Detalhe da pesquisa
1.
MM-131, a bispecific anti-Met/EpCAM mAb, inhibits HGF-dependent and HGF-independent Met signaling through concurrent binding to EpCAM.
Proc Natl Acad Sci U S A
; 116(15): 7533-7542, 2019 04 09.
Artigo
Inglês
| MEDLINE | ID: mdl-30898885
2.
Methamphetamine use and heart failure: Prevalence, risk factors, and predictors.
Am J Emerg Med
; 36(8): 1423-1428, 2018 08.
Artigo
Inglês
| MEDLINE | ID: mdl-29307766
3.
Pathways for Neoarchean pyrite formation constrained by mass-independent sulfur isotopes.
Proc Natl Acad Sci U S A
; 110(44): 17638-43, 2013 Oct 29.
Artigo
Inglês
| MEDLINE | ID: mdl-23407162
4.
Understanding the role of cross-arm binding efficiency in the activity of monoclonal and multispecific therapeutic antibodies.
Methods
; 65(1): 95-104, 2014 Jan 01.
Artigo
Inglês
| MEDLINE | ID: mdl-23872324
5.
Evidence of magnetic isotope effects during thermochemical sulfate reduction.
Proc Natl Acad Sci U S A
; 108(43): 17635-8, 2011 Oct 25.
Artigo
Inglês
| MEDLINE | ID: mdl-21997216
6.
Systems biology driving drug development: from design to the clinical testing of the anti-ErbB3 antibody seribantumab (MM-121).
NPJ Syst Biol Appl
; 3: 16034, 2017.
Artigo
Inglês
| MEDLINE | ID: mdl-28725482
7.
Motility signaled from the EGF receptor and related systems.
Methods Mol Biol
; 327: 159-77, 2006.
Artigo
Inglês
| MEDLINE | ID: mdl-16780220
8.
MM-141, an IGF-IR- and ErbB3-directed bispecific antibody, overcomes network adaptations that limit activity of IGF-IR inhibitors.
Mol Cancer Ther
; 13(2): 410-25, 2014 Feb.
Artigo
Inglês
| MEDLINE | ID: mdl-24282274
9.
Lessons learned from quantitative dynamical modeling in systems biology.
PLoS One
; 8(9): e74335, 2013.
Artigo
Inglês
| MEDLINE | ID: mdl-24098642
10.
Optimizing properties of antireceptor antibodies using kinetic computational models and experiments.
Methods Enzymol
; 502: 67-87, 2012.
Artigo
Inglês
| MEDLINE | ID: mdl-22208982
11.
Impact of intrinsic affinity on functional binding and biological activity of EGFR antibodies.
Mol Cancer Ther
; 11(7): 1467-76, 2012 Jul.
Artigo
Inglês
| MEDLINE | ID: mdl-22564724
12.
Antitumor activity of a novel bispecific antibody that targets the ErbB2/ErbB3 oncogenic unit and inhibits heregulin-induced activation of ErbB3.
Mol Cancer Ther
; 11(3): 582-93, 2012 Mar.
Artigo
Inglês
| MEDLINE | ID: mdl-22248472
13.
Systems biologists seek fuller integration of systems biology approaches in new cancer research programs.
Cancer Res
; 70(1): 12-3, 2010 Jan 01.
Artigo
Inglês
| MEDLINE | ID: mdl-20028868
14.
Therapeutically targeting ErbB3: a key node in ligand-induced activation of the ErbB receptor-PI3K axis.
Sci Signal
; 2(77): ra31, 2009 Jun 30.
Artigo
Inglês
| MEDLINE | ID: mdl-19567914
15.
Quantitative analysis of Akt phosphorylation and activity in response to EGF and insulin treatment.
Biochem Biophys Res Commun
; 354(1): 14-20, 2007 Mar 02.
Artigo
Inglês
| MEDLINE | ID: mdl-17214972
16.
Directional persistence of EGF-induced cell migration is associated with stabilization of lamellipodial protrusions.
Biophys J
; 88(2): 1479-88, 2005 Feb.
Artigo
Inglês
| MEDLINE | ID: mdl-15713602