Detalhe da pesquisa
1.
Rational design of prodrug-type apoB-targeted siRNA for nuclease resistance improvement without compromising gene silencing potency.
Bioorg Med Chem
; 104: 117693, 2024 Apr 15.
Artigo
Inglês
| MEDLINE | ID: mdl-38552598
2.
2023 Update on European Atherosclerosis Society Consensus Statement on Homozygous Familial Hypercholesterolaemia: new treatments and clinical guidance.
Eur Heart J
; 44(25): 2277-2291, 2023 Jul 01.
Artigo
Inglês
| MEDLINE | ID: mdl-37130090
3.
Worldwide experience of homozygous familial hypercholesterolaemia: retrospective cohort study.
Lancet
; 399(10326): 719-728, 2022 02 19.
Artigo
Inglês
| MEDLINE | ID: mdl-35101175
4.
Prodrug-Type Phosphotriester Oligonucleotides with Linear Disulfide Promoieties Responsive to Reducing Environment.
Chembiochem
; 24(24): e202300526, 2023 12 14.
Artigo
Inglês
| MEDLINE | ID: mdl-37840006
5.
Deficiency of Cardiac Natriuretic Peptide Signaling Promotes Peripartum Cardiomyopathy-Like Remodeling in the Mouse Heart.
Circulation
; 141(7): 571-588, 2020 02 18.
Artigo
Inglês
| MEDLINE | ID: mdl-31665900
6.
Comprehensive analysis of mechanism underlying hypouricemic effect of glucosyl hesperidin.
Biochem Biophys Res Commun
; 521(4): 861-867, 2020 01 22.
Artigo
Inglês
| MEDLINE | ID: mdl-31711647
7.
The benign c.344G > A: p.(Arg115His) variant in the LDLR gene interpreted from a pedigree-based genetic analysis of familial hypercholesterolemia.
Lipids Health Dis
; 19(1): 62, 2020 Apr 06.
Artigo
Inglês
| MEDLINE | ID: mdl-32252761
8.
Spontaneous rupture of Achilles tendon xanthomas in a case of familial hypercholesterolaemia.
Lancet
; 401(10371): 140, 2023 01 14.
Artigo
Inglês
| MEDLINE | ID: mdl-36641200
9.
Pharmaceutical Research for Inherited Metabolic Disorders of the Liver Using Human Induced Pluripotent Stem Cell and Genome Editing Technologies.
Biol Pharm Bull
; 42(3): 312-318, 2019.
Artigo
Inglês
| MEDLINE | ID: mdl-30828061
10.
Crude α-Mangostin Suppresses the Development of Atherosclerotic Lesions in Apoe-Deficient Mice by a Possible M2 Macrophage-Mediated Mechanism.
Int J Mol Sci
; 20(7)2019 Apr 07.
Artigo
Inglês
| MEDLINE | ID: mdl-30959963
11.
Effective gene silencing activity of prodrug-type 2'-O-methyldithiomethyl siRNA compared with non-prodrug-type 2'-O-methyl siRNA.
Bioorg Med Chem Lett
; 28(12): 2171-2174, 2018 07 01.
Artigo
Inglês
| MEDLINE | ID: mdl-29764744
12.
Current concept and residual issues of lipoprotein(a) determination for a cardiovascular risk factor.
Eur J Clin Invest
; 52(1): e13700, 2022 Jan.
Artigo
Inglês
| MEDLINE | ID: mdl-34747007
13.
Association Between Cholesterol Efflux Capacity and Atherosclerotic Cardiovascular Disease in Patients With Familial Hypercholesterolemia.
Arterioscler Thromb Vasc Biol
; 36(1): 181-8, 2016 Jan.
Artigo
Inglês
| MEDLINE | ID: mdl-26543100
14.
Achilles Tendon Ultrasonography for Diagnosis of Familial Hypercholesterolemia Among Japanese Subjects.
Circ J
; 81(12): 1879-1885, 2017 Nov 24.
Artigo
Inglês
| MEDLINE | ID: mdl-28652530
15.
LDL apheresis in Japan.
Transfus Apher Sci
; 56(5): 677-681, 2017 Oct.
Artigo
Inglês
| MEDLINE | ID: mdl-28964708
16.
Efficacy and safety of alirocumab in patients with hypercholesterolemia not adequately controlled with non-statin lipid-lowering therapy or the lowest strength of statin: ODYSSEY NIPPON study design and rationale.
Lipids Health Dis
; 16(1): 121, 2017 Jun 17.
Artigo
Inglês
| MEDLINE | ID: mdl-28623954
17.
A Novel Strategy for Etiologic Factor Removal: Drug-Navigated Clearance System (DNCS).
Chem Pharm Bull (Tokyo)
; 65(7): 649-652, 2017.
Artigo
Inglês
| MEDLINE | ID: mdl-28674338
18.
Pathological and molecular analyses of atherosclerotic lesions in ApoE-knockout mice.
Med Mol Morphol
; 50(3): 130-144, 2017 Sep.
Artigo
Inglês
| MEDLINE | ID: mdl-28247010
19.
Development of hypertriglyceridemia due to GPIHBP1 autoantibodies prior to clinical diagnosis of systemic lupus erythematosus in a 14-year-old girl.
Allergol Int
; 71(4): 555-557, 2022 10.
Artigo
Inglês
| MEDLINE | ID: mdl-35662538
20.
Evaluations of Intravenous Administration of CD34+ Human Umbilical Cord Blood Cells in a Mouse Model of Neonatal Hypoxic-Ischemic Encephalopathy.
Dev Neurosci
; 38(5): 331-341, 2016.
Artigo
Inglês
| MEDLINE | ID: mdl-28103599