Detalhe da pesquisa
1.
14-3-3 interaction with phosphodiesterase 8A sustains PKA signaling and downregulates the MAPK pathway.
J Biol Chem
; 300(3): 105725, 2024 Mar.
Artigo
Inglês
| MEDLINE | ID: mdl-38325743
2.
Cryo-Electron Microscopy Structure of the Mycobacterium tuberculosis Cytochrome bcc:aa3 Supercomplex and a Novel Inhibitor Targeting Subunit Cytochrome cI.
Antimicrob Agents Chemother
; 67(6): e0153122, 2023 06 15.
Artigo
Inglês
| MEDLINE | ID: mdl-37158740
3.
Structure activity relationship of pyrazinoic acid analogs as potential antimycobacterial agents.
Bioorg Med Chem
; 74: 117046, 2022 11 15.
Artigo
Inglês
| MEDLINE | ID: mdl-36228522
4.
Targeting the menaquinol binding loop of mycobacterial cytochrome bd oxidase.
Mol Divers
; 25(1): 517-524, 2021 Feb.
Artigo
Inglês
| MEDLINE | ID: mdl-31939065
5.
Discovery of a Novel Mycobacterial F-ATP Synthase Inhibitor and its Potency in Combination with Diarylquinolines.
Angew Chem Int Ed Engl
; 59(32): 13295-13304, 2020 08 03.
Artigo
Inglês
| MEDLINE | ID: mdl-32337801
6.
Combination of pharmacophore hypothesis and molecular docking to identify novel inhibitors of HCV NS5B polymerase.
Mol Divers
; 19(3): 529-39, 2015 Aug.
Artigo
Inglês
| MEDLINE | ID: mdl-25862642
7.
NMR solution structure of C2 domain of MFG-E8 and insights into its molecular recognition with phosphatidylserine.
Biochim Biophys Acta
; 1828(3): 1083-93, 2013 Mar.
Artigo
Inglês
| MEDLINE | ID: mdl-23262193
8.
Crystal structure of Plasmodium vivax FK506-binding protein 25 reveals conformational changes responsible for its noncanonical activity.
Proteins
; 82(7): 1235-44, 2014 Jul.
Artigo
Inglês
| MEDLINE | ID: mdl-24302348
9.
The flavonoid myricetin reduces nocturnal melatonin levels in the blood through the inhibition of serotonin N-acetyltransferase.
Biochem Biophys Res Commun
; 440(2): 312-6, 2013 Oct 18.
Artigo
Inglês
| MEDLINE | ID: mdl-24076393
10.
Novel targets and inhibitors of the Mycobacterium tuberculosis cytochrome bd oxidase to foster anti-tuberculosis drug discovery.
Expert Opin Drug Discov
; 18(8): 917-927, 2023.
Artigo
Inglês
| MEDLINE | ID: mdl-37332221
11.
Coomassie brilliant blue G-250 acts as a potential chemical chaperone to stabilize therapeutic insulin.
Chem Commun (Camb)
; 59(52): 8095-8098, 2023 Jun 27.
Artigo
Inglês
| MEDLINE | ID: mdl-37293871
12.
GaMF1.39's antibiotic efficacy and its enhanced antitubercular activity in combination with clofazimine, Telacebec, ND-011992, or TBAJ-876.
Microbiol Spectr
; 11(6): e0228223, 2023 Dec 12.
Artigo
Inglês
| MEDLINE | ID: mdl-37982630
13.
Solution structure of FK506-binding protein 12 from Aedes aegypti.
Proteins
; 80(10): 2476-81, 2012 Oct.
Artigo
Inglês
| MEDLINE | ID: mdl-22806993
14.
Mutational Analysis of Mycobacterial F-ATP Synthase Subunit δ Leads to a Potent δ Enzyme Inhibitor.
ACS Chem Biol
; 17(3): 529-535, 2022 03 18.
Artigo
Inglês
| MEDLINE | ID: mdl-35148057
15.
Atomic solution structure of Mycobacterium abscessus F-ATP synthase subunit ε and identification of Ep1MabF1 as a targeted inhibitor.
FEBS J
; 289(20): 6308-6323, 2022 10.
Artigo
Inglês
| MEDLINE | ID: mdl-35612822
16.
Structural and Mechanistic Insights into Mycobacterium abscessus Aspartate Decarboxylase PanD and a Pyrazinoic Acid-Derived Inhibitor.
ACS Infect Dis
; 8(7): 1324-1335, 2022 07 08.
Artigo
Inglês
| MEDLINE | ID: mdl-35731701
17.
Targeting C-terminal Helical bundle of NCOVID19 Envelope (E) protein.
Int J Biol Macromol
; 175: 131-139, 2021 Apr 01.
Artigo
Inglês
| MEDLINE | ID: mdl-33548321
18.
Deciphering the Role of Ion Channels in Early Defense Signaling against Herbivorous Insects.
Cells
; 10(9)2021 08 27.
Artigo
Inglês
| MEDLINE | ID: mdl-34571868
19.
Targeting Mycobacterial F-ATP Synthase C-Terminal α Subunit Interaction Motif on Rotary Subunit γ.
Antibiotics (Basel)
; 10(12)2021 Nov 26.
Artigo
Inglês
| MEDLINE | ID: mdl-34943667
20.
Antiviral activity against Middle East Respiratory Syndrome coronavirus by Montelukast, an anti-asthma drug.
Antiviral Res
; 185: 104996, 2021 01.
Artigo
Inglês
| MEDLINE | ID: mdl-33309540