Detalhe da pesquisa
1.
Targeting Troponin C with Small Molecules Containing Diphenyl Moieties: Calcium Sensitivity Effects on Striated Muscles and Structure-Activity Relationship.
J Chem Inf Model
; 63(11): 3462-3473, 2023 06 12.
Artigo
Inglês
| MEDLINE | ID: mdl-37204863
2.
Actives-Based Receptor Selection Strongly Increases the Success Rate in Structure-Based Drug Design and Leads to Identification of 22 Potent Cancer Inhibitors.
J Chem Inf Model
; 62(22): 5675-5687, 2022 11 28.
Artigo
Inglês
| MEDLINE | ID: mdl-36321808
3.
Computational Exploration and Characterization of Potential Calcium Sensitizing Mutations in Cardiac Troponin C.
J Chem Inf Model
; 62(23): 6201-6208, 2022 Dec 12.
Artigo
Inglês
| MEDLINE | ID: mdl-36383927
4.
Adaptative Steered Molecular Dynamics Study of Mutagenesis Effects on Calcium Affinity in the Regulatory Domain of Cardiac Troponin C.
J Chem Inf Model
; 61(6): 3052-3057, 2021 06 28.
Artigo
Inglês
| MEDLINE | ID: mdl-34080877
5.
Targeting Troponin C with Small Molecules Containing Diphenyl Moieties: Calcium Sensitivity Effects on Striated Muscle and Structure Activity Relationship.
bioRxiv
; 2023 Feb 06.
Artigo
Inglês
| MEDLINE | ID: mdl-36798160
6.
Applications of machine learning in computer-aided drug discovery.
QRB Discov
; 3: e14, 2022.
Artigo
Inglês
| MEDLINE | ID: mdl-37529294
7.
The effect of Mg2+ on Ca2+ binding to cardiac troponin C in hypertrophic cardiomyopathy associated TNNC1 variants.
FEBS J
; 289(23): 7446-7465, 2022 12.
Artigo
Inglês
| MEDLINE | ID: mdl-35838319