal metaplasia (IM) and immunostaining for Adnab-9. Familial kindred specimens were also tested for the E-cadherin mutation and APC (adenomatous polyposis coli). Survival was evaluated. RESULTS: Of 40 GC patients, 25% were HP+ with a greater proportion of intestinal metaplasia (IM) and gastric atrophy than the HP- group. The proband of the familial GC kindred, a 32-year-old mother with fatal GC, was survived by 13-year-old identical twins. Twin #1 was HP- with IM and Twin #2 was HP+. Both twins subsequently died of GC within two years. The twins did not have APC or E-cadherin mutations. The mean overall survival in the HP+ sporadic GC group was 2.47 ± 2.58 years and was 0.57 ± 0.60 years in the HP- group (p = 0.01). Survival in the kindred was 0.22 ± 0.24 years. Adnab-9 labeling was positive in fixed tissues of 50% of non-familial GC patients and in gastric tissue extract from Twin #2. The FERAD ratio was determined separately in six prospectively followed patient groups (n = 458) and was significantly lower in the gastric cancer patients (n = 10) and patients with stomach conditions predisposing them to GC (n = 214), compared to controls (n = 234 patients at increased risk for colorectal cancer but without cancer), suggesting a failure of the InImS. CONCLUSION: The HP+ sporadic GC group appears to proceed through a sequence of HP infection, IM and atrophy before cancer supervenes, and the HP- phenotype appear to omit this sequence. The familial cases may represent a subset with both features, but the natural history strongly resembles that of the HP- group. Two different paths of carcinogenesis may exist locally for sporadic GC. The InImS may also be implicated in prognosis. Identifying these patients will allow for treatment stratification and early diagnosis to improve GC survival.


Assuntos
Adenocarcinoma , Helicobacter pylori , Neoplasias Gástricas , Humanos , Adulto , Adolescente , Neoplasias Gástricas/genética , Adenocarcinoma/genética , Carcinogênese , Atrofia , Caderinas
10.
Traffic Inj Prev ; 23(sup1): S20-S25, 2022.
Artigo em Inglês | MEDLINE | ID: mdl-35704679

RESUMO

OBJECTIVE: The objective of the current study was to increase scientific understanding of rear-seat passenger seating position, postures, CRS use, and belt use through a naturalistic study. A secondary objective was to compare data from vehicles used in ride-hailing with data from other vehicles. METHOD: Video cameras were installed in the passenger cabins of the vehicles of 75 drivers near the center of the windshield. The video data were downloaded after the vehicles were operated by their owners for two weeks. Video frames were sampled from near the ends and in the middle of each trip, and at five-minute intervals in trips longer than 15 min. A total of 7,323 frames with second-row passengers were manually coded. RESULTS: A total of 444 unique second-row passengers were identified in video frames from 1,188 trips taken in 65 of the 75 vehicles in the study. Two of the vehicles that were driven for commercial ride-hailing during the study period accounted for 199 (45%) of the passengers. Considering multiple passengers in some trips, a total of 1,899 passenger-trips were identified. For passengers not using child restraint systems (CRS), the belt use rate was 65% in the non-ride-hailing vehicles versus 32% among passengers in the ride-hailing vehicles. No CRS use was observed in the ride-hailing vehicles. Among children using backless boosters, the shoulder belt was lateral to the clavicle or under the arm in 26% of frames. Among belted passengers not using CRS, the belt was lateral to the clavicle or on the neck about 6% of the time. Belted passengers not using CRS were observed leaning to the left or right about 27% of the time, with leaning away from the shoulder belt more common than leaning into the belt. CONCLUSIONS: This study is the first to report seating position, posture, and belt fit observations for a large naturalistic sample of second-row passengers that includes adult occupants. The data suggest that low rear seat belt use rates remain a concern, particularly in ride-hailing vehicles. Non-nominal belt placement and posture may also be common in second-row seating positions.


