Detalhe da pesquisa
1.
Pharmacokinetic Interactions between the Hepatitis C Virus Inhibitors Elbasvir and Grazoprevir and HIV Protease Inhibitors Ritonavir, Atazanavir, Lopinavir, and Darunavir in Healthy Volunteers.
Antimicrob Agents Chemother
; 63(4)2019 04.
Artigo
Inglês
| MEDLINE | ID: mdl-30745392
2.
The Port Delivery System with Ranibizumab for Neovascular Age-Related Macular Degeneration: Results from the Randomized Phase 2 Ladder Clinical Trial.
Ophthalmology
; 126(8): 1141-1154, 2019 08.
Artigo
Inglês
| MEDLINE | ID: mdl-30946888
3.
Pharmacokinetics and Exposure-Response Analysis of RG7667, a Combination of Two Anticytomegalovirus Monoclonal Antibodies, in a Phase 2a Randomized Trial To Prevent Cytomegalovirus Infection in High-Risk Kidney Transplant Recipients.
Antimicrob Agents Chemother
; 62(2)2018 02.
Artigo
Inglês
| MEDLINE | ID: mdl-29133549
4.
Pharmacokinetics of sugammadex in subjects with moderate and severe renal impairmentâ©.
Int J Clin Pharmacol Ther
; 55(9): 746-752, 2017 Sep.
Artigo
Inglês
| MEDLINE | ID: mdl-28679468
5.
SYSTEMIC PHARMACOKINETICS AND PHARMACODYNAMICS OF INTRAVITREAL AFLIBERCEPT, BEVACIZUMAB, AND RANIBIZUMAB.
Retina
; 37(10): 1847-1858, 2017 Oct.
Artigo
Inglês
| MEDLINE | ID: mdl-28106709
6.
A mechanistic pharmacokinetic/pharmacodynamic model of factor D inhibition in cynomolgus monkeys by lampalizumab for the treatment of geographic atrophy.
J Pharmacol Exp Ther
; 355(2): 288-96, 2015 Nov.
Artigo
Inglês
| MEDLINE | ID: mdl-26359312
7.
Clinical Pharmacology of the Antibody-Drug Conjugate Enfortumab Vedotin in Advanced Urothelial Carcinoma and Other Malignant Solid Tumors.
Clin Pharmacokinet
; 63(4): 423-438, 2024 Apr.
Artigo
Inglês
| MEDLINE | ID: mdl-38609704
8.
Exposure-safety and exposure-efficacy analyses for tisotumab vedotin for patients with locally advanced or metastatic solid tumors.
CPT Pharmacometrics Syst Pharmacol
; 12(9): 1262-1273, 2023 09.
Artigo
Inglês
| MEDLINE | ID: mdl-37496366
9.
Population pharmacokinetic analysis for tisotumab vedotin in patients with locally advanced and/or metastatic solid tumors.
CPT Pharmacometrics Syst Pharmacol
; 11(10): 1358-1370, 2022 10.
Artigo
Inglês
| MEDLINE | ID: mdl-35932175
10.
Effect of raltegravir on estradiol and norgestimate plasma pharmacokinetics following oral contraceptive administration in healthy women.
Br J Clin Pharmacol
; 71(4): 616-20, 2011 Apr.
Artigo
Inglês
| MEDLINE | ID: mdl-21395656
11.
Pharmacokinetics of the Monoclonal Antibody MHAA4549A Administered in Combination With Oseltamivir in Patients Hospitalized With Severe Influenza A Infection.
J Clin Pharmacol
; 60(11): 1509-1518, 2020 11.
Artigo
Inglês
| MEDLINE | ID: mdl-32621543
12.
Effects of omeprazole on plasma levels of raltegravir.
Clin Infect Dis
; 48(4): 489-92, 2009 Feb 15.
Artigo
Inglês
| MEDLINE | ID: mdl-19143531
13.
Effect of tipranavir-ritonavir on pharmacokinetics of raltegravir.
Antimicrob Agents Chemother
; 53(7): 2752-5, 2009 Jul.
Artigo
Inglês
| MEDLINE | ID: mdl-19398643
14.
Lack of a clinically important effect of moderate hepatic insufficiency and severe renal insufficiency on raltegravir pharmacokinetics.
Antimicrob Agents Chemother
; 53(5): 1747-52, 2009 May.
Artigo
Inglês
| MEDLINE | ID: mdl-19223645
15.
Effect of rifampin, a potent inducer of drug-metabolizing enzymes, on the pharmacokinetics of raltegravir.
Antimicrob Agents Chemother
; 53(7): 2852-6, 2009 Jul.
Artigo
Inglês
| MEDLINE | ID: mdl-19433563
16.
Assessment of Drug Interaction Potential Between the Hepatitis C Virus Direct-Acting Antiviral Agents Elbasvir/Grazoprevir and the Nucleotide Analog Reverse-Transcriptase Inhibitor Tenofovir Disoproxil Fumarate.
Clin Pharmacol Drug Dev
; 8(7): 962-970, 2019 10.
Artigo
Inglês
| MEDLINE | ID: mdl-31173674
17.
Lack of a pharmacokinetic effect of raltegravir on midazolam: in vitro/in vivo correlation.
J Clin Pharmacol
; 48(2): 209-14, 2008 Feb.
Artigo
Inglês
| MEDLINE | ID: mdl-18077730
18.
Pharmacokinetics of MHAA4549A, an Anti-Influenza A Monoclonal Antibody, in Healthy Subjects Challenged with Influenza A Virus in a Phase IIa Randomized Trial.
Clin Pharmacokinet
; 57(3): 367-377, 2018 03.
Artigo
Inglês
| MEDLINE | ID: mdl-28639229
19.
Phase II Study of the Dual EGFR/HER3 Inhibitor Duligotuzumab (MEHD7945A) versus Cetuximab in Combination with FOLFIRI in Second-Line RAS Wild-Type Metastatic Colorectal Cancer.
Clin Cancer Res
; 24(10): 2276-2284, 2018 05 15.
Artigo
Inglês
| MEDLINE | ID: mdl-29506988
20.
Receptor-ligand binding: 'catch' bonds finally caught.
Curr Biol
; 13(15): R611-3, 2003 Aug 05.
Artigo
Inglês
| MEDLINE | ID: mdl-12906816