Assuntos
Acidentes de Trânsito , Sistemas de Proteção para Crianças , Criança , Adulto , Humanos , Cintos de Segurança , Postura
11.
J Biomech ; 135: 111051, 2022 04.
Artigo em Inglês | MEDLINE | ID: mdl-35325753

RESUMO

Vehicle safety systems have substantially decreased motor vehicle crash-related injuries and fatalities, but injuries to the lumbar spine still have been reported. Experimental and computational analyses of upright and, particularly, reclined occupants in frontal crashes have shown that the lumbar spine can be subjected to simultaneous and out-of-phase combined axial compression and flexion loading. Lumbar spine failure tolerance in combined compression-flexion has not been widely explored in the literature. Therefore, the goal of this study was to measure the failure tolerance of the lumbar spine in combined compression and flexion. Forty lumbar spine segments with three vertebrae (one unconstrained) and two intervertebral discs (both unconstrained) were pre-loaded with axial compression (2200N, 3300N, or 4500N) and then subjected to rotation-controlled dynamic flexion bending until failure. Clinically relevant middle vertebra fractures were observed in twenty-one of the specimens, including compression and burst fractures. The remaining nineteen specimens experienced failure at the potting-grip interface. Failure tolerance varied within the sample and were categorized by the appropriate data censoring, with clinically relevant middle vertebrae fractures characterized as uncensored or left-censored and potting-grip fractures characterized as right-censored. Average failure force and moment were 3290N (range: 1580N to 5042N) and 51Nm (range: 0Nm to 156 Nm) for uncensored data, 3686N (range: 3145N to 4112N) and 0Nm for left-censored data, and 3470N (range: 2138N to 5062N) and 101Nm (range: 27Nm to 182Nm) for right-censored data. These data can be used to develop and improve injury prediction tools for lumbar spine fractures and further research in future safety systems.


Assuntos
Vértebras Lombares , Fraturas da Coluna Vertebral , Acidentes de Trânsito , Fenômenos Biomecânicos , Humanos , Amplitude de Movimento Articular
12.
J Manipulative Physiol Ther ; 34(5): 290-6, 2011 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-21640252

RESUMO

PURPOSE: Chiropractic manipulation of the thoracic spine may induce chest deformations in the anterior-posterior direction. Yet, few studies have examined the biomechanical response of the chest associated with these manipulations. Consequently, an experimental analysis was undertaken to quantify chest compressions resulting from chiropractic thoracic spine manipulations and to estimate amount of risk for injury. METHODS: A 2-part study approach was used with a Hybrid III anthropomorphic test dummy. In part 1, the dummy was positioned prone on a chiropractic table and subjected to thoracic spine manipulation by 2 experienced doctors of chiropractic. Chest compressions were quantified in the anterior-posterior direction. Manipulation forces were self-selected, with "typical" and "maximum" efforts examined. In part 2, the dummy was positioned beneath a force-instrumented mechanical piston device. Using the piston, chest compressions were induced with magnitudes identical to those recorded during chiropractic manipulation as well as magnitudes sufficient to induce injury. In all trials, force measurements were recorded. RESULTS: Thoracic manipulations incorporating the typical and maximum efforts by the chiropractors resulted in maximum chest compressions attaining 1.8% and 4.5% of total chest depth, respectively. According to previously developed correlations between chest compression and injury severity defined using the Abbreviated Injury Scale (AIS), maximum chest compression measured during this study was only 22.7% of the compression required for greater than 10% risk of an AIS 1 injury. Abbreviated Injury Scale 1 level injuries are graded as minor severity and correspond to sternum contusion or fracture of a single rib. CONCLUSIONS: Results from this preliminary study showed that maximum chest compression during thoracic spine manipulation corresponded to minimal risk of AIS 1 level injuries.


Assuntos
Manequins , Manipulação Quiroprática/efeitos adversos , Traumatismos Torácicos/etiologia , Vértebras Torácicas , Tórax/fisiopatologia , Fenômenos Biomecânicos , Contusões/etiologia , Contusões/fisiopatologia , Fraturas Ósseas/etiologia , Fraturas Ósseas/fisiopatologia , Humanos , Escala de Gravidade do Ferimento , Funções Verossimilhança , Costelas/lesões , Medição de Risco , Esterno/lesões
13.
Acta Biomater ; 129: 188-198, 2021 07 15.
Artigo em Inglês | MEDLINE | ID: mdl-34048975

RESUMO

The mechanical behavior of subcutaneous adipose tissue (SAT) affects the interaction between vehicle occupants and restraint systems in motor vehicle crashes (MVCs). To enhance future restraints, injury countermeasures, and other vehicle safety systems, computational simulations are often used to augment experiments because of their relative efficiency for parametric analysis. How well finite element human body models (FE-HBMs), which are often used in such simulations, predict human response has been limited by the absence of material models for human SAT that are applicable to the MVC environment. In this study, for the first time, dynamic multidirectional unconfined compression and simple shear loading tests were performed on human abdominal SAT specimens under conditions similar to MVCs. We also performed multiple ramp-hold tests to evaluate the quasilinear viscoelasticity (QLV) assumption and capture the stress relaxation behavior under both compression and shear. Our mechanical characterization was supplemented with scanning electron microscopy (SEM) performed in different orientations to investigate whether the macrostructural response can be related to the underlying microstructure. While the overall structure was shown to be visually different in different anatomical planes, a preferred orientation of any fibrous structures could not be identified. We showed that the nonlinear, viscoelastic, and direction-dependent responses under compression and shear tests could be captured by incorporating QLV in an Ogden-type hyperelastic model. Our comprehensive approach will lead to more accurate computational simulations and support the collective effort on the research of future occupant protection systems. STATEMENT OF SIGNIFICANCE: There is an urgent need to characterize the mechanical behavior of human adipose tissue under multiple dynamic loading conditions, and to identify constitutive models that are able to capture the tissue response under these conditions. We performed the first series of experiments on human adipose tissue specimens to characterize the multi-directional compression and shear behavior at impact loading rates and obtained scanning electron microscope images to investigate whether the macrostructural response can be related to the underlying microstructure. The results showed that human adipose tissue is nonlinear, viscoelastic and direction dependent, and its mechanical response under compression and shear tests at different loading rates can be captured by incorporating quasi-linear viscoelasticity in an Ogden-type hyperelastic model.


Assuntos
Tecido Adiposo , Modelos Biológicos , Elasticidade , Análise de Elementos Finitos , Humanos , Pressão , Estresse Mecânico , Viscosidade
14.
Traffic Inj Prev ; 22(sup1): S116-S121, 2021.
Artigo em Inglês | MEDLINE | ID: mdl-34605723

RESUMO

OBJECTIVE: Identifying current occupant travel patterns can inform decision making regarding the design, regulation, and occupant protection systems helpful for automated vehicle systems and mobility services. METHODS: Two travel data sets were analyzed to quantify travel patterns: the 2017 National Household Travel Survey (NHTS), which provides data on household trips logged for a 24-h period, and the 2011-2015 National Automotive Sampling System-General Estimates System (NASS-GES), which contains data sampled from police-reported crashes. Analysis identified trends with driver age and gender, occupant age and gender, time of day, day of week, trip purpose, trip duration, vehicle type, as well as occupant role as solo driver, driver of others, single passenger, or multiple passengers. RESULTS: In NHTS, the median trip duration is 15 min; only 10% of trips last longer than 40 min. Trip duration does not vary with occupant role or vehicle type. Variations with trip time of day and day of week show a unimodal pattern for weekends, as well as weekday trips for those aged 55 years and older and non-solo occupants aged 18 to 29 years. Other occupant groups have a bimodal weekday travel pattern with peak trips corresponding to morning and evening rush hours.In GES, approximately half of occupants are solo drivers. Female drivers aged 55 and older travel alone 60% of the time, and drivers under age 18 and female drivers aged 30 to 54 drive alone on less than 45% of trips. Approximately 13% of occupants are single passengers, and 16% travel with a driver and at least 1 other passenger. About 16% of occupants are front seat passengers. CONCLUSIONS: This analysis of vehicle occupancy provides insights on what ridership of future automated vehicles and expanded ride-hailing services may look like. Because half of occupants are solo drivers, only 16% are multiple passengers, and median trip length is just 15 min, proposed alternative seating arrangements intended to promote comfort and passenger interaction may not represent the typical future vehicle use case in the United States. Knowledge of current occupancy patterns can help automated vehicle designers and regulators develop safe seating scenarios that meet customer needs.


Assuntos
Acidentes de Trânsito , Veículos Autônomos , Adolescente , Adulto , Feminino , Humanos , Pessoa de Meia-Idade , Polícia , Viagem , Estados Unidos , Adulto Jovem
15.
J Mech Behav Biomed Mater ; 113: 104112, 2021 01.
Artigo em Inglês | MEDLINE | ID: mdl-33010697

RESUMO

Understanding the mechanical properties of human adipose tissue, and its influence on seat belt-pelvis interaction is beneficial for computational human body models that are developed for injury prediction in the vehicle crashworthiness simulations. While various studies have characterized adipose tissue, most of the studies used porcine adipose tissue as a surrogate, and none of the studies were performed at loading rates relevant for motor vehicle collisions. In this work, the mechanical response of human and porcine adipose tissue was studied. Two dynamic loading modes (compression and simple shear) were tested in adipose tissue extracted from the human abdomen and porcine back. An Ogden hyperelastic model was used to fit the loading response, and specific material parameters were obtained for each specimen. Two-sample t-tests were performed to compare the effective shear moduli and peak stresses from porcine and human samples. The material response of the human adipose tissue was consistent with previous studies. Porcine adipose tissue was found to be significantly stiffer than human adipose tissue under compression and shear loading. Also, when material model parameters were fit to only one loading mode, the predicted response in the other mode showed a poor fit.


Assuntos
Tecido Adiposo , Animais , Elasticidade , Humanos , Projetos Piloto , Pressão , Estresse Mecânico , Suínos
16.
Traffic Inj Prev ; 21(sup1): S171-S173, 2020 10 12.
Artigo em Inglês | MEDLINE | ID: mdl-33155861

RESUMO

OBJECTIVE: The objective of this study was to investigate the use of public video from internet user-generated content as a means of collecting naturalistic driving data. METHODS: A convenience sample of 38 videos comprised of 203 events was extracted from publicly available channels on the YouTube™ platform. Each event was manually reviewed and pseudo-coded according to a subset of current CRSS variables. Pre-crash scenarios were coded using categories developed for prior NHTSA analysis. RESULTS: Crashes represented 67% of the reviewed cases. Collisions with motor vehicles accounted for 84% of all crashes in the sample. Pre-crash scenarios were able to be determined for all crashes and near-crashes. The most prevalent pre-crash scenario types in the video data were Crossing Paths (41%), Rear End (21%), and Lane Change (17%). The top pre-crash scenarios from Swanson et al., were Rear End (31%), Crossing Paths (21%), and Lane Change (12%). The most prevalent pre-near crash scenario types in the video data were Crossing Paths (32%), Lane Change (30%), and Pedestrian (12%). CONCLUSIONS: The most prevalent pre-crash scenarios in the video data were similar to those in data from FARS and NASS-GES. Though not nationally representative, this preliminary study demonstrated that user-generated content may be useful as a source of inexpensive naturalistic data and provides sufficient detail to capture important pre-crash, near-crash and crash information.


Assuntos
Acidentes de Trânsito/estatística & dados numéricos , Condução de Veículo/estatística & dados numéricos , Coleta de Dados/métodos , Gravação de Videoteipe , Humanos
17.
Traffic Inj Prev ; 21(sup1): S7-S12, 2020 10 12.
Artigo em Inglês | MEDLINE | ID: mdl-32692249

RESUMO

OBJECTIVE: Recent studies have suggested that a relationship exists between crash injury risk and occupant posture, particularly in postures different from those used with anthropomorphic test devices (ATDs) in crash testing. The objective of this study was to increase scientific understanding of typical front-seat passenger postures through a naturalistic study. METHOD: Video cameras were installed in the passenger cabins of the vehicles of 75 drivers. Reflective targets were attached to the seats and the seat position and seat back angle was moved through their available ranges during instrumentation. The video data, along with vehicle acceleration and location data, were downloaded after the vehicles were operated as usual by their owners for two weeks. Video frames were manually coded to identify characteristics of front-seat passenger posture and position. Seat position and seat back angle were estimated using the calibration data obtained during vehicle instrumentation. RESULTS: Video frames from a total of 2733 trips were coded for 306 unique front-seat passengers. For these trips, a total of 13638 frames were coded; each frame represents about four minutes of travel time. The head was rotated left or right in 33% of frames, and the torso was rotated left or right about 10% of the time and pitched forward in almost 10% of frames. No seat position or seat back angle change was noted in 40 (53%) of vehicles and the distributions of seat position and seat back angle on arrival were essentially unchanged during travel. The seat was positioned full-rear on the seat track about 23% of the time and rearward of the mid-track position in 92% of frames. The mean seat back angle was 25.4 degrees (standard deviation 6.4 degrees); seat back angle was greater than 30 degrees in 15% of frames and greater than 35 degrees in less than 1% of frames. CONCLUSIONS: This study is the first to report distributions of postures, seat positions, and seat back angles for front-seat passengers. Seat positions rearward of the middle of the seat adjustment range are common, but highly reclined postures are infrequent. Non-nominal torso and head postures also are nontrivial.


Assuntos
Condução de Veículo/estatística & dados numéricos , Postura , Postura Sentada , Cabeça/fisiologia , Humanos , Prevalência , Rotação , Tronco/fisiologia , Gravação de Videoteipe
18.
Traffic Inj Prev ; 21(1): 98-101, 2020.
Artigo em Inglês | MEDLINE | ID: mdl-31999486

RESUMO

Objective: The Hybrid-III anthropometric test devices (ATDs) are widely used by the automotive industry to evaluate restraint system performance in standardized vehicle crash tests. The relationship between the belt fit measured for people in driving posture and the belt fit obtained with ATDs has not been reported in the literature. The present study compares lap and shoulder belt fit data from ATDs and to a statistical estimate for drivers using age, stature, and BMI.Methods: The lap and shoulder belt fits were measured for small-female and midsize-male Hybrid-III ATDs in a laboratory mockup of a midsize sedan. A range of lower and upper belt anchorage locations were used. The ATD belt fit data were compared with predictions from a regression model developed by data from 97 men and women measured in the same driving package conditions. Humans were free to position the belt comfortably, even if the position was not optimal.Results: The measurements of the ATD belt fit were obtained and compared to the regression estimate for a driver using age, stature, and BMI as predictors. For the small female, the ATD's lap belt was placed 46 mm further forward and 12 mm lower relative to the pelvis than the regression model estimates for a driver's lap belt placement. For the midsize male, the lap portion of the belt was placed 13 mm more rearward and 33 mm lower on the physical ATD than the regression model estimates for a similarly sized driver. The shoulder belt was placed an average of 66 mm more inboard and 11 mm more outboard on the small-female and midsize-male physical ATDs, respectively, compared with regression model estimates for drivers.Conclusions: Differences in the lap and shoulder belt fits were quantified between the physical ATDs and regression predictions for similarly sized humans in driving postures. The consequences of these differences should be investigated to help increase understanding of the relationship between belt fit and belt performance.


Assuntos
Condução de Veículo , Postura , Cintos de Segurança/estatística & dados numéricos , Desenho de Equipamento , Feminino , Humanos , Masculino , Manequins
19.
Artigo em Inglês | MEDLINE | ID: mdl-32178285

RESUMO

BACKGROUND: With active safety and automated vehicle features becoming more available, unanticipated pre-crash vehicle maneuvers, such as evasive swerving, may become more common, and they may influence the resulting effectiveness of occupant restraints, and consequently may affect injury risks associated with crashes. Therefore, the objective of this study was to quantify the influence of age on key occupant kinematic, kinetic, and muscular responses during evasive swerving in on-road testing. METHODS: Seat belt-restrained children (10-12 years old), teens (13-17 years old), and adults (21-33 years old) experienced two evasive swerving maneuvers in a recent model sedan on a test track. Kinematics, muscle activity, and seat belt load distribution were determined and analyzed. RESULTS: Compared to teens and adults, children showed greater head and trunk motion (p < 0.03), but similar muscle activation in the into-the-belt direction of swerving. In the out-of-the-belt direction, children showed head and trunk motion more similar to teens and adults (p < 0.02), but with greater muscle activation. CONCLUSIONS: Children showed different neuromuscular control of head and trunk motion compared to older occupants. This study highlights differences in the relationship between kinematics and muscle activation across age groups, and provides new validation data for active human body models across the age range.


Assuntos
Acidentes de Trânsito , Movimento (Física) , Cintos de Segurança , Adolescente , Adulto , Fatores Etários , Fenômenos Biomecânicos , Criança , Cabeça , Humanos , Músculos , Adulto Jovem
20.
Traffic Inj Prev ; 20(sup1): S106-S111, 2019.
Artigo em Inglês | MEDLINE | ID: mdl-31381438

RESUMO

Objective: Emergency braking can potentially generate precrash occupant motion that may influence the effectiveness of restraints in the subsequent crash, particularly for rear-seated occupants who may be less aware of the impending crash. With the advent of automated emergency braking (AEB), the mechanism by which braking is achieved is changing, potentially altering precrash occupant motion. Further, due to anatomical and biomechanical differences across ages, kinematic differences between AEB and manual emergency braking (MEB) may vary between child and adult occupants. Therefore, the objective of this study was to quantify differences in rear-seated adult and pediatric kinematics and muscle activity during AEB and MEB scenarios. Methods: Vehicle maneuvers were performed in a recent model year sedan traveling at 50 km/h. MEB (acceleration ∼1 g) was achieved by the driver pressing the brake pedal with maximum effort. AEB (acceleration ∼0.8 g) was triggered by the vehicle system. Inertial and Global Positioning System data were collected. Seventeen male participants aged 10-33 were restrained in the rear right passenger seat and experienced each maneuver twice. The subjects' kinematics were recorded with an 8-camera 3D motion capture system. Electromyography (EMG) recorded muscle activity. Head and trunk displacements, raw and normalized by seated height, and peak head and trunk velocity were compared across age and between maneuvers. Mean EMG was calculated to interpret kinematic findings. Results: Head and trunk displacement and peak velocity were greater in MEB than in AEB in both raw and normalized data (P ≤ .01). No effect of age was observed (P ≥ .21). Peak head and trunk velocities were greater in repetition 1 than in repetition 2 (P ≤ .006) in MEB but not in AEB. Sternocleidomastoid (SCM) mean EMG was greater in MEB compared to AEB, and muscle activity increased in repetition 2 in MEB. Conclusions: Across all ages, head and trunk excursions were greater in MEB than AEB, despite increased muscle activity in MEB. This observation may suggest an ineffective attempt to brace the head or a startle reflex. The increased excursion in MEB compared to AEB may be attributed to differences in the acceleration pulses between the 2 scenarios. These results suggest that AEB systems can use specific deceleration profiles that have potential to reduce occupant motion across diverse age groups compared to sudden maximum emergency braking applied manually.


Assuntos
Acidentes de Trânsito/estatística & dados numéricos , Desaceleração , Cabeça/fisiologia , Equipamentos de Proteção/estatística & dados numéricos , Tronco/fisiologia , Acidentes de Trânsito/prevenção & controle , Adolescente , Adulto , Automação/estatística & dados numéricos , Fenômenos Biomecânicos , Criança , Emergências , Humanos , Masculino , Adulto Jovem
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